Neurotic disorder

This study tests whether a short-term, intensive form of PTSD therapy can quickly reduce symptoms and improve thinking skills in military personnel. Participants receive either Cognitive Processing Therapy (CPT) or Eye Movement Desensitization and Reprocessing (EMDR) over a conde…

This phase 2 study tests whether the sleep medication suvorexant can reduce insomnia in 76 adults aged 21–65 who have both alcohol use disorder and posttraumatic stress disorder. Participants take either suvorexant or a placebo for 14 days while trying to stop drinking. The study…

This study tests a talk therapy called CETA for 300 mothers in a low-income area of Lima, Peru. The therapy aims to reduce depression, anxiety, and stress, and improve parenting and children's well-being. Another 300 mothers receive standard support. Researchers will follow famil…

This study compares a group program called Strength at Home (SAH) to standard court-mandated interventions for men who have used intimate partner violence (IPV) in Washington State. About 800 men will be randomly assigned to either SAH or treatment as usual, and researchers will …

This study tests a therapy toolkit called Signs of Safety, designed for Deaf individuals who use American Sign Language and struggle with alcohol use disorder and PTSD. The toolkit adapts an existing therapy (Seeking Safety) to be Deaf-accessible. Researchers compare it to treatm…

This study tests a short counseling program (about 4 sessions) designed to help pregnant and postpartum women in Cape Town, South Africa, keep taking their daily HIV-prevention pill (PrEP). Many women stop PrEP due to depression or trauma from violence. The program uses cognitive…

This study will enroll 1,000 adults with both opioid use disorder and a mental health condition. Participants will receive standard medication for opioid use disorder, with some also getting a team-based support program called MISSION. The goal is to see if MISSION helps people s…

This Phase 2 trial is testing whether HB-1, a tablet combining two blood pressure medications (telmisartan and verapamil), can safely reduce PTSD symptoms. About 200 adults aged 18-65 with PTSD will receive either HB-1 or a placebo daily for 12 weeks. The main goal is to see if H…

This study tests a stepped care program called PCT+2HOPE for women with opioid use disorder who have also experienced intimate partner violence and PTSD symptoms. The program adds group and individual therapy to standard medication treatment. Researchers will see if it helps wome…

This study tests whether MDMA-assisted therapy can help veterans with both PTSD and alcohol use disorder. Eighty veterans will receive either a full dose of MDMA or a low-dose placebo during three therapy sessions. Researchers will measure changes in PTSD symptoms and drinking ha…

This study tests a combined therapy for mothers with PTSD who are already receiving child welfare prevention services. The treatment blends skills to manage emotions and trauma with parent-child interaction coaching. Researchers will track changes in PTSD, depression, parenting b…

This study tests a program called Tunawiri (meaning 'thrive') that adds mental health screening, counseling, and support to regular HIV care for pregnant and postpartum women in Kenya. The goal is to improve depression, anxiety, and HIV treatment success. Nine hundred women will …

This study tests a gamified mobile health app designed to reduce suicide risk in adults with mental disorders after they leave the hospital. Researchers will enroll 640 participants in Shenzhen, China, and use game-like features to encourage treatment adherence and follow-up visi…

This study tests a 9-session program called MILAP for young married women (ages 15-24) in Nepal who have experienced intimate partner violence. The program involves the woman, her husband, and her mother-in-law, aiming to reduce depression, violence, and PTSD. 900 participants wi…

This study tests whether a drug called BXCL501, given as a film under the tongue, can reduce acute stress and prevent post-traumatic stress disorder (PTSD) in people who have been in a motor vehicle collision. One hundred adults who come to the emergency department within 72 hour…

This study tests a program called HARPP that combines proven treatments for PTSD and weight management into a single therapy for veterans. The goal is to see if this integrated approach leads to greater weight loss and PTSD symptom reduction compared to standard care. The study w…

This small study is testing whether MDMA-assisted therapy can help new mothers who have both post-traumatic stress disorder (PTSD) and opioid use disorder. Fifteen participants will receive MDMA in a controlled setting along with therapy sessions. The goal is to see if this appro…

This study tests whether a trauma-focused group therapy (CPT-CJ) given in prison can reduce drug use, PTSD symptoms, and re-arrest after release. 640 incarcerated adults from about 10 prisons will either receive the group therapy or a self-help workbook. Researchers will also mea…

This study tests whether giving e-cigarettes to smokers with mental illness—along with optional behavioral coaching—helps them switch from regular cigarettes and lower their exposure to harmful chemicals. The trial enrolls 250 daily smokers who have tried to quit before but aren'…

This study compares two treatments for veterans with PTSD who are at high risk for suicide. One group receives Dialectical Behavior Therapy (DBT) plus a special PTSD exposure protocol, while the other gets standard prolonged exposure therapy with suicide risk management. The goal…

This study tests whether a non-invasive brain stimulation technique called TMS can help people with mental illness quit smoking. Forty daily smokers with psychiatric conditions will receive either TMS or standard care. The goal is to see if TMS is practical and effective in real-…

This study looks at whether treating obstructive sleep apnea (OSA) early with a positive airway pressure (PAP) device can improve outcomes for veterans with both PTSD and substance use disorder. About 194 veterans in a residential treatment program will either receive PAP therapy…

This study tests whether reducing PTSD symptoms can prevent acute pain from turning into chronic pain. Researchers will give 345 adults either a nerve block injection (stellate ganglion block) or trauma-focused talk therapy (cognitive processing therapy). The goal is to see if th…

This study looks at two different sedative medicines given to children on breathing machines in the ICU. The goal is to see which one causes less confusion (delirium) and helps the brain recover better. About 372 children up to age 11 will take part. The results could change how …

This study tests a new iPhone app called Senseye DT that uses artificial intelligence to diagnose Post-Traumatic Stress Disorder (PTSD) in adults. Participants will use the app while it records video of their face, and the AI looks for signs of PTSD. The goal is to see if the app…

This study tests whether a non-invasive brain stimulation technique called TMS, given within two weeks of a traumatic event, can prevent chronic PTSD. Researchers will measure changes in brain activity linked to fear and threat. The goal is to see if early intervention can reduce…

This study tests a simple talking therapy for heart surgery patients while they are still in the ICU. The therapy uses a visitor book with photos and family messages to help patients process stressful memories. Researchers hope this can prevent posttraumatic stress disorder (PTSD…

This study tests a simple writing exercise for new mothers who had a stressful childbirth. In the days after giving birth, participants write about their experience for 15 minutes a day for three days. The goal is to see if this can prevent post-traumatic stress disorder (PTSD) a…

This study tests whether community health workers can help adults with chronic illnesses get up-to-date on COVID-19 and flu vaccines. Participants receive up to three counseling sessions in English or Spanish to address their vaccine concerns. The goal is to reduce health dispari…

This study is creating and testing short videos for teens (ages 12-17) and their parents after a traumatic injury that requires a hospital stay. The goal is to prevent posttraumatic stress disorder (PTSD) and substance use. The videos will be developed with input from families an…

This study tests whether an online, therapist-guided therapy called CIPE can prevent PTSD in people who recently experienced a traumatic event. About 360 adults receiving support from crisis teams will either get CIPE plus usual care or usual care alone. The goal is to see if ear…

This pilot study tests whether a breathing technique called cardiac coherence can prevent chronic PTSD in people who recently experienced a traumatic event. 44 participants with acute stress disorder will practice the breathing exercises for 3 months. The goal is to see if this s…

This study tests whether a short form of exposure therapy, given soon after a traumatic injury, can prevent posttraumatic stress disorder (PTSD). Researchers will enroll 300 injured adults admitted to Level I trauma centers. Half will receive the brief therapy plus standard care,…

This study tests a smartphone-based program called RISE Guide for women who have just been sexually assaulted. The goal is to see if it can reduce anxiety sensitivity and prevent posttraumatic stress disorder (PTSD) and cannabis use disorder (CUD). 68 women who seek emergency car…

This study tests a new way to treat post-traumatic stress disorder (PTSD) using personalized brain stimulation. Researchers use an EEG to find the right frequency for each person, then apply transcranial magnetic stimulation (TMS) to the frontal lobe. The trial includes 20 vetera…

This study tests whether a four-session mindfulness class (Primary Care Brief Mindfulness Training) can help veterans reduce symptoms of anxiety, depression, and PTSD compared to a problem-solving class. The classes are designed for primary care settings and focus on meditation, …

This trial tests whether starting PTSD treatment with one type of talk therapy and then switching to another based on early progress leads to better symptom relief. About 430 adults receiving care at federally qualified health centers will take part. The study compares different …

This study tests whether a drug called MDMA, given alongside therapy, can help veterans with PTSD feel better. About 52 veterans will receive a dose of MDMA during therapy sessions, either alone or in a group. The goal is to see if this approach is safe and reduces PTSD symptoms.

