Can a children's chemo recipe help adults with leukemia? early trial adds venetoclax to the mix.

NCT ID NCT05386576

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests whether adding venetoclax to a chemotherapy regimen originally designed for children is safe and effective for adults under 60 with newly diagnosed acute lymphoblastic leukemia (ALL). The study involves 12 participants and focuses on finding the right dose and checking for side effects. It is not yet known if this combination will improve outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Venetoclax (a targeted drug) combined with standard chemotherapy drugs used in children

What this could lead to

If it works, this could point toward a more effective and safer treatment for adults with acute lymphoblastic leukemia.

What could go wrong

This is a very early, small trial (12 people) focused on safety, not proof of effectiveness. The combination may cause serious side effects or not work better than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia lymphoblastic lymphoma Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States