Neurotic disorder

This study tests a small ear device that gently stimulates nerves to see if it helps people with both PTSD and opioid use disorder stay on buprenorphine therapy. Twenty participants will use either the active device or a placebo for 12 weeks. Researchers will check if they keep t…

This completed study tested a program called RISE (Resiliency in Stressful Experiences) for young men ages 18-35 leaving state prisons in Florida. The program combines trauma counseling with practical help like housing and job support. Researchers measured whether participants ha…

This early-stage study is testing whether combining standard psychiatric medications (like antidepressants and anti-anxiety drugs) with individual cognitive behavioral therapy can improve symptoms and daily functioning in people with anxiety, depression, PTSD, OCD, bipolar disord…

This study tests whether using MRI to guide transcranial magnetic stimulation (TMS) works better than the usual scalp-based method for treating depression. It involves 54 participants, including those with treatment-resistant depression and others with COVID-related distress. The…

This study tested a treatment called CPT-SMART that combines PTSD therapy, smoking cessation counseling, medication, and financial incentives to help veterans quit smoking. 120 veteran smokers with PTSD were randomly assigned to either the full program or a control group. The goa…

This trial tests whether a structured family support program helps relatives of critically ill patients in intensive care units (ICUs). The program includes a specialist nurse who supports families from admission through discharge and follow-up, plus better communication between …

This study tests whether a computer-assisted tool helps mental health providers in rural VA clinics deliver cognitive behavioral therapy (CBT) more effectively for depression and anxiety. About 34 therapists and 167 veterans will take part. Therapists are randomly assigned to use…

This small study tested whether transcranial magnetic stimulation (TMS) can lower blood pressure and ease PTSD symptoms in women aged 18-44 who have both conditions. Four participants received 30 TMS sessions over 6 weeks. Researchers measured changes in 24-hour blood pressure an…

This study tests a new behavioral therapy called OPT-A for teenagers who have both substance use problems and mood or anxiety disorders. 140 teens aged 10-17 will receive either OPT-A or standard treatment. Researchers will track substance use and mental health for 18 months to s…

This study tested a blended collaborative care model that uses telemedicine to integrate mental health treatment into primary care at smaller VA clinics serving rural veterans. Researchers enrolled 318 veterans who screened positive for depression, alcohol use disorder, or PTSD. …

This study tested whether N-acetylcysteine (NAC), a widely available supplement, could help people with both alcohol use disorder and PTSD. 182 adults took either NAC or a placebo daily for 12 weeks, along with weekly therapy. Researchers measured changes in drinking habits, crav…

This study tested a collaborative care model for people with opioid use disorder and depression, anxiety, or PTSD. 567 adults received medication (buprenorphine-naloxone or naltrexone) along with therapy and support from a primary care team. The goal was to reduce opioid use and …

This study tested a program that combines small loans and group support to help people with HIV in Kenya. The goal was to improve HIV medication adherence, mental health, and family relationships. 843 people took part, and the program aimed to reduce depression, anxiety, and PTSD…

This study tested a 12-week health program for 60 older adults (65+) living in temporary container housing after the February 2023 earthquakes in Turkey. The program included personalized exercise, nutrition advice, and health counseling. Researchers measured changes in balance, …

This study tested two common treatments for depression and PTSD—talk therapy (IPT) and an antidepressant (fluoxetine)—in a large public hospital in Kenya. Over 2,100 adults participated to see if these treatments could be effectively delivered by non-specialists in primary care. …

This study followed 44 people with PTSD who had already completed a prior methylone (TSND-201) trial. Over 52 weeks, researchers checked their symptoms and safety each month. If PTSD symptoms returned, participants could receive more methylone treatment. The goal was to see if th…

This study tested whether an electronic self-report screening system (eScreening) helps VA clinics detect depression, PTSD, alcohol problems, and suicide risk more quickly and more often in newly enrolled post-9/11 veterans. Researchers compared screening rates and referral times…

This study tests a simple writing exercise for new mothers who had a stressful childbirth. In the days after giving birth, participants write about their experience for 15 minutes a day for three days. The goal is to see if this can prevent post-traumatic stress disorder (PTSD) a…

This study tested whether personalized, intensive nursing follow-up (by phone, home visits, or hospital consultations) after a suicide attempt could prevent another attempt or crisis in people with mood disorders. 380 participants were followed for one year. The goal was to see i…