This study tests whether a brief form of talk therapy, called Prolonged Exposure for Primary Care (PE-PC), can reduce PTSD symptoms in first responders and frontline healthcare workers. Participants receive 4-6 weekly 30-minute sessions either by telehealth or in person, delivere…

This study tests whether a drug called psilocybin (the active ingredient in magic mushrooms) combined with therapy can help women with PTSD from sexual assault. About 70 women will receive the treatment in a controlled setting. The goal is to see if it reduces PTSD symptoms and i…

This study tests whether taking photos of things related to well-being and discussing them with a therapist can help people with stress-related illness. Participants take pictures with their phone before sessions, and the therapist uses the photos to guide conversations about wel…

This study tests whether adding a crisis response plan (CRP) to prolonged exposure (PE) therapy helps reduce suicidal thoughts and behaviors in people with PTSD. Researchers will compare PE plus CRP to PE with standard care in 100 adults. The goal is to find a better way to suppo…

This study tests whether sitting in front of a bright lightbox for 60 minutes each morning can improve sleep and overall well-being in veterans who have traumatic brain injury, post-traumatic stress disorder, and chronic pain together—known as the polytrauma clinical triad. The t…

This study tests whether a single dose of psilocybin (the active ingredient in magic mushrooms) combined with intensive therapy can help people with chronic posttraumatic stress disorder (PTSD). Fifteen adults with moderate to severe PTSD will receive the treatment over a week. T…

This study is testing whether a single dose of psilocybin (the active ingredient in magic mushrooms) combined with mindfulness-based therapy can help people with PTSD. Thirty adults with PTSD will receive psilocybin along with either standard support or extra mindfulness training…

This study tests whether answering a short daily survey about a specific traumatic memory can reduce the intensity and frequency of intrusive PTSD symptoms. Fifty adults with PTSD will either complete surveys about their trauma memory or about a neutral memory for 10 days. Resear…

This study aims to find helpful treatments for healthcare workers suffering from PTSD and distress due to work-related trauma. In the first phase, 120 participants will be randomly assigned to either a music-listening or a writing session over two weeks. Those who still have PTSD…

This study tests an internet-based cognitive behavioural therapy (ICBT) program designed specifically for Canadian public safety personnel (like police, firefighters, and paramedics) who have symptoms of depression, anxiety, or posttraumatic stress. Participants choose their leve…

This study tests a short, virtual therapy for pregnant women and new mothers with PTSD. About 90 participants will either receive the therapy or standard care. The goal is to see if the therapy is practical and well-liked, and to measure its effect on PTSD and depression symptoms…

This study tests a hybrid dialectical behavior therapy (DBT) program for veterans with PTSD who have already completed inpatient treatment. The goal is to reduce lingering symptoms and prevent relapse. About 24 veterans will take part, combining in-person skill groups with online…

This study compares two ways of delivering cognitive processing therapy (CPT) to pregnant women with posttraumatic stress disorder (PTSD). One group receives standard weekly therapy sessions for 12 weeks, while the other gets an intensive schedule of 10 sessions over just 5 days.…

This study tests a program called Parenting STAIR Modular (PSTAIR-M) for military-connected mothers who have experienced trauma and have young children aged 2-10. The program helps mothers manage PTSD and depression symptoms while improving their parenting skills. Researchers wil…

This pilot study is testing a 12-session virtual therapy that combines two proven treatments—one for PTSD and one for chronic pain—into a single program. Researchers want to see if this integrated approach is feasible and acceptable for adults who suffer from both conditions. The…

This pilot study is testing whether transcranial magnetic stimulation (TMS) can help ease PTSD symptoms in veterans. Twenty veterans with moderate to severe PTSD will receive ten sessions of low-frequency TMS over 2–4 weeks. Researchers will also use brain scans and blood tests t…

This study tests whether a new drug called TSND-201 can safely reduce PTSD symptoms in adults. About 300 people with PTSD will receive either one of two doses of TSND-201 or a placebo once a week for 4 weeks, then be followed for 8 more weeks. The goal is to see if the drug helps…

This study looks at whether combining psychotherapy with mind-body practices (like yoga or meditation) helps Veterans with PTSD function better in daily life. About 300 Veterans will be randomly assigned to different types of integrated care for 12 weeks. Researchers will track c…

This study tests a program called SKILLS that focuses on common factors across different mental health conditions, rather than treating each disorder separately. About 60 adults with stable psychiatric diagnoses will take part. The goal is to see if this approach reduces symptoms…

This study is testing a new type of talk therapy called Process-Based Therapy (PBT) for people with anxiety. Unlike standard treatments, PBT adapts techniques from different therapies to target each person's specific struggles. Ten adults with moderate-to-severe anxiety will try …

This study is testing a type of talk therapy for people who have both HIV and PTSD. The therapy helps people understand how trauma affects their emotions and relationships. The goal is to see if this therapy is helpful and acceptable for this group. About 20 adults with HIV and P…

This small early study tests whether a gentle brain stimulation technique called temporal interference (TI) can safely reduce PTSD symptoms in 5 adults. Participants will receive TI stimulation and have their brain activity measured with MRI, MEG, and EEG. The goal is to see if s…

This study looks at mothers who feel severe pain during a C-section despite spinal or epidural anesthesia. It compares giving general anesthesia versus extra pain medicine to see which better prevents post-traumatic stress disorder (PTSD). The goal is to find a way to reduce trau…

This study tests whether a type of talk therapy called Exposure and Response Prevention (ERP) can improve daily functioning and quality of life in veterans with obsessive-compulsive disorder (OCD). About half of the 160 participants also have post-traumatic stress disorder (PTSD)…

This early study tests whether a surgically implanted device that stimulates the vagus nerve can boost the effects of talk therapy for people with chronic PTSD. Twenty adults who have not gotten better with standard treatments will receive either active or sham stimulation alongs…

This study tests a short, 3-session program called MERA (Manage Emotions to Reduce Aggression) for veterans with PTSD who struggle with impulsive aggression. The program teaches skills to manage emotions better, with the goal of reducing aggressive outbursts and preparing veteran…

This study tests whether adding a nerve block injection (stellate ganglion block) to standard talk therapy (cognitive processing therapy) helps reduce PTSD symptoms more than either treatment alone. About 270 adults with PTSD will be assigned to one of three groups: combination t…

This study tests whether an 8-week virtual reality adventure exergaming program can improve physical activity, mood, and thinking in women veterans aged 18-45. Participants will play VR games that involve movement, and researchers will track changes in depression, anxiety, and PT…

This study offers two proven trauma therapies—Trauma-Focused CBT and Trauma Systems Therapy—to children aged 5-17 with PTSD and their families. Researchers want to see how well these treatments work when children also face stress from racial trauma and adapting to a new culture. …

This study tests a culturally adapted cognitive-behavioral therapy (CBT) program for Venezuelan migrants in Lima, Peru, who struggle with anxiety, depression, or PTSD. The intervention is delivered remotely by trained lay providers over 6 to 12 weekly sessions. The goal is to see…

This study tests whether a short, evidence-based therapy for PTSD (Written Exposure Therapy) can be effectively delivered by community health workers to pregnant women. The goal is to make treatment more accessible and reduce PTSD symptoms during pregnancy and after childbirth. A…

This study tests two behavioral treatments—cognitive behavioral therapy (CBT) and mindfulness—to help people with traumatic brain injury (TBI) sleep better and feel less stressed. 360 veterans and service members with mild to moderate TBI, insomnia, and PTSD symptoms will receive…

This study tests a new anonymous online therapy program called Restory for people with PTSD after sexual abuse. It is designed for 140 adults who have experienced sexual violence at least one month ago. The therapy uses a type of talk therapy done over the internet, and the goal …

This study looks at whether adding a peer support program (WoVeN) to a self-help version of Cognitive Processing Therapy (CPT) helps women veterans with PTSD feel better and improve their mental well-being. About 100 women who have served in the U.S. military and have PTSD sympto…

This study tests whether a single dose of MDMA, given alongside two weeks of daily exposure therapy, can reduce PTSD symptoms more than therapy alone. About 95 adults with PTSD will take either MDMA or a placebo during one therapy session. Researchers will check symptom changes o…

This study tests whether an app-based therapy called A-EMDR can help people who have both PTSD and substance use disorders. Twenty-four adults will use the app three times a week for four weeks, while researchers track changes in PTSD symptoms and substance use. The goal is to se…

This study compares a standard mobile cognitive behavioral therapy (CBT) program to a personalized version that teaches skills faster. About 100 adults aged 18-25 with anxiety, depression, or bipolar disorder will use the Maya app for 20 minutes, twice a week, for six weeks. The …

This study is testing a mobile app called MAYA that teaches cognitive behavioral therapy (CBT) skills to help older adults manage anxiety and depression. About 60 participants aged 40 and older with an anxiety or depressive disorder will use the app for at least 20 minutes, twice…

This early-stage trial tests whether giving psilocybin (the active ingredient in magic mushrooms) in a group setting is safe and feasible for people with PTSD. 36 participants, including veterans, first responders, and survivors of sexual violence, will receive two group dosing s…

This study tests whether a simple injection of dextrose (sugar water) into the neck can reduce symptoms like anxiety, brain fog, and depression in people with PTSD who haven't improved after trying multiple medications and therapies. About 50 adults will receive either the dextro…

This study tests whether a week of accelerated brain stimulation (25 sessions over 5 days) can quickly reduce PTSD symptoms. It involves 132 adults with PTSD, including those with traumatic brain injury. The goal is to see if this fast-paced treatment works better than a placebo …

This study tests if trauma-adapted yoga, added to usual care, can improve mental health and quality of life for 180 teens diagnosed with ADHD or PTSD. Participants will be randomly assigned to a yoga group or a waiting list. The study also explores if online yoga is a feasible op…

This study tests whether a special computer-based brain training program can help adults with PTSD improve memory, attention, and daily functioning. Participants will be randomly assigned to either the brain training program or regular computer games, both with group discussions,…

This study looks at whether a therapy called prolonged exposure, given through video calls, can help people with both opioid use disorder and PTSD. About 135 adults on stable medication for opioid use will take part. The goal is to see if this approach improves therapy attendance…

