Could brain MRIs and spinal taps predict breast cancer spread?
NCT ID NCT05130840
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study explores whether routine brain MRIs and spinal taps can detect early signs of breast cancer spreading to the brain in people with HER2-positive breast cancer. Researchers will enroll 9 participants to see if these tests are feasible and well-tolerated. The goal is to catch brain metastases before symptoms appear, enabling earlier treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this approach could help detect brain metastases earlier in HER2+ breast cancer patients, allowing for prompt treatment and possibly preventing disease progression.
What could go wrong
This is a very small feasibility study with only 9 participants, so results may not apply to all patients. The procedures (MRI and lumbar puncture) may be uncomfortable or not tolerated by everyone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States