Tiny particles light up tumors in new imaging study

NCT ID NCT01266096

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a new radioactive dye attached to tiny silica particles to improve PET scans for people with melanoma or malignant brain tumors. Ten participants will receive a single injection of the tracer to see how it spreads in the body and how much radiation it gives off. The goal is to gather information for future imaging or treatment studies, not to treat the cancer itself.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

124I-cRGDY-PEG-dots (a radioactive dye attached to silica nanoparticles)

What this could lead to

If successful, this could lead to more accurate PET scans for detecting melanoma and brain tumors, helping doctors see cancer more clearly.

What could go wrong

This is a very early, small study with only 10 participants. It is not designed to treat cancer, and the findings may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain cancer melanoma metastatic melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States