Can a Child's tumor DNA guide better cancer treatment?
NCT ID NCT02162732
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether analyzing the DNA and RNA of a child's tumor could help doctors choose personalized treatments. It included 186 children with relapsed or hard-to-treat cancers like neuroblastoma and brain tumors. The goal was to see if this approach was feasible and safe, not to cure the cancer directly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this approach could help doctors select more effective treatments for children with hard-to-treat cancers based on their tumor's unique genetic makeup.
- What could go wrong
- This was an early feasibility study, not a treatment trial. It tested whether the technology works, not whether it improves outcomes. Results may not lead to better survival.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHOROID PLEXUS NEOPLASMS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
American University of Beirut Medical Center
Beirut, Lebanon
-
Arkansas Children's Hospital
Little Rock, Arkansas, 72202, United States
-
Arnold Palmer Hospital for Children
Orlando, Florida, 32806, United States
-
Cardinal Glennon Children's Medical Center
St Louis, Missouri, 63104, United States
-
Children's Hospital and Clinics on Minnesota
Minneapolis, Minnesota, 55404, United States
-
Children's Mercy Hospitals and Clinics
Kansas City, Missouri, 64108, United States
-
Connecticut Children's Hospital
Hartford, Connecticut, 06106, United States
-
Dell Children's Blood and Cancer Center
Austin, Texas, 78723, United States
-
Helen DeVos Children's Hospital
Grand Rapids, Michigan, 49503, United States
-
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, 96813, United States
-
Levine Children's Hospital
Charlotte, North Carolina, 28204, United States
-
Medical University of South Carolina
Charleston, South Carolina, 29425, United States
-
Monroe Carrell Jr. Children's Hospital at Vanderbilt
Nashville, Tennessee, 37232, United States
-
Penn State Milton S. Hershey Medical Center and Children's Hospital
Hershey, Pennsylvania, 17033, United States
-
Primary Children's Hospital
Salt Lake City, Utah, 84113, United States
-
Rady Children's Hospital
San Diego, California, 92123, United States
-
Randall Children's Hospital
Portland, Oregon, United States
-
Texas Children's Cancer and Hematology Centers
Houston, Texas, 77030, United States
-
The Children's Hospital at Montefiore
The Bronx, New York, 10467, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can trained immune cells outsmart brain tumors?
- Can the Body's own immune cells beat a recurrent brain tumor?
- A simple blood test may reveal hidden infertility risk in young cancer survivors
- Can a Tumor's genetic blueprint guide better treatment for kids with brain cancer?
- Can adding lenvatinib to standard care outsmart a tough brain cancer?
- Can we predict who needs extra therapy after kidney cancer surgery?