This study tested whether prazosin, a drug normally used for high blood pressure, could prevent post-traumatic stress disorder (PTSD) in people who recently experienced a traumatic event like an accident or assault. Researchers gave the drug to 15 adults who showed signs of acute…

This study tested whether a single dose of hydrocortisone, given within 6 hours of a traumatic event, could prevent PTSD. 201 trauma survivors from two hospitals received either hydrocortisone or a placebo. Researchers tracked their mental health for 28 weeks to see if the drug r…

Researchers at the University of Tulsa are testing a five-session psychological treatment called Exposure, Relaxation, and Rescripting Therapy for adults who have bipolar disorder and chronic trauma nightmares. The therapy asks participants to revisit and rewrite their nightmares…

Researchers at the University of Tulsa are studying Exposure, Relaxation, and Rescripting Therapy (ERRT), a brief treatment for frequent trauma-related nightmares. The trial enrolls about 90 adults who have experienced trauma and have roughly one nightmare per week. Participants …

This study tested whether a 3-month home exercise program on an elliptical machine and 3 months of bright light therapy could improve movement, balance, and mood in adults with traumatic brain injury. Thirty-four participants (including healthy volunteers) were enrolled. The goal…

This pilot study tests whether a short, 5-session writing therapy called Written Exposure Therapy (WET) is practical and helpful for pregnant or postpartum adolescents and young adults (ages 15-24) with PTSD. The therapy involves writing about traumatic experiences with minimal t…

Researchers in Pakistan are comparing two psychological treatments, Eye Movement Desensitization and Reprocessing (EMDR) and Cognitive Behavioral Therapy (CBT), for people with post-traumatic stress disorder (PTSD) and major depression. The trial enrolls 100 adults aged 18 to 60 …

Researchers are testing MDMA-assisted therapy in military veterans who have both alcohol use disorder and post-traumatic stress disorder. The treatment combines two monthly therapy sessions with the drug MDMA, along with preparation and follow-up counseling. The study measures ch…

Researchers are comparing two 9-week group classes for veterans who have a history of mild traumatic brain injury and post-traumatic stress disorder. One class teaches mindfulness, meditation, and yoga; the other teaches how the brain works and recovers after injury. The study me…

Researchers are testing whether propranolol, a common blood pressure drug, can help people with fibromyalgia who also have post-traumatic stress disorder. Participants take propranolol and then read their own traumatic story about 75 minutes later, once a week for six weeks. The …

Researchers at Brigham and Women's Hospital are testing whether automated motivational messages or coach support can improve engagement with SilverCloud, a digital mental health intervention for depression and anxiety. The trial enrolls adults with clinically significant symptoms…

This study tested whether a type of compassion meditation could help Veterans with chronic pain who also have depression or PTSD. 142 Veterans were randomly assigned to either compassion meditation training or a health education group. The goal was to see if meditation could redu…

This study tested a new therapy called Processing of Positive Memories Technique (PPMT) for people with PTSD. Unlike standard treatments that focus on trauma, PPMT helps patients recall and describe positive memories. 70 adults with PTSD were randomly assigned to either PPMT or s…

This study tests a mobile health system (smartwatch and app) combined with a week-long cycling event to help veterans reduce stress and PTSD symptoms. Thirty-six veterans will use the system for two months and participate in the cycling challenge. The goal is to see if this appro…

This study tested whether a natural brain chemical called pregnenolone can reduce PTSD symptoms in Iraq and Afghanistan veterans. 96 veterans with PTSD took either pregnenolone or a placebo for 10 weeks and had their symptoms checked regularly. The goal was to see if the suppleme…

This study tested whether a painless brain stimulation technique called tDCS could help veterans suffering from chronic pain, PTSD, and depression. 38 veterans received tDCS sessions during an intensive outpatient program. Researchers measured changes in pain levels and mental he…

This pilot study tests whether a three-session EMDR grief protocol can reduce traumatic grief, PTSD symptoms, and emotional processing difficulties in adults who lost a loved one in the February 2023 Kahramanmaraş earthquakes. Participants are randomly assigned to receive the the…

This trial tests whether a group-based psychological treatment for insomnia, adapted for people with depression, anxiety, or PTSD, can improve sleep and reduce psychiatric symptoms. Participants receive either the adjusted CBT-i program or usual care. The study measures changes i…

This study tests whether low-cost virtual reality (VR) tools, like 360° video and a new VR Photoscan process, can help people with post-traumatic stress disorder (PTSD) engage more easily with trauma-focused therapy. Participants will receive standard therapy (TF-CBT) either alon…

This trial tests a new psychoeducation program that teaches military veterans with PTSD how sensory processing affects their stress, emotions, and daily life. Participants learn strategies to better regulate overwhelming situations, improve sleep, and engage socially. The study a…

This study tests whether a medically supervised 12-week ketogenic diet is practical for 6 adults with PTSD in Germany. The main goal is to see if people can stick to the diet and complete the study. It is not designed to measure how well the diet works for PTSD symptoms, but it m…

This trial is testing a program called TEAMSS, designed to help fifth graders with elevated anxiety transition more smoothly to middle school. The program includes reading materials, a school tour, group sessions, parent meetings, and teacher consultations. The goal is to see if …

This pilot trial tests whether pediatric primary care providers can effectively deliver a brief intervention called the Anxiety Action Plan (AxAP) to help children aged 6-17 with elevated anxiety symptoms. Providers receive training and coaching to administer the intervention, wh…

This study tested whether repeated doses of ketamine, an FDA-approved anesthetic, could speed up the effects of talk therapy (Prolonged Exposure) for PTSD in 75 veterans. Participants received either ketamine or a placebo alongside therapy. The goal was to see if ketamine could r…

This study looked at whether a web-based program called webSTAIR, which teaches skills to manage emotions and relationships, is feasible and helpful for people with PTSD who are on a waitlist for behavioral health treatment. Seventy adults from a hospital clinic in Boston took pa…

This study tests a counseling program for caregivers of children hospitalized for a traumatic injury like burns or a car accident. The goal is to reduce PTSD and depression in both the caregiver and child. 24 caregiver-child pairs will be randomly assigned to either the counselin…

This study tested whether monthly 45-minute psychological interviews over 6 months could reduce post-traumatic stress symptoms in cancer patients affected by the COVID-19 pandemic. It included 29 adults with solid tumors who had moderate to high PTSD symptoms. The goal was to see…

This trial tests whether an internet-based self-help program called Couple HOPES can reduce PTSD symptoms and improve relationship satisfaction in couples where one partner is a military member, veteran, first responder, or healthcare worker with COVID-19-related PTSD. Participan…

This trial tests whether an intensive version of Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), delivered during a hospital stay, helps children and teens aged 11–17 with PTSD after sexual abuse. Researchers compare the inpatient program to standard outpatient therapy to s…

This pilot trial tests whether adding microcurrent neurofeedback (MCN) to standard residential treatment helps adults with substance use disorder more than standard care alone. MCN uses scalp sensors to deliver barely perceptible electrical pulses tailored to each person's brain …

This pilot trial tests whether a brief group therapy called EMDR-IGTP-OTS can reduce posttraumatic stress symptoms in migrants attending an adult education center in Italy. Participants receive four structured group sessions on consecutive days and are compared with a control gro…

This study tested a group-based writing therapy for Chinese teenagers with PTSD or complex PTSD. 53 teens took part, with some receiving the therapy right away and others placed on a waiting list. The therapy involved 5 to 8 group sessions where participants wrote about their tra…

This study is testing a prescription digital therapeutic app, OTX-601, designed to deliver evidence-based PTSD treatment through a smartphone. Researchers are comparing two versions of the app—one with a higher 'dose'—against standard care (therapy and/or medication) in 40 adults…

This study looks at whether oxytocin, a natural hormone, can boost the effects of a special talk therapy for veterans who have both alcohol use disorder and PTSD. About 175 veterans will get either oxytocin or a placebo along with therapy. The goal is to see if oxytocin helps the…

This small study looked at whether firefighters could use a mild brain stimulation device (CES) at home for four weeks. The goal was to see if it's practical and if it helps with symptoms of depression, anxiety, and posttraumatic stress. Thirteen active-duty firefighters particip…

This study tests whether a medication called RE03 (dexmedetomidine), already used in intensive care, can improve sleep in people with PTSD who have trouble sleeping or nightmares. Twenty-four adults with PTSD will receive either the drug or a placebo in random order, and their sl…