This pilot study tests whether a trauma-focused therapy (TF-CBT) adapted for autistic youth is practical and well-received in community mental health centers. About 24 autistic children and their therapists will participate. The goal is to see if the therapy is acceptable and fea…

This study tests whether giving cognitive behavioral therapy (CBT) in person, via video, or a mix of both works best for children aged 5-18 with anxiety or OCD. About 500 kids will be randomly assigned to one of three delivery methods. The goal is to find out which approach impro…

This study tests whether a type of talk therapy called prolonged exposure therapy, plus small financial rewards for attending sessions, can reduce PTSD symptoms in pregnant women. Thirty pregnant women with PTSD will receive weekly therapy for 12 weeks. Researchers will measure s…

This pilot study tests whether VA chaplains can deliver a program to help veterans struggling with moral injury—feelings of guilt, shame, and isolation after traumatic events. Twenty veterans receiving mental health care will take part in up to 12 chaplain-led sessions focused on…

This study explores whether teaching people emotion regulation skills tailored to their individual needs works better than a one-size-fits-all approach. Researchers will enroll 390 adults with emotional difficulties, such as depression, anxiety, or PTSD, and assign them to practi…

This study tests whether EMDR, a therapy that uses guided eye movements, can help people with PTSD caused by a heart attack. Sixty adults who had a heart attack and developed PTSD will receive eight weekly EMDR sessions. The goal is to see if EMDR reduces PTSD symptoms and might …

This study tests a non-invasive device that sends mild electrical pulses to the ear to stimulate the vagus nerve. Researchers want to see if it can improve attention and memory in 30 veterans with traumatic brain injury, depression, or PTSD. Participants will try both the real st…

This study is testing a web-based program called Calm Moms for pregnant veterans who have experienced trauma and are feeling anxious, stressed, or down. The program uses proven techniques to help manage these symptoms and is tailored to the unique concerns of pregnancy. About 36 …

This study tests whether transcranial magnetic stimulation (TMS) can help teens aged 12-20 who still have PTSD symptoms after finishing trauma-focused therapy. About 20 participants will receive 10 TMS sessions over a month. The goal is to see if TMS is safe and acceptable, and t…

This study tests a two-week intensive outpatient treatment for people with PTSD, combining prolonged exposure and EMDR therapy. Up to 42 participants will receive daily therapy sessions and be followed for 12 weeks. Researchers will measure changes in PTSD symptoms, quality of li…

This study tests whether Written Exposure Therapy (WET), a brief talk therapy for PTSD, works for veterans who also have serious mental illness like bipolar disorder or schizophrenia. Researchers will enroll 48 veterans to see if the therapy is feasible and acceptable. The goal i…

This pilot study tests whether a short, video-based sleep therapy can help prevent PTSD and depression in people who recently had a car accident. Twenty adults at high risk for PTSD will receive either the sleep therapy or a control session over three weeks. The goal is to see if…

This study tests a device called Prism, which uses EEG to measure brain activity and trains users to calm a part of the brain linked to stress. Researchers want to see if it is safe and helpful for 45 adolescents aged 12-21 with PTSD, when used alongside their usual therapy. The …

This study tests a digital program called BSHAPE designed to help immigrant women who have experienced violence and suffer from PTSD or depression. The program includes education, skill-building, and mindfulness exercises. Researchers will compare it to a general wellness program…

This study tests whether a drug called pimavanserin can improve sleep in veterans with post-traumatic stress disorder (PTSD) who also have insomnia. About 60 veterans will receive either the drug or a placebo for 8 weeks. The goal is to see if it reduces insomnia severity and imp…

This study tests whether giving oxytocin nasal spray before couples therapy can help veterans with PTSD feel better and improve their relationships. About 240 veterans and their partners will take part. Half get oxytocin, half get a placebo, and all receive eight sessions of brie…

This study tests whether adding an unexpected element (like singing) during memory reactivation, combined with the drug propranolol, can reduce physical stress responses to traumatic memories in people with PTSD. Eighty adults with trauma history will be randomly assigned to stan…

This study tests whether a nerve block (stellate ganglion block) or the drug ketamine, alone or together, can reduce headaches and PTSD symptoms in people who have had a traumatic brain injury. About 175 adults will receive one of four treatments, including sham procedures, to se…

This study tests whether adding a group-based stabilization and skill-training program to regular individual therapy helps people with long-lasting post-traumatic stress recover better. About 160 adults receiving outpatient mental health care will take part. Half will get the com…

This study tests if a smartphone app called Sidekick can help teenagers with anxiety disorders practice exposure exercises between therapy sessions. About 46 teens aged 13-18 will use the app alongside their usual outpatient treatment. The goal is to see if the app is practical, …

This study tests a program called NurseNET, where nurses are trained to provide a short-term trauma therapy for PTSD. The goal is to make treatment easier to access for people who see their primary care nurse. Researchers will enroll 100 adults with PTSD symptoms and measure if s…

This study looks at whether group therapy using EFT (Emotional Freedom Techniques) and CBT (Cognitive Behavior Therapy) can reduce PTSD symptoms in veterans and their family members. About 100 participants will attend group sessions and have their symptoms checked before, right a…

This study tests a handheld device called gammaCore that gently stimulates the vagus nerve in the neck, aiming to reduce PTSD symptoms. About 40 adults with PTSD will use the device at home for 12 weeks. Researchers will track symptom changes and safety to see if this approach co…

This study tests two types of online cognitive behavioural therapy (CBT) for Canadian public safety personnel (like police, firefighters, and paramedics) who have symptoms of PTSD, anxiety, or depression. Participants can choose between a therapy focused on PTSD or one that cover…

This study tests whether adding booster sessions and homework reminders to a short psychological program (PM+) can further reduce stress, PTSD, and other mental health problems in refugees and asylum seekers. About 1,200 participants in Switzerland will receive the enhanced suppo…

This study looks at whether adding morning bright light therapy to cognitive training can improve thinking, daily function, and sleep in 144 veterans who have both mild traumatic brain injury and PTSD. Participants will receive either the light therapy or a placebo light device. …

This study tests whether adding a trauma-focused therapy called EMDR to usual care can help reduce trauma symptoms in people with schizophrenia spectrum disorders. Many people with these conditions have experienced trauma, which can make their illness worse, but trauma treatment …

This study tests whether a type of magnetic brain stimulation called iTBS can help people with PTSD. Researchers will give 140 adults either real or fake (sham) stimulation to see if it reduces symptoms like flashbacks and anxiety. The goal is to find a new, non-drug treatment op…

This study tests whether ear acupuncture, combined with mindfulness therapy, can reduce emotional distress in active-duty service members and veterans with PTSD. Sixty-six participants will receive either mindfulness therapy alone or mindfulness plus a one-time ear acupuncture tr…

This study tests whether adding cognitive processing therapy (CPT) to standard relapse prevention (RP) helps people with both PTSD and alcohol use disorder more than RP alone. About 200 adults with moderate to severe alcohol use disorder and current PTSD will receive either CPT+R…

This study is testing whether adopting and training a shelter dog can reduce PTSD symptoms and improve mental health in veterans. 120 veterans with self-reported PTSD or other mental health conditions will attend eight one-hour dog training sessions over 10 weeks. Researchers wil…

This study tests whether a drug called MDMA (often known as ecstasy) can boost the effects of a specific type of talk therapy for PTSD in veterans. Twenty veterans will receive one MDMA session along with 12 prolonged exposure therapy sessions. The goal is to see if this combinat…

This study tests two simple early treatments—writing about the experience (Written Exposure Therapy) and guided breathing exercises (Capnometry Guided Breathing)—to see if they can reduce PTSD symptoms in new mothers after a traumatic childbirth. About 70 women who recently gave …

This study tests two treatments for insomnia in veterans who also have PTSD. One is a brief behavioral therapy focused on sleep habits, and the other is a relaxation technique. Researchers want to see which one improves sleep and daily life more, and if benefits last over time. A…

This study looks at whether different levels of exercise can help people with PTSD remember fear-reduction lessons better. 200 adults with PTSD will do a 3-day fear learning and extinction task, then either rest or do light, moderate, or high-intensity exercise. The goal is to se…

This study tests a treatment called SMART, which uses movement and body awareness to help adults with PTSD. 80 participants will attend 8 sessions and be assessed before, after, and 3 months later. The goal is to see if this approach reduces PTSD symptoms and improves body awaren…

This study tests whether adding a digital mindfulness program to usual care helps adults aged 18-65 recover from emotional disorders like depression, anxiety, OCD, PTSD, and eating disorders. Participants attend online group sessions and use a WeChat mini-program for daily exerci…

This study tests whether a special type of sleep therapy, adapted for trauma, can help women veterans with both insomnia and PTSD feel more ready to engage in PTSD treatment. About 100 women veterans will be randomly assigned to either the sleep therapy or a general education pro…

This study tests a new, single-session therapy called PATH-SS for people struggling with PTSD or depression after a sexual assault. Researchers want to see if this brief treatment reduces distress and is helpful to participants. The study involves 45 adults in Ohio who experience…

This study tests whether trauma-focused therapy delivered via telehealth can reduce PTSD symptoms in underserved youth aged 7-18 in Puerto Rico. Eighty participants who have experienced trauma and have significant PTSD symptoms will receive the therapy remotely. The goal is to se…

This study tests whether low-intensity focused ultrasound (LIFU) can calm overactive brain areas linked to PTSD in frontline healthcare workers. Sixty-six participants will receive either real or fake ultrasound to the brain's cingulate cortex. Researchers will measure changes in…

