Thigh bone break fix: two surgeries face off in cancer patients

NCT ID NCT02164019

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two common surgeries for people whose thigh bone has been weakened by cancer spread. One surgery replaces the hip joint, the other uses a rod inside the bone. Researchers want to see which one leads to better function, quality of life, and pain control after surgery. 73 patients with cancer in the upper thigh bone are taking part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

long-stem cemented hemiarthroplasty (LSCH) or intramedullary nailing (IMN)

What this could lead to

If successful, this could help doctors choose the better surgery for patients with cancer-weakened thigh bones, improving their function and quality of life.

What could go wrong

This is a small, early-stage study with only 73 participants, so results may not apply to everyone. Both surgeries have risks like infection or implant failure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Fractures, Spontaneous

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Duke University

    Durham, North Carolina, 27708, United States

  • Memorial Sloan Kettering Cancer Center 1275 York Avenue

    New York, New York, 10065, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • SUNY Upstate Medical University

    Syracuse, New York, 13210, United States

  • Spectrum Health Medical Group

    Grand Rapids, Michigan, 49503, United States

  • University of Rochester Medical Center

    Rochester, New York, United States