Glow-in-the-Dark dye could help surgeons spot brain tumors
NCT ID NCT07438860
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests a fluorescent dye called SBK2-ICG in 12 adults with untreated malignant brain tumors. The dye is given before surgery to see if it can make tumor edges glow, helping surgeons remove as much tumor as possible while protecting healthy brain. The main goal is to check safety, with a secondary goal of seeing how well it works compared to an existing method.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SBK2-ICG (a fluorescent dye)
- What this could lead to
- If successful, this could help surgeons see tumor boundaries more clearly during brain surgery, potentially leading to more complete tumor removal while sparing healthy brain tissue.
- What could go wrong
- This is a very early Phase 1 safety study with only 12 participants. The dye may not work as hoped, or side effects could limit its use. It is not yet approved by the FDA.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Premier Health Neuroscience Institute
Dayton, Ohio, 45409, United States
Contact
Contact
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University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center
Cleveland, Ohio, 44106, United States
Contact
Contact
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Other studies related to the condition(s) this trial covers.
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