This study tests whether gentle chest vibration or breath focus exercises can reduce symptoms of dissociation in people who have experienced trauma. Researchers will measure changes in brain activity and self-reported symptoms over 8 sessions. The goal is to understand if these s…

This study tests an internet-delivered cognitive behaviour therapy (ICBT) course designed specifically for public safety personnel (like police, firefighters, paramedics) who experience anxiety, depression, or PTSD. The 164 participants will be randomly assigned to different ways…

This study compares two types of talk therapy for PTSD caused by military sexual trauma: exposure therapy and interpersonal therapy. Researchers want to see if interpersonal therapy works just as well as exposure therapy, which could give survivors more options. The trial will en…

This study compares a 3-session couples program (Brief Relationship Checkup) to standard individual care for 360 veterans and their partners who have relationship and mental health concerns. The goal is to see which approach better reduces suicide risk factors by improving relati…

This study tests whether a non-medication sleep program (CBT-I) can improve sleep, PTSD symptoms, and heart health in older adults with PTSD who still have sleep problems after PTSD therapy. About 167 veterans aged 50 and older will receive PTSD therapy first, then the sleep prog…

This study tests a program called SUPERCEDE, which provides intensive case management to veterans who are at risk for suicide and receive care both from the VA and outside community providers. The goal is to improve care coordination, reduce suicidal thoughts, and improve daily f…

This pilot study tests whether adding ear acupressure (small seeds taped to ear points) to standard nicotine patches or gum can reduce cravings, withdrawal symptoms, and anxiety in psychiatric inpatients who must stop smoking during their hospital stay. Sixty participants will be…

This study tests whether a sublingual tablet (TNX-102 SL) can reduce acute stress symptoms and prevent long-term PTSD in adults who come to the emergency room after a car crash. 180 participants will receive either the drug or a placebo for two weeks, starting in the ER. Research…

This study tests whether giving fluoxetine (Prozac) immediately after a serious injury can prevent depression, PTSD, and reduce pain and opioid use. About 200 adults with fractures or other bodily trauma will receive either fluoxetine or a placebo during their hospital stay. The …

This study tests whether a program that improves how ICU staff care for patients can lower discomfort and reduce the risk of PTSD after leaving the hospital. About 1,242 adults who have been in the ICU for at least three days will take part. The program includes better communicat…

This study tests a new therapy called AMBET (Acceptance- and Mindfulness-Based Exposure Therapy) for treating PTSD in people who survived a cardiac arrest. About 90 adults will be randomly assigned to either AMBET or a standard talk therapy (PCT) for 12 weeks. Researchers will tr…

This study aims to find out which parts of behavioral therapy work best for children aged 8-17 with PTSD after a traumatic event. Researchers will compare different therapy components, like emotion regulation and exposure, to a placebo. 200 children and their caregivers will part…

This study tests a counseling program for caregivers of children hospitalized for a traumatic injury like burns or a car accident. The goal is to reduce PTSD and depression in both the caregiver and child. 24 caregiver-child pairs will be randomly assigned to either the counselin…

This study tests whether a 5-day intensive version of prolonged exposure therapy can treat PTSD as effectively as the standard 15-week approach. 140 adults with PTSD will be randomly assigned to either the intensive format or weekly sessions. Researchers will also look at cost-ef…

This study tests whether a 2-week, fully remote program combining mild brain stimulation (tDCS) with prolonged exposure therapy can reduce chronic pain and PTSD symptoms. About 146 adults with both conditions will receive either real or sham stimulation alongside therapy, all fro…

This study tests whether a low dose of clonidine, a drug usually used for high blood pressure, can improve sleep and reduce PTSD symptoms in veterans. About 32 veterans with PTSD will take a flexible dose of clonidine nightly for 6 weeks. Researchers will track changes in sleep q…

This study is testing whether adding a brief writing exercise (AWARE) to standard PTSD therapies like cognitive processing therapy (CPT) or prolonged exposure (PE) can improve patient-therapist communication and treatment outcomes. Researchers will enroll 54 adults with PTSD, fir…

This study tests whether adding special memory-support techniques to a standard PTSD therapy (Cognitive Processing Therapy) helps veterans learn and remember the therapy content better. About 100 adults with PTSD will take part. The goal is to see if better memory of therapy lead…

This study tests a new EEG neurofeedback system called Prism for treating PTSD in 250 US veterans and civilians. Participants do 15 sessions of Prism training over 8 weeks, plus two booster sessions. The goal is to see if Prism reduces PTSD symptoms more than a sham (fake) traini…

This study tests whether a newer type of talk therapy called transdiagnostic metacognitive therapy (tMCT) works better than standard cognitive-behavioral therapy (CBT) for people with generalized anxiety, social anxiety, or PTSD. About 86 adults in Sweden will receive either tMCT…

This study tests a program called Reminder-Focused Positive Psychiatry (RFPP) for teens aged 11-15 with PTSD. The program helps teens reframe traumatic memories in a positive way. Researchers will compare RFPP to a general support group to see if it reduces PTSD symptoms and impr…

This study is testing whether a virtual reality version of a therapy exercise is practical and helpful for adults (ages 18-65) with psychiatric disorders. Participants will try one VR session and answer questions about their experience. The goal is to see if this approach is acce…

This study tests an AI chatbot called Aurora that guides people through creating a personal life story to improve emotional well-being and identity. It includes healthy adults, adults with mental health conditions in residential care, and older adults aged 65+. The chatbot is not…

This study tests whether a single dose of ketamine given during surgery can help adults with serious orthopedic trauma recover better. Researchers want to see if it reduces pain, lowers the need for opioids, and improves symptoms of depression and PTSD. Ninety participants will b…

This study tests a brief group therapy that teaches people to better understand their own and others' thoughts and feelings (called mentalization). One hundred adults with anxiety or depression will be randomly assigned to this new therapy or to standard group therapy. Researcher…

This study tests a special type of talk therapy called Multi-Modal Cognitive Processing Therapy (MMCPT) for people with posttraumatic stress disorder (PTSD). Sixty adults with PTSD will either receive 12 weekly therapy sessions or standard care. Researchers will track changes in …

This study tests a nerve block procedure called bilateral cervical sympathetic block (BCSB) in 75 Special Operations Veterans with PTSD, anxiety, or traumatic brain injury. The procedure uses a numbing medicine to calm overactive nerves. Some participants also receive talk therap…

This study tests a brief, two-session program for family members of Veterans with PTSD. The goal is to see if this family support helps Veterans stay in their regular PTSD therapy longer and have fewer symptoms. About 200 Veterans and their family members will take part. If it wo…

This study is testing a type of talk therapy called Emotion Regulation Therapy (ERT) delivered over video for people in New York who struggle with worry, overthinking, or being hard on themselves. The goal is to see if the therapy helps people better manage their emotions and fee…

This study tests a 6-session psychoeducation program for people who have experienced sexual violence. The goal is to see if the program improves their quality of life, self-esteem, and mental well-being. Researchers will enroll 60 participants from a hospital clinic in France.

This study tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can reduce symptoms of post-traumatic stress disorder (PTSD). About 72 adults with PTSD will receive 60 treatments over 12 weeks, and researchers will track their symptoms for up t…

This study tests a stepped-care approach to help more people with PTSD get treatment. Participants start with an online skills program (webSTAIR) and can step up to brief therapy sessions if needed. The goal is to improve access, engagement, and symptom relief in routine primary …

This early-stage study at Yale is testing whether a single 25 mg dose of psilocybin is safe and tolerable for people whose daily life is impaired by mood, anxiety, trauma, or addiction symptoms. Fifty participants will receive the drug openly (everyone knows they get it) and be f…

This study tests a special mental health program for people who have been in the ICU. It includes coaching, digital tools, and psychiatric support to help with anxiety, depression, and PTSD. The goal is to see if this program works better than usual care. About 150 adults who vis…

This study tests whether group-based MDMA-assisted therapy works as well as individual sessions for people with PTSD linked to the October 7, 2023 events. 168 participants will receive MDMA in either a group or individual setting, along with therapy sessions. The goal is to see i…

This pilot study tests a behavioral health program designed to support family members of ICU survivors. The program includes telehealth check-ins and a digital platform to track mood and stress. Researchers want to see if this approach is practical and helpful for reducing anxiet…

This early-stage study tests whether psilocybin from whole mushrooms can safely help adults with PTSD. Up to 24 participants will eat dried mushrooms in chocolate and be monitored for side effects and symptom changes. The goal is to gather safety data and see if this approach mig…

This study tests a new type of talk therapy for veterans and service members who have both PTSD and a mild or moderate traumatic brain injury. The therapy focuses on relaxation, stress management, and problem solving instead of asking patients to relive their trauma. The goal is …

This study tests a program called Mental Gym® that uses a smartwatch and phone app to help combat veterans with PTSD. About 80 veterans will either start the program right away or wait a few months. The goal is to see if daily biofeedback exercises and group support can reduce PT…

This study tests a mobile app called Blueprint that teaches coping skills to people who survived a serious illness in the ICU. Many survivors face anxiety, depression, and PTSD, but mental health care is hard to access. The app aims to help them manage these symptoms on their own…

This pilot study tests a 12-week workshop called STEP-Home-SP for veterans who recently left military service. The workshop teaches emotional regulation and problem-solving skills to help with reintegration and reduce suicide risk. Researchers will enroll 120 veterans to see if t…

