Lung spot watch: new study tracks hazy lesions to predict cancer risk

NCT ID NCT03802981

Ongoing Knowledge-focused Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 338 people who have two or more ground glass opacities (GGOs) in their lungs—small, hazy spots seen on CT scans. Instead of treating them right away, doctors will monitor them over time to learn more about how these spots behave and whether they lead to lung cancer. The goal is to gather information that could help guide future care for people with similar findings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors better understand which GGOs are dangerous and which are safe to watch, potentially reducing unnecessary treatments.
What could go wrong: This is an observational registry, not a treatment trial. It may not provide clear answers about how to manage GGOs, and results may take years to emerge.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE GROUND GLASS OPACITIES (GGOS)

Contacts and locations

Locations

Allegheny Health Network

Pittsburgh, Pennsylvania, 15212, United States
Baylor University Medical Center

Houston, Texas, 77030, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
Centre Hospitalier de l'Université de Montreal

Montreal, Quebec, H2L 4M1, Canada
Duke University Medical Center

Durham, North Carolina, 27701, United States
Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States
George Washington University School of Medicine

St Louis, Missouri, 63110, United States
Hartford Healthcare

Hartford, Connecticut, 06102, United States
Lehigh Valley Health Network

Allentown, Pennsylvania, 18103, United States
MD Anderson Cancer Center

Houston, Texas, 77030-4009, United States
Massachusetts General Hospital Cancer Center

Boston, Massachusetts, 02114, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
McMaster University (Data Collection Only)

Hamilton, Ontario, L8N 3Z5, Canada
Memorial Sloan Kettering Basking Ridge

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Commack

Commack, New York, 11725, United States
Memorial Sloan Kettering Monmouth

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester

Harrison, New York, 10604, United States
New York Presbyterian Hospital

New York, New York, 10065, United States
Roswell Park Cancer Institute (Data Collection Only)

Buffalo, New York, 14263-0001, United States
Rush University Medical Center (Data collection only)

Chicago, Illinois, 606012, United States
Stanford University Medical Center (Data collection only)

Stanford, California, 94305-5408, United States
Temple University

Philadelphia, Pennsylvania, 19140, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
University Health Network

Toronto, Ontario, M5G 2C4, Canada
University of California San Diego

San Diego, California, 92103, United States
University of Michigan

Ann Arbor, Michigan, 48109, United States
University of Pennsylvania (Data Collection Only)

Philadelphia, Pennsylvania, 19104, United States
University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15213, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States

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