Brain training shows promise for PTSD in veterans

NCT ID NCT06629064

Recruiting now Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study tests whether a computer-based working memory training program can help veterans with PTSD improve their ability to unlearn fear responses. 120 veterans will be randomly assigned to either the training or a sham version. The goal is to see if the training changes brain activity and reduces fear during extinction learning, which could lead to better PTSD treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Working memory training (computer-based cognitive exercises)
What this could lead to: If it works, this training could be a new tool to help veterans with PTSD better respond to exposure therapy or even serve as a standalone treatment.
What could go wrong: This is an early-stage study with only 120 participants, so results may not apply to everyone. The training is computer-based and may not work for all PTSD symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute stress disorder post-traumatic stress disorder Stress Disorders, Traumatic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-TRAUMATIC STRESS DISORDER POST-TRAUMATIC STRESS DISORDERS PTSD STRESS DISORDERS, TRAUMATIC TRAUMA AND STRESSOR RELATED DISORDERS

Contacts and locations

Locations

VA San Diego Healthcare System, San Diego, CA
RECRUITING

San Diego, California, 92161-0002, United States

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