Cure My Disease

Don't miss your cure!

 Log in / Sign up

Nanoparticles boost radiation against tough brain tumors

NCT ID NCT04899908

Recruiting now Disease control Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding AGuIX gadolinium-based nanoparticles to standard brain radiation can better control brain metastases that are at high risk of coming back. About 134 adults with certain cancers (like melanoma, lung, breast, or colorectal) that have spread to the brain will receive either radiation alone or radiation plus the nanoparticles. The goal is to see if the nanoparticles help prevent the tumors from growing back.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

aspartylglucosaminuria brain cancer brain neoplasm breast cancer breast neoplasm colorectal cancer colorectal neoplasm digestive system cancer digestive system neoplasm HER2 positive breast carcinoma lung cancer lung neoplasm melanoma metastatic malignant neoplasm in the brain Silver-Russell syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGUIX BRAIN CANCER BRAIN METASTASES BRAIN TUMOR BREAST CANCER COLORECTAL CANCER CYSTIC GASTROINTESTINAL CANCER HER2-POSITIVE BREAST CANCER LUNG CANCER MELANOMA NANOPARTICLE SRS SRT STEREOTACTIC RADIATION WHOLE BRAIN RADIATION

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact