Can a children's chemo recipe help adults with leukemia? early trial adds venetoclax to the mix.
NCT ID NCT05386576
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tests whether adding venetoclax to a chemotherapy regimen originally designed for children is safe and effective for adults under 60 with newly diagnosed acute lymphoblastic leukemia (ALL). The study involves 12 participants and focuses on finding the right dose and checking for side effects. It is not yet known if this combination will improve outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Venetoclax (a targeted drug) combined with standard chemotherapy drugs used in children
- What this could lead to
- If it works, this could point toward a more effective and safer treatment for adults with acute lymphoblastic leukemia.
- What could go wrong
- This is a very early, small trial (12 people) focused on safety, not proof of effectiveness. The combination may cause serious side effects or not work better than existing treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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