This study tested whether a smartphone app that retrains attention can help people with post-traumatic stress disorder (PTSD). Over 1,300 adults with PTSD symptoms used one of four app versions for two weeks. Researchers measured changes in PTSD symptoms right after training and …

This study tests a therapy called the Unified Protocol, designed to help people with emotional disorders like anxiety and depression by improving emotional regulation. Researchers compare delivering the therapy in online group sessions versus in-person group sessions to see if bo…

This study tested whether a group therapy program for PTSD, led by people who have themselves been incarcerated, is helpful and practical. Fifty-nine adults who had completed a prison or jail sentence and had PTSD symptoms took part in a 12-session cognitive processing therapy gr…

This pilot study tested a new therapy called Psychological Cognitive Reprocessing Procedure (P-CRP) in 43 adults with trauma and grief. Unlike standard treatments, P-CRP starts by silently repeating a word tied to a negative belief while tapping the shoulders, letting the mind pr…

This study tests whether a daily nasal spray of insulin can reduce PTSD symptoms. Twenty adults with current PTSD will receive either insulin or a placebo for several weeks. Researchers will measure symptom changes using a standard PTSD scale.

This early-phase trial tests a new brain stimulation target for people with depression plus at least one other psychiatric disorder, such as anxiety, OCD, or PTSD. The treatment uses a non-invasive form of brain stimulation called accelerated intermittent theta burst stimulation …

This study tests whether a brief, telehealth-delivered therapy called Written Exposure Therapy (WET) can help autistic adults who have experienced trauma. Participants complete five weekly writing sessions and wear a Fitbit to track sleep, activity, and heart rate. The goal is to…

This study tests whether a 6-week mindfulness program (MBSR) can reduce PTSD symptoms and improve quality of life in people who have been in a road traffic accident. About 110 adults aged 18-60 with PTSD will be randomly assigned to either MBSR or standard care. Researchers will …

This pilot study tests whether a short, evidence-based therapy called Written Exposure Therapy (WET) can help reduce PTSD symptoms in adults who are in residential treatment for substance use disorders. Participants complete five guided writing sessions about their trauma. The st…

This trial tests whether a brief online group therapy called EMDR Flash can help adults who survived the 2023 Kahramanmaraş earthquakes in Türkiye. Participants receive two 60-90 minute group sessions via Zoom and are compared to a waitlist group. The study measures changes in PT…

This study tested whether adding dog-assisted therapy to usual care helps teens aged 12-18 with mental health issues like anxiety, depression, and emotional dysregulation. 70 teens in a day hospital were randomly assigned to either get dog therapy plus usual care or usual care al…

This pilot study tested a new type of brain stimulation, called accelerated intermittent theta burst stimulation (aiTBS), for people with anxiety disorders or PTSD. Fifteen participants received the non-invasive treatment targeting a novel brain area. The study measured changes i…

This study tests if group cognitive behavioral therapy (CBT) can reduce anxiety and insomnia in teens aged 12-20. About 171 participants with both conditions will receive either CBT for anxiety or CBT for insomnia. The goal is to see which approach better improves symptoms, sleep…

This study tested whether transcranial magnetic stimulation (TMS) — a non-invasive treatment that uses magnetic fields to stimulate specific brain areas — can improve daily functioning in veterans with PTSD. Researchers compared real TMS to a sham (fake) treatment in 59 veterans.…

This study tests whether adding the blood pressure medication propranolol to cognitive processing therapy (a type of talk therapy) helps people with both post-traumatic stress disorder (PTSD) and alcohol use disorder. About 48 adults aged 18 to 70 with both conditions will receiv…

This study looked at whether giving a special therapy called EMDR to people in the emergency room right after a traumatic event could help prevent post-traumatic stress disorder (PTSD). About 110 adults who were at high risk for PTSD took part. The therapy uses eye movements to h…

This study tested a shorter version of Cognitive Processing Therapy (CPT) for Veterans with PTSD. Many Veterans drop out of the standard 12-session therapy, missing the most helpful parts. The goal was to find which therapy components work best and deliver them in fewer sessions …

This study looked at whether adding a type of talk therapy called prolonged exposure therapy (PET) to standard opioid addiction treatment can help reduce PTSD symptoms. 82 adults with both opioid use disorder and PTSD took part. Some got only addiction treatment, while others als…