This pilot study is testing whether a therapy called EMDR (eye movement desensitization and reprocessing) can help reduce post-traumatic stress and psychological distress in people with advanced thyroid cancer. The study will enroll 25 participants who have cancer and PTSD sympto…

This study tests whether a small device that gently stimulates a nerve in the neck can reduce PTSD symptoms in veterans. 80 veterans will use the device at home twice a day for three months. Researchers will measure changes in brain activity, heart function, and PTSD symptoms com…

This pilot study tests a new way to deliver trauma-focused therapy to teens with PTSD. It combines therapist-led video sessions with a mobile app for self-paced exercises. Researchers want to see if this blended approach is feasible and acceptable compared to standard therapy. Ab…

This study aims to redesign Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) so it works better in schools. Researchers will work with school counselors and students aged 7-19 to make the therapy easier to use and more engaging. The goal is to help more young people get effec…

This study tests a stepped care approach that uses complementary health treatments (like acupuncture or yoga) for people with both chronic pain and PTSD. About 60 adults from two primary care clinics will either receive this stepped care or their usual treatment. Researchers want…

This study tests whether adding a brief crisis coping strategy (Crisis Response Planning) to a standard talk therapy (Cognitive Processing Therapy) can lower suicidal thoughts and behaviors in veterans with PTSD. About 190 active-duty service members and veterans with PTSD and re…

This study tests a personalized, noninvasive brain stimulation technique called TMS for people aged 18–65 with chronic symptoms after a mild concussion or traumatic brain injury. Symptoms like headache, dizziness, brain fog, and anxiety can last for months. Participants will rece…

This Stanford study tests whether having a dream while under anesthesia can reduce PTSD symptoms. In a small Phase 2 trial, 42 adults with PTSD will receive either deep sedation to trigger dreaming or light sedation without dreaming. Researchers will compare changes in PTSD sever…

This pilot study tests a new 12-week group therapy program called BEAR-SI for women aged 18-75 who have experienced interpersonal trauma and currently have suicidal thoughts. The program combines psychological skills, education about trauma, and physical self-defense training. Th…

This study looks at how well and how safely a new sleep medication, lemborexant, works for people who have both a mental health condition and trouble sleeping. About 121 adults will take the drug for 8 weeks, and researchers will track changes in their sleep quality and any side …

This study tests whether a short writing therapy called Written Exposure Therapy (WET) can help veterans who have both posttraumatic stress disorder (PTSD) and a substance use disorder. About 170 veterans will complete five writing sessions about their trauma. The goal is to see …

This study tests an internet-based therapy called acceptance and commitment therapy (iACT) for people with both PTSD and chronic pain. Forty adults will either receive the therapy immediately or join a waitlist. The program includes mindfulness, value-based exercises, and written…

This study tests whether a group therapy program (GTEP) can help reduce trauma symptoms in people who had a traumatic birthing experience. Ten participants will join online sessions and complete questionnaires about their symptoms and well-being. The goal is to see if this approa…

This study tests whether cannabidiol (CBD), a compound from cannabis, can reduce PTSD symptoms and improve thinking problems in people with PTSD, including those who also have a mild traumatic brain injury. 120 participants will receive either a low or high dose of CBD or a place…

This study tests a noninvasive technique called Energy Resonance by Skin Stimulation (ERCS) to reduce stress in patients recovering after an ICU stay. 38 adults in a post-ICU rehabilitation unit will receive two ERCS sessions a week apart. Researchers will measure stress levels b…

This study tests a new way to help veterans with PTSD stop smoking. It combines counseling, nicotine gum, and a noninvasive brain stimulation called TMS. Researchers want to see if this approach is practical and helps veterans stay smoke-free for at least 3 months. About 50 veter…

This study looks at whether watching Netflix or Disney shows in a small group for 90 minutes each week, over 6 weeks, can improve emotional awareness and reduce anxiety and depression. About 70 adults who have been in mental health treatment for at least 6 months will take part. …

This study tests whether combining virtual reality therapy with a mild brain stimulation technique can help veterans and civilians in Ukraine cope with PTSD. Participants attend 10 therapy sessions using VR goggles to safely face traumatic memories, with some also receiving a gen…

This study tests a group therapy method called I-Reconstruction to see if it lowers anxiety in adults. Thirty-six participants will attend ten weekly online sessions and complete questionnaires about their anxiety and mood. The researchers will compare them to a group receiving u…

This pilot study tests whether trauma-focused therapy delivered via videoconference is feasible and acceptable for adults with PTSD or complex PTSD. Researchers will enroll 13 people from community mental health services in Chile. The study focuses on whether people will join, st…

This study tests whether listening to 15 minutes of frequency-filtered classical music before each cognitive processing therapy session can improve PTSD symptom relief. 100 adults with PTSD or subthreshold PTSD will be randomly assigned to hear either filtered or unfiltered music…

This study is testing two different ways of delivering intensive cognitive behavioral therapy (CBT) to veterans with PTSD and anxiety disorders. One format is individual therapy over two weeks, and the other is group therapy over two days. Both are compared to standard care. The …

This study tests a new form of transcranial magnetic stimulation (TMS) for post-traumatic stress disorder (PTSD). Unlike standard TMS, which takes 6-7 weeks, this accelerated version delivers 10 sessions per day for 5 days. Researchers will enroll 40 adults with PTSD to see if ac…

This study tests a therapy called Targeted Cognitive Training (TCT) for veterans with serious mental illnesses like schizophrenia, bipolar disorder, or PTSD. The goal is to improve thinking skills and daily functioning by using EEG brain scans to identify who will benefit most. A…

This study tests whether Cognitive Processing Therapy (CPT), a talk therapy used in the community, can reduce PTSD symptoms and rule-breaking in incarcerated men and women. About 900 participants from 6 prisons will attend 8–12 therapy sessions over up to 24 weeks. Researchers wi…

This study tests a 12-week group therapy program called ECCCLORE for people who have both post-traumatic stress disorder (PTSD) and addiction. The program combines skills for managing emotions, distress, and relationships. Researchers want to see if it is feasible and acceptable …

This study tests a drug called CORT108297, which blocks the stress hormone cortisol, as a short-term treatment for PTSD in veterans. Forty veterans with PTSD will take either the drug or a placebo daily for one week. The goal is to see if it reduces PTSD symptoms and to check its…

This study tests whether adding augmented reality (AR) to standard exposure therapy helps U.S. military personnel with PTSD more than therapy alone. Forty veterans or active-duty members will be split into two groups: one gets traditional therapy plus AR, the other gets therapy o…

This study tests a new type of talk therapy called Identity-Based Transdiagnostic Therapy (IBTT) for young adults with anxiety or depression. It compares IBTT to a well-known therapy called the Unified Protocol (CBT-based). The goal is to see if IBTT is more engaging and effectiv…

This study tests a multi-sensory therapy called Heal, which uses calming sounds, gentle vibrations, and soft lighting to help detained youth (ages 12-18) manage their emotions before counseling sessions. The goal is to see if this brief, non-verbal intervention improves emotional…

This study tests whether sailing can help people with psychiatric disorders feel better. Forty adults in France will either take sailing lessons or continue their usual care. Researchers will measure changes in quality of life, mental well-being, and self-esteem to see if sailing…

This study tests whether a guided therapy using psilocybin (the active ingredient in magic mushrooms) can safely help US Veterans with PTSD. Fifteen participants will receive two psilocybin sessions combined with talk therapy. The goal is to reduce PTSD symptoms and improve long-…

This study tests a new therapy called the Reconsolidation of Traumatic Memories (RTM) Protocol for people with PTSD in Ukraine. The goal is to reduce distressing symptoms like flashbacks and anxiety without requiring patients to relive their trauma in detail. The study will invol…

This study looks at whether a smartphone app called PE Coach can help veterans with PTSD do better in a proven type of talk therapy called prolonged exposure. About 124 veterans will be randomly assigned to receive therapy with or without the app. The goal is to see if the app im…

This study tests whether adding a noninvasive brain stimulation technique called rTMS to a brief writing therapy (WET) can better reduce PTSD symptoms in veterans. About 98 veterans with PTSD will receive either real or fake rTMS before their writing sessions. Researchers will me…

This study looks at whether art therapy can help active-duty military and recent veterans who have PTSD symptoms. Forty participants will attend 11 sessions over 6-8 months, including art therapy with a certified therapist and two MRI brain scans. The goal is to see if art therap…

This study tests whether the stimulant medication methylphenidate (Ritalin) can improve PTSD symptoms and thinking problems like poor memory and concentration in 70 Veterans. Each participant will switch between the drug and a placebo every 4-5 weeks over 20 weeks, without knowin…

This study tests whether a single dose of ayahuasca or esketamine can reduce symptoms of posttraumatic stress disorder (PTSD). Ten adults with PTSD will receive one of the two drugs in a double-blind design. The goal is to see if either substance can provide rapid relief from PTS…

This study tests whether a smartphone app called OTX-601 can help reduce symptoms of post-traumatic stress disorder (PTSD) in adults. Forty people with PTSD will use either the active app or a placebo version for several weeks. Researchers will track changes in PTSD symptoms usin…

This pilot study tests a wearable brain stimulation device called tACS for treating anxiety in up to 40 veterans under age 70. The device delivers low-intensity electrical pulses through scalp electrodes and can be used at home after an in-office training session. Over 8 weeks, r…

This study tests whether 5 group sessions teaching mind-body skills can reduce PTSD symptoms and emotional problems in 120 adolescents aged 11-17 in Gaza who have experienced war-related trauma. Participants are randomly assigned to either the mind-body group or a control group, …

