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Study questions need for frequent heart checks in breast cancer therapy

NCT ID NCT03983382

Ongoing Knowledge-focused Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether people with HER2-positive breast cancer can safely have fewer heart check-ups while on a specific type of treatment (trastuzumab without anthracyclines). About 190 participants will be followed to see if less monitoring leads to serious heart problems. The goal is to make treatment less burdensome without compromising safety.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

  • Hartford Healthcare Cancer Institute @ Hartford Hospital (Data collection only)

    Hartford, Connecticut, 06102, United States

  • Memorial Sloan Kettering Bergen (Consent and follow-up only)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Cancer Center @ BaskingRidge (Consent and follow-up only)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Cancer Center @ Commack (Consent and Follow up)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth (Consent and Follow up)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Consent and Follow-up)

    Rockville Centre, New York, 11553, United States

  • Memorial Sloan Kettering Westchester (Consent and Follow-up)

    Harrison, New York, 10604, United States

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