Nanoparticles boost radiation against tough brain tumors
NCT ID NCT04899908
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding AGuIX gadolinium-based nanoparticles to standard brain radiation can better control brain metastases that are at high risk of coming back. About 134 adults with certain cancers (like melanoma, lung, breast, or colorectal) that have spread to the brain will receive either radiation alone or radiation plus the nanoparticles. The goal is to see if the nanoparticles help prevent the tumors from growing back.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02115, United States
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