This study tested whether using magnetic pulses (rTMS) on the brain while people recall their traumatic memories can reduce PTSD symptoms. 39 adults with PTSD for at least 3 months received either 10Hz or 1Hz rTMS over 2 weeks. Researchers measured changes in PTSD severity using …

This study tested a type of talk therapy called Behavioral Activation (BA) in 10 U.S. veterans who have both alcohol use disorder and PTSD. BA helps people change their daily activities and thinking to reduce drinking and PTSD symptoms. The study compared BA to another therapy ca…

This study tested a device called Reacor that uses biofeedback to teach mindfulness by showing your heart rate and brain waves in real time. 188 adults with anxiety disorders were split into three groups: biofeedback alone, the medication escitalopram alone, or both together. The…

This study tested a type of group therapy called Resilience-Oriented Therapy (RoT) for adults in Rwanda who were struggling with mental health issues like trauma, depression, anxiety, or anger. 427 people took part, and the therapy was tailored to each person's main problem, such…

This study tested a 6-week mindful self-compassion program for homeless women with PTSD and substance use. The program includes meditation, group discussions, and home practices. Researchers compared the program to usual care in 202 women living in a residential drug treatment fa…

This study tested two sleep medications, trazodone and eszopiclone, in 673 veterans with PTSD-related insomnia. The goal was to see if these drugs could reduce insomnia symptoms over 12 weeks. Participants were adults aged 18-75 with military-related PTSD and insomnia. The study …

This study tested whether Eye Movement Desensitization and Reprocessing (EMDR) therapy can help adults with post-traumatic stress disorder (PTSD) in Jordan. 70 people with moderate to severe PTSD symptoms were randomly assigned to receive EMDR from a psychiatric nurse or to a wai…

This study tested whether transcranial magnetic stimulation (TMS), a noninvasive treatment that uses magnetic fields to stimulate brain regions, can improve PTSD symptoms and related brain activity. Fifty adults with partial PTSD received either active TMS or a sham procedure ove…

This study tested three ways to deliver Acceptance and Commitment Therapy (ACT) for adults aged 20-40 with mild to moderate PTSD in Pakistan. Participants were split into three groups: standard clinic therapy, clinic therapy with a supporting web app, and fully online therapy wit…

This study tested two brief, video-based therapies for women who experienced sexual assault and now struggle with PTSD and heavy drinking. One therapy focused on facing trauma memories, the other on building healthier drinking habits. The goal was to see if these short treatments…

This study tested a brief, community-based psychological program called Problem Management Plus to see if it can reduce depression, anxiety, and distress. Over 1,200 adults with mild to moderate symptoms took part. The program focuses on practical problem-solving skills in just f…

This study tested whether a short digital task could help NHS staff who kept having unwanted, intrusive memories of traumatic events from working during the COVID-19 pandemic. About 122 healthcare workers took part, using either a memory-competing computer game, a music-listening…

This study tested a program called MOSAIC Plus for pregnant women and mothers of children under 5 who have experienced intimate partner violence and have symptoms of depression or PTSD. The program pairs women with community advocates who provide support and teach skills to impro…

This study tested whether a 6-week group therapy program (cognitive behaviour therapy) could help reduce anxiety and stress in pregnant women and new mothers. 72 women from Manitoba, Canada, who were pregnant or within 12 months postpartum and had an anxiety disorder took part. T…

This study tested whether a smartphone app could help people with PTSD quit smoking and avoid starting again. Participants received counseling, stop-smoking medications, and rewards for not smoking, plus the app. The goal was to see if the app made it easier to stay smoke-free co…

This study tested a personalized treatment plan for 3 mothers and their young children (ages 4-6) who experienced domestic violence and were living in a shelter. The plan included trauma therapy (EMDR) for the parent and child, plus attachment-based therapy, in an order tailored …

This study tested whether a short, trauma-focused therapy called Narrative Exposure Therapy (NET) can help low-income urban teens aged 16–25 who have PTSD from violence and are at risk for substance use. Researchers measured changes in PTSD symptoms and alcohol use. The goal was …

This study tested a 5-week behavioral therapy for women who experienced sexual assault and use alcohol. The therapy combines writing about the trauma with skills to manage alcohol cravings. Researchers measured changes in drinking habits and PTSD symptoms. The goal is to see if e…

