Could a single dose of methadone during surgery cut Post-Op pain?
NCT ID NCT05417100
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving methadone during spinal surgery helps control pain for the first 72 hours after surgery better than standard pain medicines. Seventeen adults having cancer-related spinal surgery took part. Researchers measured pain scores and how much extra pain medication was needed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- methadone
- What this could lead to
- If it works, this could point toward a better way to manage pain after spinal surgery, reducing the need for other opioids.
- What could go wrong
- This is a very small trial (17 people) and results may not apply to everyone. Methadone itself can cause side effects like breathing problems or nausea.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SPINAL SURGERY are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Ice cubes and lozenges: a new way to ease Post-Surgery discomfort?
- New device aims to cut opioid use after back surgery
- Spine surgery pain breakthrough? drug cocktail aims to stop chronic ache
- Back surgery breathing study seeks safer anesthesia settings
- Spine surgery showdown: robot vs. Surgeon's hand
- New drug cocktail aims to cut Post-Surgery pain in half