ASTROCYTOMA

This early-stage study is testing a new combination treatment for adults with aggressive brain cancer that has returned after prior therapy. After surgeons remove as much tumor as possible, a modified virus is injected into the area to target remaining cancer cells. The main goal…

This study aims to find a safe and effective schedule for delivering a second round of radiation to treat glioblastoma brain tumors that have returned after initial treatment. It will enroll 28 adults whose cancer has come back, testing radiation given four times a week for one, …

This study is testing the safety of an experimental virus therapy called G207 for children and young adults with recurrent or hard-to-treat brain tumors in the cerebellum. The virus is designed to infect and kill cancer cells while sparing healthy ones. Researchers will also test…

This study is testing whether combining an oral vitamin A-based drug (ATRA) with an immunotherapy (retifanlimab) can help control a specific type of recurrent brain tumor called IDH-mutant glioma. It aims to see if this combination is safe and can stimulate the patient's own immu…

This study is testing whether the drug tuvusertib can help control recurrent brain tumors called astrocytomas that have specific genetic mutations. It will involve 56 adults whose cancer has returned after initial treatment. The main goal is to see if the drug can keep the cancer…

This study is testing if the blood-thinning medication apixaban can safely prevent dangerous blood clots in people newly diagnosed with aggressive brain tumors (grade 4 glioma). It will involve about 40 adult patients who are starting radiation and chemotherapy. The main goal is …

This study is testing a new psychological support program called FearLess, designed to help people with brain tumors and their caregivers manage the fear of the cancer coming back. Researchers want to see if the program is practical, acceptable, and a good fit for participants. T…