Can a Child's tumor DNA guide better cancer treatment?
NCT ID NCT02162732
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether analyzing the DNA and RNA of a child's tumor could help doctors choose personalized treatments. It included 186 children with relapsed or hard-to-treat cancers like neuroblastoma and brain tumors. The goal was to see if this approach was feasible and safe, not to cure the cancer directly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this approach could help doctors select more effective treatments for children with hard-to-treat cancers based on their tumor's unique genetic makeup.
What could go wrong
This was an early feasibility study, not a treatment trial. It tested whether the technology works, not whether it improves outcomes. Results may not lead to better survival.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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American University of Beirut Medical Center
Beirut, Lebanon
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Arkansas Children's Hospital
Little Rock, Arkansas, 72202, United States
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Arnold Palmer Hospital for Children
Orlando, Florida, 32806, United States
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Cardinal Glennon Children's Medical Center
St Louis, Missouri, 63104, United States
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Children's Hospital and Clinics on Minnesota
Minneapolis, Minnesota, 55404, United States
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Children's Mercy Hospitals and Clinics
Kansas City, Missouri, 64108, United States
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Connecticut Children's Hospital
Hartford, Connecticut, 06106, United States
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Dell Children's Blood and Cancer Center
Austin, Texas, 78723, United States
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Helen DeVos Children's Hospital
Grand Rapids, Michigan, 49503, United States
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Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, 96813, United States
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Levine Children's Hospital
Charlotte, North Carolina, 28204, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Monroe Carrell Jr. Children's Hospital at Vanderbilt
Nashville, Tennessee, 37232, United States
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Penn State Milton S. Hershey Medical Center and Children's Hospital
Hershey, Pennsylvania, 17033, United States
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Primary Children's Hospital
Salt Lake City, Utah, 84113, United States
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Rady Children's Hospital
San Diego, California, 92123, United States
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Randall Children's Hospital
Portland, Oregon, United States
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Texas Children's Cancer and Hematology Centers
Houston, Texas, 77030, United States
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The Children's Hospital at Montefiore
The Bronx, New York, 10467, United States