Could a single dose of methadone during surgery cut Post-Op pain?
NCT ID NCT05417100
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether giving methadone during spinal surgery helps control pain for the first 72 hours after surgery better than standard pain medicines. Seventeen adults having cancer-related spinal surgery took part. Researchers measured pain scores and how much extra pain medication was needed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
methadone
What this could lead to
If it works, this could point toward a better way to manage pain after spinal surgery, reducing the need for other opioids.
What could go wrong
This is a very small trial (17 people) and results may not apply to everyone. Methadone itself can cause side effects like breathing problems or nausea.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, 10065, United States