This study compares a new type of therapy that combines computer exercises with therapist sessions (blended CBT) to standard prolonged exposure therapy for PTSD. About 160 adults with PTSD will receive one of the two treatments at outpatient clinics in Sweden. The goal is to see …

This study tests a new training program for veterans who have both mild traumatic brain injury (mTBI) and PTSD. The training combines exercises to recognize emotions in faces and voices with attention training, since paying attention is key to understanding emotions in daily life…

This study is testing whether a type of talk therapy called metacognitive therapy (MCT) can be delivered in a group setting for people with post-traumatic stress disorder (PTSD) in regular psychiatric care. The goal is to see if it is practical and acceptable to patients, and to …

This study aims to find the best strategies for veterans with PTSD who aren't helped by their first treatment. Researchers will test a flexible version of Cognitive Processing Therapy and text message reminders to encourage homework completion. The goal is to match the right type…

This Phase 3 trial tests whether Silexan, a lavender oil extract available over-the-counter, can reduce PTSD symptoms in adults. 278 participants will take Silexan or a placebo daily for 12 weeks alongside their usual treatments. The goal is to see if this well-tolerated suppleme…

This study is creating and testing a short, online therapy program for LGBTQ+ people who have experienced trauma and drink alcohol. In the first phase, participants share their thoughts to make the program more helpful and welcoming. In the second phase, some participants can try…

This study tests a web-based program called webSTAIR, which teaches emotion regulation and relationship skills, for female veterans who have experienced military sexual trauma or intimate partner violence and also have a brain injury. The goal is to see if it helps them manage em…

This study tests a short intervention called iCOVER, designed to help people quickly regain focus and calm after an acute stress reaction. The intervention takes just 60-120 seconds and can be given by peers or medical staff. Researchers will enroll 450 adults in an emergency dep…

This study tests a quick, 5-day group therapy program for active-duty military and veterans who struggle with PTSD, insomnia, and nightmares. 160 participants will receive either cognitive-behavioral therapy or sleep education, both combined with a proven PTSD writing therapy. Th…

This study tests a therapy called HOPE for people who have both opioid use disorder and PTSD. Participants must already be on medication for opioid use disorder (like Suboxone or methadone). Over 10-12 weeks, they will attend therapy sessions and complete surveys to see if their …

This study tests whether an online, therapist-guided program for insomnia can also reduce anxiety symptoms. 98 adults with both chronic insomnia and anxiety will either start the program immediately or after a delay. The program includes sleep education, behavioural strategies, a…

This study looks at whether combining two common therapy techniques—changing negative thoughts and practicing detached mindfulness—works better than using them alone for people with anxiety or depression. Researchers will compare the effects of each technique and their order. The…

This study looks at whether a self-administered technique called alternating bilateral stimulation (like moving your eyes side to side or tapping your shoulders) can make intrusive, distressing memories feel less intense and less vivid. Researchers will enroll 150 adults with sym…

This study tests a new version of a therapy called RTM-C for children aged 6-14 with PTSD. The treatment uses child-friendly language, games, and animated tools to help kids safely replay difficult memories and reduce fear. About 40 children and their parents will take part in up…

This study tests a software program designed to reduce symptoms of post-traumatic stress disorder (PTSD). About 52 adults with PTSD will use the software or a placebo version. Researchers will measure changes in PTSD severity using a standard scale over the study period.

This study tests whether involving a romantic partner in PTSD therapy helps veterans function better in daily life. About 420 post-9/11 veterans with PTSD and their partners will take part. The treatment, called Partnered PE, adds partner support to standard exposure therapy to i…

This study compares two strategies for veterans struggling with Cognitive Processing Therapy (CPT) for PTSD: using CPT skills to work through challenges, or switching to a different therapy called Present Centered Therapy. The goal is to see which approach reduces dropout and imp…

This study tests whether sitting in front of a bright light for 60 minutes each morning can improve sleep in veterans who have had a traumatic brain injury (TBI) and may also have PTSD. About 200 veterans will wear a sleep tracker and fill out questionnaires before, during, and a…

This study looks at whether two types of talk therapy can help people who feel dirty or contaminated inside after a sexual assault. 12 adults with PTSD will try Cognitive Processing Therapy and a self-compassion program. The goal is to reduce PTSD symptoms and the troubling feeli…

This study tests a type of talk therapy called Trauma-Focused Psychodynamic Psychotherapy (TFPP) for veterans with PTSD who haven't gotten better with standard VA treatments. About 75 veterans will be randomly assigned to receive either TFPP or usual care. The goal is to see if T…

This study tests whether a single intravenous dose of allopregnanolone, compared to a placebo, can help people with PTSD better process and reduce the power of traumatic memories. The trial involves 96 adults with chronic PTSD and uses skin conductance and startle responses to me…

This study is testing whether low-intensity focused ultrasound (LIFU) — a noninvasive device that sends sound waves to the brain — can help people with chronic back pain, opioid cravings, and anxiety. Researchers will enroll 25 adults and measure safety, mood, heart rate, and oth…

This early-phase study tests whether a sublingual form of dexmedetomidine (BXCL501) is safe and shows promise for treating alcohol use disorder in people who also have PTSD. Ten heavy drinkers with PTSD will take the drug and be monitored for changes in blood pressure, anxiety, a…

This study tests whether a condensed form of PTSD therapy, called Massed Prolonged Exposure (M-PE), can help people who are also being treated for substance use disorders. About 168 adults will either receive M-PE alongside their usual substance use program or continue with stand…

This study tests whether virtual reality (VR) can help healthcare workers and COVID-19 patients with posttraumatic stress disorder (PTSD). Participants will use VR headsets during 10 therapy sessions over 5 weeks to safely revisit and overcome traumatic memories. The goal is to s…

This study tests a non-invasive device that stimulates the vagus nerve (a key nerve in the body) to see if it can improve memory and reduce PTSD symptoms in veterans with mild traumatic brain injury. One hundred veterans will receive either active stimulation or a sham (fake) tre…

This study tests a computer program called COGENT, designed to improve thinking skills like memory and attention in people with anxiety, depression, or PTSD. 128 adults will be randomly assigned to either the COGENT training or a sham program. Researchers will compare changes in …

This study compares two ways of delivering a combined attention and strategy training program to veterans with mild traumatic brain injury and PTSD. One group receives the training in person, the other via telehealth. The goal is to see if remote delivery works just as well for i…

This study tests a mobile app designed to help veterans with PTSD who struggle with anger. 150 veterans will be randomly assigned to use either the anger-reduction app or a health education app. The goal is to see if the anger app helps more veterans get their anger under control…

This study looks at two short counseling programs for veterans who have experienced intimate partner violence in the past year. One program offers up to 8 sessions covering topics like social support and health effects, while the other is a single session focused on safety and re…

This study tests whether adding memory-support strategies to standard cognitive processing therapy (CPT) helps older veterans with PTSD learn and remember therapy content better. Thirty veterans over age 59 will receive either standard CPT or CPT with extra memory aids. The goal …

This study tests whether providing doula support and care coordination to parents of preterm babies in the NICU can reduce stress, depression, and anxiety. Twenty English-speaking mothers of babies born before 34 weeks are being recruited. The doula helps connect families to ment…

This study is testing whether hyperbaric oxygen therapy (HBOT) can improve thinking, mood, and quality of life in veterans who have traumatic brain injury, PTSD, anxiety, or depression. Fifty-four veterans will receive multiple HBOT sessions in a pressurized chamber while breathi…

This study is testing a new social skills training program for Veterans with serious mental illness (like schizophrenia, bipolar disorder, or PTSD) who are looking for work. The program teaches skills to better understand social cues and handle workplace relationships. Researcher…

This early-stage study at Johns Hopkins is testing whether giving both psilocybin and MDMA together is safe and can help reduce PTSD symptoms in military veterans. Forty veterans with PTSD will receive the drugs in a controlled setting. The study tracks side effects, suicidal tho…

This study tests whether brief, online self-guided programs can help parents of children ages 2-7 better manage their child's anxiety. About 90 parents will be randomly assigned to one of three programs. The goal is to see if these programs reduce how much parents accommodate the…

This pilot study tests whether cognitive behavioral therapy (a type of talk therapy) for PTSD can also reduce the risk of heart disease. Researchers will measure inflammation, heart rate variability, and brain activity in 30 adults with PTSD and heart risk factors. Half will rece…

This study tests a 1-month self-management program for people who have recently received a shock from their implantable defibrillator (ICD). The program includes heart rate monitoring and online modules with phone coaching, aiming to reduce anxiety and prevent PTSD. 60 participan…

This pilot study tests whether a 5-day intensive therapy program can help teens aged 13–17 with PTSD. The program combines trauma-focused therapy, EMDR, physical activity, and parent support. Researchers want to see if it's practical and acceptable in Swedish child psychiatry, an…

This study tests a specific type of acupuncture, called 'External and Internal Dragons,' to see if it can reduce PTSD symptoms in military members and their families. The treatment is designed to help the rational and emotional parts of the brain communicate better, so the emotio…

This study tests whether a medication called RE03 (dexmedetomidine), already used in intensive care, can improve sleep in people with PTSD who have trouble sleeping or nightmares. Twenty-four adults with PTSD will receive either the drug or a placebo in random order, and their sl…

This study tests whether a daily nasal spray of insulin can reduce PTSD symptoms. Twenty adults with current PTSD will receive either insulin or a placebo for several weeks. Researchers will measure symptom changes using a standard PTSD scale.

