MDMA therapy trial targets PTSD and alcoholism in veterans

NCT ID NCT07118839

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether MDMA-assisted therapy can help veterans with both PTSD and alcohol use disorder. Eighty veterans will receive either a full dose of MDMA or a low-dose placebo during three therapy sessions. Researchers will measure changes in PTSD symptoms and drinking habits over about 16 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MDMA (midomafetamine hydrochloride)

What this could lead to

If successful, this could provide a new treatment option for veterans struggling with both PTSD and alcohol use disorder, potentially reducing symptoms and drinking.

What could go wrong

This is an early-phase trial with only 80 participants. The active placebo design may limit clear results, and MDMA has known risks like increased heart rate and psychological distress.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alcohol abuse post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Providence VA Medical Center, Providence, RI

    RECRUITING

    Providence, Rhode Island, 02908-4734, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • VA Connecticut Healthcare System West Haven Campus, West Haven, CT

    RECRUITING

    West Haven, Connecticut, 06516-2770, United States

    Contact Email: •••••@•••••