Brain cancer radiotherapy gets a precision boost from advanced MRI

NCT ID NCT07512154

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special MRI scan, called amide proton transfer (APT) imaging, can help doctors target the most aggressive parts of brain tumors during radiotherapy. Twenty adults with glioblastoma or grade 4 astrocytoma will receive either standard radiotherapy or a new APT-guided approach. The goal is to see if the new method reduces tumor activity more effectively.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Radiotherapy (APT-guided radiation)

What this could lead to

If successful, this could make radiotherapy for brain cancer more precise, potentially improving tumor control and reducing side effects.

What could go wrong

This is a small early-phase study with only 20 participants, so results may not apply widely. The new MRI technique may not improve outcomes over standard treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain cancer glioblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins University

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••