This study tested whether interpersonal psychotherapy (IPT) works as well as two established treatments for chronic post-traumatic stress disorder (PTSD): prolonged exposure therapy and relaxation therapy. 110 adults with chronic PTSD took part, receiving weekly sessions over 14 …

This study looked at whether a special therapy called EMDR or antidepressant medication (SSRIs) helps people with PTSD grow and recover after trauma. 130 adults with PTSD were randomly assigned to one of the two treatments. The main goal was to see which approach leads to more pe…

This completed study tested two common PTSD treatments head-to-head: EMDR therapy (a talking therapy with eye movements) and SSRI antidepressants. Sixty adults with PTSD were randomly assigned to one treatment for six weeks. Researchers measured how many people achieved symptom r…

This study looked at whether adding lofexidine to standard buprenorphine treatment can improve symptoms of both PTSD and opioid use disorder in veterans. 84 veterans on stable buprenorphine therapy were enrolled. The goal was to see if the combination reduced opioid use and PTSD …

This study looked at whether adding cannabidiol (CBD) to prolonged exposure therapy can reduce PTSD symptoms in military veterans. 136 veterans took either CBD or a placebo alongside their therapy sessions. The goal was to see if CBD helps improve treatment outcomes.

This study tested whether a guided meditation called yoga nidra is practical and helpful for people with PTSD and insomnia. Sixty adults who had experienced a stressful or traumatic event and had trouble sleeping took part. They listened to online recordings daily for 8 weeks, an…

This study tests a therapy called Interaction Guidance Therapy (IGT) for mothers with post-traumatic stress disorder (PTSD) after a traumatic pregnancy or childbirth. The therapy uses video feedback to help mothers become more sensitive to their baby's cues. Researchers will comp…

This study tested compassion-focused therapy (CFT) in 24 women with complex PTSD who struggle with harsh self-criticism. Over 12 weekly group sessions, participants learned skills to be kinder to themselves. Researchers measured changes in self-criticism, PTSD symptoms, and shame…

This pilot study tested whether a single 2-hour breathwork session could help veterans with PTSD. 36 adults took part in a group training led by a certified instructor, followed by a 30-minute talk with a psychologist. The main goal was to see if the approach was practical and ac…

This study tested a weight management program called MOVE!+UP, designed specifically for veterans with PTSD who are overweight or obese. The program adds extra support to standard PTSD care to help overcome barriers like stress and unhealthy habits. Researchers compared it to the…

This study tested whether virtual peer support groups, co-led by a mental health clinician and a trained peer specialist, could help veterans with serious mental illness (like schizophrenia or bipolar with psychosis) feel more socially connected and less distressed. Twenty-eight …

This study looked at whether mindfulness training could help veterans with PTSD who struggle with anger and aggression. 61 veterans took part. The goal was to see if learning to focus on the present moment could help them control angry feelings and reduce aggressive behavior.

This study tested whether low-intensity focused ultrasound, aimed at the amygdala (a brain area linked to emotions), could reduce symptoms of depression, anxiety, bipolar disorder, and PTSD. Twenty-nine adults received daily 10-minute sessions for three weeks. Researchers measure…

This study tested whether an adapted form of Narrative Exposure Therapy (NET) is acceptable and helpful for adults with mild learning disabilities who have experienced trauma. Thirteen participants completed the therapy, which involved talking through their life events in a struc…

This study tested a group therapy called Cognitive Processing Therapy (CPT) for incarcerated men and women with PTSD. 117 participants were either given the therapy or placed on a waitlist. The main goal was to see if the therapy reduced PTSD symptoms, with secondary goals of red…

This study tested whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help adults with PTSD from combat or terror. Thirty people who had PTSD for at least 4 years and hadn't improved with standard treatments received 60 daily sessions. Researche…

This pilot study tested a short psychological program called Problem Management Plus (PM+) in 64 refugees and asylum seekers in Switzerland. The program, developed by the World Health Organization, uses simple techniques like problem-solving and stress management to reduce psycho…

This study tested a 30-minute web-based program for parents of children with anxiety who are waiting for cognitive behavioral therapy. The program aims to reduce how much parents accommodate their child's anxiety, which can make anxiety worse. Researchers recruited 47 parents and…

This study tested a brief virtual therapy called MAPP (Mindful Adaptive Practice in Pregnancy) to help pregnant women manage COVID-19-related anxiety. 69 women participated, comparing MAPP to usual care. The goal was to see if the therapy is feasible and acceptable, not yet to pr…

