Could a 7-Day pill ease PTSD in veterans?
NCT ID NCT04452500
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a drug called CORT108297, which blocks the stress hormone cortisol, as a short-term treatment for PTSD in veterans. Forty veterans with PTSD will take either the drug or a placebo daily for one week. The goal is to see if it reduces PTSD symptoms and to check its safety for future, larger studies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CORT108297 (a drug that blocks the hormone cortisol)
What this could lead to
If it works, this could point toward a new short-term treatment to ease PTSD symptoms in veterans.
What could go wrong
This is a small, early-phase trial with only 40 participants and a 7-day treatment. It may not show clear benefits, and safety is still being established.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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San Francisco VA Medical Center, San Francisco, CA
RECRUITINGSan Francisco, California, 94121-1563, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Tuscaloosa VA Medical Center, Tuscaloosa, AL
RECRUITINGTuscaloosa, Alabama, 35404, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••