New light therapy aims to ease swallowing for esophageal cancer patients
NCT ID NCT03133650
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase trial tests a treatment called vascular-targeted photodynamic therapy (VTP) for people with advanced esophageal or stomach cancer who have moderate to severe trouble swallowing. The treatment uses a light-sensitive drug (WST-11) and a laser delivered through a thin tube into the esophagus to target the tumor. The main goal is to find the highest safe laser dose in 12 participants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
WST-11 (a light-activated drug) combined with laser light delivered via endoscope
What this could lead to
If it works, this could point toward a new way to relieve trouble swallowing in people with advanced esophageal cancer.
What could go wrong
This is a very early, small phase I trial with only 12 participants, so it is not yet proven to work. The main goal is to find a safe light dose, not to measure effectiveness.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Memorial Sloan - Kettering Cancer Center
New York, New York, 10021, United States
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Weill Cornell Medical Center (Data Analysis Only)
New York, New York, 10021, United States
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Weizmann Institute of Science
Rehovot, Israel