This study tests whether special breathing exercises can help veterans and others with persistent post-concussion symptoms like headaches, dizziness, and memory trouble. The exercises aim to improve heart rate variability, a sign of how well the nervous system is working. 148 par…

This study tests a prescription wrist device called NightWare that detects when a veteran with PTSD is having a nightmare and gently disrupts it without waking them. Researchers want to see if better sleep from fewer nightmares can also improve blood vessel and heart health. 125 …

This study tests whether brief educational videos delivered by text message can help young people aged 15-25 manage symptoms of post-traumatic stress disorder (PTSD). Participants are randomly assigned to receive the videos right away or after a 5-month wait. The study is fully o…

This study tests whether a computer-based working memory training program can help veterans with PTSD improve their ability to unlearn fear responses. 120 veterans will be randomly assigned to either the training or a sham version. The goal is to see if the training changes brain…

This study tests whether a one-time injection of a local anesthetic into a nerve bundle in the neck (stellate ganglion block) can improve the effects of a type of talk therapy called prolonged exposure for PTSD. The trial involves 140 current or retired military members with PTSD…

This study looks at how exercise training impacts blood vessel function in people with PTSD or generalized anxiety disorder, compared to healthy individuals. Researchers want to understand if harmful substances called oxidants play a role in blood vessel damage. The study involve…

This study investigates whether the quality of parent-adolescent communication at the start of psychiatric inpatient treatment predicts how much symptoms improve six months later. Researchers will track 60 adolescents hospitalized for depression, anxiety, or other mental disorder…

This study at the National Institute of Mental Health screens up to 16,000 people with mood or anxiety disorders, as well as healthy volunteers, to see if they can join other research studies. Participants undergo evaluations like psychiatric interviews, brain scans, and lab test…

This study looks at how a stellate ganglion block injection affects sleep in U.S. service members and veterans with PTSD who are already receiving talk therapy. About 40 participants will wear an EEG headband for three nights before and three nights after the injection to measure…

This study investigates whether a clinical test using lorazepam (Ativan) and brain imaging can identify veterans with PTSD who might benefit from medications that boost GABA signaling. Researchers aim to validate a computational method to distinguish subgroups of PTSD patients ba…

This study compares two ways to help adults with mental health issues get follow-up care. One group gets usual care after an emergency room visit, while the other uses a new system that books a psychiatrist appointment within 48 hours through their general doctor. Researchers wil…

This study aims to describe moral injury—a deep conflict between professional values and workplace reality—among 3,073 healthcare workers in France. Researchers will use surveys to measure moral injury and identify organizational and personal risk factors. The goal is to guide sy…

This study is testing whether a carbon dioxide (CO2) challenge can predict which patients with anxiety, OCD, PTSD, or panic disorder will not respond to exposure-based therapy. Researchers will enroll 600 adults and measure their reaction to breathing CO2-enriched air before star…

This study looks at whether a tool called the Decision Helper helps people with mental health conditions take a more active role in choosing their treatment. About 62 adults in Danish outpatient mental health clinics will have their consultations recorded and analyzed. The goal i…

This study looks at how the brain processes time and attention after losing a loved one to suicide, homicide, or accident. Researchers will measure brain waves in 61 adults who experienced such a loss recently. The goal is to find early signs that may lead to PTSD or depression, …

This study uses a special PET scan tracer to measure a brain protein called PDE4B in people with PTSD or alcohol use disorder. Researchers want to see if levels of this protein differ from healthy individuals. The study involves 160 adults aged 18 to 70 and does not offer treatme…

This study looks at the mental health of 200 teenagers aged 12 to 16 who attend special educational institutes (ITEPs) in France. Researchers will use psychiatric interviews to find out how many have conditions like depression or anxiety. The goal is to better understand their ne…

This study follows 80 cervical cancer patients who receive brachytherapy (internal radiation) to see if they develop post-traumatic stress disorder (PTSD). Participants fill out questionnaires about PTSD, anxiety, depression, quality of life, and sexual health over 5 years. The g…

This study aims to improve suicide prevention for people who move between healthcare and the criminal-legal system. Researchers will link health records, Medicaid data, and jail booking information to identify individuals at risk and coordinate care. Over 1,000 adults with past p…

This study looks at whether a simple rating scale used by doctors right after a traumatic event can predict who will develop post-traumatic stress disorder (PTSD) later. Researchers will follow 241 adults who experienced a trauma in the last 48 hours, tracking their scores and ch…

This study tests a program to help doctors in psychiatric clinics prescribe medications for alcohol use disorder to patients who also have serious mental illness. The program uses an external facilitator to work with clinic staff and overcome barriers to prescribing. The goal is …

This study checks how well a new version of a mental health interview (CIDI 5.0) can identify people who have had depression, anxiety, or PTSD at some point in their lives. Researchers in Hong Kong will interview 300 adults and compare the results with a detailed clinical assessm…

This study looks at whether asking new mothers a few questions within 48 hours of an unplanned C-section can predict who will develop post-traumatic stress disorder (PTSD) related to childbirth. Researchers will follow 420 women for three months, comparing early screening scores …

This study aims to understand why people with post-traumatic stress disorder (PTSD) have a higher risk of heart disease and high blood pressure. Researchers will measure nerve activity and test whether the drug losartan can lower high adrenaline levels during stress. The study in…

This study tests an experimental drug to see if it can fix brain patterns linked to avoiding rewards in people with major depression or anxiety. About 112 unmedicated adults will have brain scans and do decision-making tasks. The goal is to understand how the drug works, not to c…

This study tests whether a phone-based check-in system can improve mental health outcomes for women who have experienced violence. Researchers will call some participants a few weeks after their forensic exam and offer support, while others receive standard care. The goal is to s…

This study is testing whether a non-invasive brain stimulation technique called iTBS, combined with computer-based attention training, can improve focus and daily functioning in people with persistent attention problems after a mild traumatic brain injury (mTBI), with or without …

This study at Yale University is testing whether blocking a specific brain receptor (AMPA) stops ketamine from reducing suicidal thoughts. Thirty adults with depression, bipolar disorder, or PTSD who have current suicidal thoughts will receive either perampanel (an AMPA blocker) …

This study looks at how people with PTSD learn to avoid certain situations, using mild electric shocks and brain scans. Researchers will measure stress responses and brain activity in 300 adults as they learn to avoid shocks by pressing a button. The goal is to understand the bra…

This study looks at how a non-invasive brain stimulation technique called TMS affects the brain's fear circuits. Researchers will test different TMS settings in 250 people with and without PTSD to see how it changes fear-related brain activity and skin responses. The goal is to l…

This study looks at how ketamine works in the brain to relieve depression. Researchers are giving people with hard-to-treat depression either a placebo or a drug called perampanel before a dose of ketamine. They will use brain scans to see if blocking certain brain receptors chan…

This study looks at how a type of talk therapy called Cognitive Processing Therapy (CPT) changes brain circuits related to reward and pleasure in people with PTSD. Researchers will use brain scans to track these changes in 120 participants. The goal is to understand why some peop…

This observational study at Yale University is recruiting 200 people who are already taking part in another trial where they may receive a serotonergic psychedelic (like psilocybin or LSD) or a placebo. Researchers want to understand how these substances change the brain's inform…

This study uses a special PET scan tracer called [11-C]OMAR to measure cannabinoid receptors in the brain. Researchers will compare healthy volunteers to people with schizophrenia, cannabis dependence, PTSD, opioid use disorder, and other conditions. The goal is to understand how…

This study is testing a new family-based program (Fam-AID) for teens aged 13-21 who are getting treatment for substance use and also have anxiety or depression. The program adds extra support for mental health and family involvement to their usual care. Researchers want to see if…

This study looks at how alcohol changes decision-making in people with PTSD, especially when they have to choose between reward and danger. Researchers will give participants either alcohol or a placebo and then scan their brains while they perform a task. The goal is to understa…

This study is testing whether a prebiotic called resistant potato starch can change the gut microbiome in 30 veterans who have both cirrhosis (liver scarring) and PTSD. Participants will take either the potato starch or a placebo (cellulose) for a period, and researchers will mea…

This study looks at how drinking problems and posttraumatic stress disorder (PTSD) together may lead to violence between partners. Researchers will observe 70 couples in a lab and track their daily experiences for 28 days. The goal is to better understand these connections, not t…

This study looks at why women with PTSD have a higher chance of heart disease later in life. Researchers will test if beetroot juice, a natural source of nitric oxide, can improve blood vessel function in 30 premenopausal women who have experienced trauma. The goal is to understa…

This study looks at how different exercise programs affect blood vessel function in people with PTSD or generalized anxiety disorder, compared to healthy individuals. Researchers will measure changes in arm and leg blood vessel dilation after 10 weeks of strength training. The go…

This study looks at how growing up with a heart condition might increase the risk of post-traumatic stress disorder (PTSD). Researchers will survey 1,000 adults with congenital heart disease to find out which experiences—like past surgeries or bullying—are linked to PTSD. They wi…

This study tests a new method to personalize TMS (a non-invasive brain stimulation) dosing for people with PTSD, with or without mild traumatic brain injury. Researchers will use brain imaging (fNIRS) to measure brain activity directly, aiming to replace the current indirect meth…

This study tests whether a device called rTMS, which uses magnetic pulses to temporarily change brain activity, can alter how people with anxiety respond to fearful situations. Researchers will measure brain signals and reactions in 80 adults who recently started anxiety treatmen…

