Could a simple nerve zap help veterans heal from brain injury and PTSD?

NCT ID NCT04437498

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a non-invasive device that stimulates the vagus nerve (a key nerve in the body) to see if it can improve memory and reduce PTSD symptoms in veterans with mild traumatic brain injury. One hundred veterans will receive either active stimulation or a sham (fake) treatment twice daily. Researchers will measure changes in PTSD symptoms, memory, brain blood flow, and stress-related inflammation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

non-invasive vagal nerve stimulation (nVNS) device

What this could lead to

If it works, this could offer a new, drug-free way to ease memory problems and PTSD symptoms in veterans with mild traumatic brain injury.

What could go wrong

This is an early-stage study with only 100 participants, so results may not apply to everyone. The treatment is compared to a sham device, and it's unclear if benefits will last long-term.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic post-traumatic stress disorder traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atlanta VA Medical and Rehab Center, Decatur, GA

    RECRUITING

    Decatur, Georgia, 30033-4004, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact