Immune cells injected directly into brain show promise for kids with tough tumors

This early-stage study tested a new treatment for children and young adults with brain tumors that came back or didn't respond to standard therapy. Doctors took the patients' own immune cells, modified them to recognize a protein called EGFR on tumor cells, and injected them directly into the brain. The goal was to see if this approach is safe and possible, and to measure how the cells spread and work against the tumors.