This study looks at whether using a short-acting paralytic drug (succinylcholine) instead of a longer-acting one (rocuronium) can prevent patients from being awake while paralyzed during emergency breathing support. About 3,090 adults on ventilators in emergency departments will …

This study looks at whether a program with a nurse case manager can help people leaving prison visit a doctor or clinic instead of the emergency room. About 488 adults with a history of substance use and a chronic health condition will take part. Some will get extra support from …

This study tests whether using a life history calendar—a simple grid that helps people recall important life events—can improve the accuracy of mental health surveys. Researchers in Hong Kong will ask 2,500 adults about their mental health using either a standard interview or one…

This study tests whether combining a one-time session of brain stimulation (rTMS or electrical scalp stimulation) with emotion regulation training helps people with mood, anxiety, or related disorders better control their emotions. 240 participants will learn either cognitive res…

This study looks at whether a single dose of estradiol (a hormone) can reduce the number of intrusive, unwanted memories that form after a traumatic event. Healthy female volunteers will watch a stressful film and then record any intrusive memories over the next four days. The go…

This study follows 21 adolescents aged 12 to 18 who have experienced trauma and are undergoing trauma-focused cognitive behavioral therapy (TF-CBT). Researchers will regularly measure their PTSD symptoms, along with anxiety and depression, to see how symptoms change over time. Th…

This study aims to validate French versions of two short screening questionnaires: the PHQ-4 for anxiety and depression, and the PC-PTSD-5 for post-traumatic stress disorder. Researchers will enroll 90 adults, both outpatients and hospitalized, to see if these tools work as well …

This study uses non-invasive eye scans (OCT and OCTA) to look for changes in the retina that might be linked to brain diseases like Alzheimer's, Parkinson's, and multiple sclerosis. Researchers aim to find early markers that could help diagnose or track these conditions. The stud…

This study is testing a new questionnaire called PTSD-iMPACT to see how well it measures the ways PTSD can interfere with daily life in children and adolescents. Researchers will include 1,200 participants from Switzerland and Germany, both those with and without PTSD symptoms. T…

This research study collects health information from 10,000 people with brain inflammation conditions like Long COVID, ME/CFS, and autoimmune diseases. Participants use a smartphone app to share symptoms, health history, and wearable data. The goal is to find disease subtypes and…

This study looks at how a stay in the intensive care unit (ICU) affects a person's quality of life and risk of post-traumatic stress disorder (PTSD). Researchers will ask 40 adults who spent more than 48 hours in the ICU to fill out questionnaires about their experience and curre…

This study looks at why people with PTSD have a higher risk of heart problems. Researchers will measure nerve activity and test if two daily therapies—a breathing technique or a mild nerve stimulation device—can calm the overactive nervous system. About 120 veterans with and with…

This study looks at how trauma-focused therapy changes brain connections in teenagers with PTSD. Researchers will use brain scans before and after each phase of therapy to understand which brain networks are involved. The goal is to learn how therapy works in the brain, which cou…

This study looks at how sleep and emotion processing are linked in teenagers with post-traumatic stress disorder (PTSD). Researchers will use a special sleep device to try to improve sleep quality and see if it helps with next-day mood. 180 teens aged 15-18 will take part, comple…

This study looks at how common post-traumatic stress disorder (PTSD) symptoms are in women who have had a miscarriage in the first three months of pregnancy. Researchers will use questionnaires to measure symptoms and recovery stages. The goal is to better identify women who coul…

This study looks at how many women experience post-traumatic stress disorder (PTSD) symptoms after being diagnosed with an ectopic pregnancy. Researchers will use questionnaires to measure symptoms and recovery stages in 200 women. The goal is to better identify those who might n…

This study aims to understand how adolescents with post-traumatic stress disorder (PTSD) experience psychotherapy. Researchers will interview 65 teens aged 12-18, along with their parents and therapists, to explore what helps them feel better. The goal is to learn more about the …

This study looks at whether a recovery-focused program can help people with severe mental illness living in supported housing. About 72 participants will either receive the new program or standard care. The goal is to see if focusing on personal goals improves daily functioning a…

This study explores whether showing combat veterans with PTSD very brief, barely visible images of combat scenes can change their brain activity and reduce fear. Participants will view these images during an fMRI brain scan and rate their fear. The goal is to understand how the b…

This study looks at whether short-term changes in the immune system can alter how people process information and experience fear. Researchers will give some participants a typhoid vaccine (which temporarily activates the immune system) and others a placebo. By measuring physical …

This study aims to understand the brain mechanisms behind fear and anxiety in people with anxiety disorders like PTSD and GAD. Researchers will measure brain activity, heart rate, and skin responses while participants view fear-provoking images or use virtual reality. The study i…

This pilot study is testing whether two established trauma therapies—Prolonged Exposure and EMDR—can be safely used in young adults with psychotic disorders who also have PTSD symptoms. Twenty participants from the OPUS early-intervention program will receive one of the therapies…

This study will use advanced PET/MRI scans to see how exercise affects brain activity and blood vessel inflammation in 10 people with PTSD who also have heart disease or risk factors. Participants will follow a gradually increasing exercise program. The goal is to understand whet…

This study talks to siblings aged 9 to 18 whose brother or sister is in the pediatric intensive care unit (PICU). Researchers want to learn about the siblings' needs and how this experience affects their daily life. They will interview each sibling twice: once during the hospital…

This study looks at how different exercise programs affect blood vessel function in people with PTSD or generalized anxiety disorder. Researchers will compare moderate versus high intensity exercise in 360 participants. The goal is to see if exercise can improve vascular health, …

This study looks at how prolonged exposure therapy helps people with PTSD. Researchers will track 50 adults over 17 weeks, using brain scans, heart rate, and questionnaires before, during, and after treatment. The goal is to understand the mechanisms behind the therapy, not to te…

This study tests a new system to help doctors better screen for and manage PTSD in primary care clinics on Chicago's South Side. About 17,000 adults will take part. The goal is to see if this approach leads to more people being diagnosed and getting the right treatment.

This study uses brain imaging and a single dose of the anti-anxiety drug lorazepam to understand how people with both depression and anxiety disorders process threats differently than those with depression alone. About 165 adults will complete two sessions involving startle tests…

This study tests whether a non-invasive brain stimulation technique called continuous theta burst stimulation (cTBS) can reduce arousal in people with PTSD. Researchers will apply cTBS to a brain region involved in attention and fear processing, then measure startle responses and…

This study explores whether a non-invasive brain stimulation technique called cTBS can disrupt the consolidation of fear memories shortly after a traumatic event. Researchers will use functional MRI and skin conductance responses to measure changes in brain connections and fear r…

This study compares two different screening methods for PTSD in pregnant Black women to see which one better improves mental health, use of prenatal and mental health care, and birth outcomes. About 804 Black women in their first trimester who have experienced at least one trauma…

This study looks at what to do when the first PTSD therapy doesn't work. Researchers will test different proven therapies on 400 adults who didn't respond to initial treatment. The goal is to find out which second treatment works best and create a tool to identify early who might…

This study tests whether a technology called transcranial focused ultrasound (tFUS) can temporarily change brain activity linked to anxiety. Researchers will recruit 40 adults with anxiety disorders who recently started treatment. Participants will undergo brain imaging and then …

This study is testing a program called Coffee and Family Education and Support (CAFES2) for refugee families from Arabic-speaking countries who have recently moved to Chicago. The program is led by trained peers and aims to improve mental health and family relationships. Research…

This study is creating a program called START-VET to help veterans with mental illness or substance use disorders who have recently left prison. Researchers will work with 20 veterans to develop transition materials and tools. The goal is to improve quality of life and reduce cri…

This observational study follows 300 adults receiving strategic psychotherapy—a short-term, goal-focused talk therapy—in private practice. Participants fill out questionnaires about their symptoms and well-being before and after treatment. The goal is to see if this therapy leads…

This study looks at how the brain processes threats in people with PTSD. Researchers will use a mild electrical current (tACS) to gently stimulate brain areas and measure changes in brain activity and anxiety. The goal is to understand the brain mechanisms behind PTSD, not to tes…

This study looks at how the brains of people with PTSD process sensory information differently. Researchers will use a mild electrical current (tACS) applied to the scalp to see if it can change brain activity and reduce feelings of anxiety and hypervigilance. The study involves …

This study is looking for genetic markers linked to a side effect called behavioral activation—feeling overly excited or agitated—that can happen when children and youth take SSRI antidepressants for depression, anxiety, or OCD. Researchers will collect DNA from 160 participants …

This pilot study is testing whether a simple saliva test can help doctors prescribe mental health medications more safely and effectively. 200 adults in Manitoba who are starting or changing psychiatric drugs will provide a DNA sample. The results will be shared with their doctor…

This study tests a stepped care program called the Trauma Resilience and Recovery Program (TRRP) for people hospitalized after a traumatic injury. It includes education, symptom tracking, and referrals to mental health services. Researchers will follow 350 participants for 12 mon…

This study looks at whether training psychiatric care teams to talk about sexual health with young patients (ages 15 and up) increases those conversations. Researchers will survey 770 teens hospitalized for psychiatric disorders about their sexual health and any side effects from…

This study looks at how exercise affects the way people with PTSD learn and remember emotional information. One hundred adults with PTSD from interpersonal violence will do either moderate or light cycling after recalling a traumatic memory. Researchers will measure anxiety, hear…

This study compares different training methods for therapists who treat PTSD. It aims to find the most effective way to train therapists so they stick to the proven treatment plan. 240 therapists will be assigned to various training components, like online courses or feedback ses…