This study tested whether methylone, a substance similar to MDMA, can safely reduce PTSD symptoms in adults. 79 participants with moderate to severe PTSD received either methylone or a placebo once a week for four weeks, then were followed for six more weeks. The goal was to see …

This study tested a wearable device called NightWare that uses an Apple Watch to detect when a person is having a nightmare and gently vibrates to wake them just enough to stop the nightmare without fully waking them. The trial included 270 veterans and active-duty service member…

This small study tested whether shining special LED lights on the head could help veterans with mild traumatic brain injury (TBI) and PTSD think more clearly and feel better. Eight veterans received the noninvasive light treatment, and researchers measured changes in memory, atte…

This study tested a program called EMPOWER for veterans who completed trauma-focused therapy for PTSD and saw improvement. The program includes a workbook and four therapist check-ins over 12 weeks to help veterans manage symptoms on their own. Researchers wanted to see if it cou…

This small study tested whether 8 sessions of brief exposure therapy combined with moderate exercise can reduce PTSD symptoms in adults. Twelve participants attended twice-weekly sessions for 4 weeks and completed questionnaires. The goal was to see if this treatment is acceptabl…

This study tested whether a simple technique called progressive muscle relaxation training can reduce symptoms of post-traumatic stress disorder (PTSD) in people affected by the February 6 Kahramanmaraş earthquake. 44 adults with PTSD took part. The training involves tensing and …

This study tested a new type of therapy called reminder-focused positive psychiatry (RFPP) for teenagers who have both ADHD and PTSD. The goal was to see if the therapy is acceptable and helpful for reducing symptoms. Eleven teens took part, and the study measured how well they l…

This study tested a therapy called Cognitive Behavioral Therapy for Work Success (CBTw) in 294 veterans with serious mental illness (like depression, bipolar disorder, or PTSD) who were unemployed. The goal was to help them find and keep competitive jobs, which can improve their …

This study tested a 5-week online group program called Rare Group Problem Management Plus (PM+) for parents of children with rare diseases. The program teaches stress management and problem-solving skills to help reduce anxiety, depression, and distress. Eight parents participate…

This study looked at whether a 10-week compassion meditation course is a practical and acceptable treatment for veterans with PTSD. Researchers enrolled 113 veterans across multiple U.S. sites and compared the meditation program to a standard relaxation course. The main goal was …

This study tested a personalized version of cognitive processing therapy (CF-CPT) for veterans with PTSD. 179 veterans participated to see if tailoring therapy to individual needs improves daily functioning, quality of life, and treatment completion compared to standard therapy. …

This study tested whether a probiotic called Lactobacillus rhamnosus GG can reduce inflammation and PTSD symptoms in veterans. Researchers enrolled 383 veterans with PTSD and gut issues, giving them either the probiotic or a placebo. The goal was to see if calming inflammation in…

This study looked at whether 6 months of supervised exercise training could reduce PTSD symptoms and improve physical health in older veterans with PTSD. 80 veterans took part, with one group doing exercise and another receiving health education. The goal was to see if exercise c…

This study tested a group writing therapy for Chinese teenagers with PTSD. 53 teens took part, with some getting the therapy and others on a waiting list. The goal was to see if writing about their trauma in a group setting could ease PTSD symptoms. Results suggest it may help, b…

This study tested whether tailored online writing exercises could help sexual minority women, transgender, and nonbinary people who have experienced trauma. The goal was to reduce PTSD symptoms and heavy drinking. 131 participants completed the writing program and were followed f…

This study tested whether taking part in art activities like theatre, dance, visual arts, music, or cinema can improve mental health. 541 adults with psychiatric diagnoses were randomly assigned to either an art program or a waitlist. Researchers measured changes in depression an…

This study tested whether a three-week aerobic exercise program could reduce PTSD symptoms and improve sleep in 82 adults who survived the February 2023 earthquake in Turkey. Participants were randomly assigned to either supervised exercise sessions or a control group. Researcher…

This study tested whether a simple writing therapy, done over video calls, could help prevent or reduce PTSD in women who recently experienced sexual assault. Thirty women who visited a Sexual Assault Nurse Examiner (SANE) clinic within 7 days of the assault took part. The therap…

This study tested whether adding oxytocin (a natural hormone) to standard talk therapy helps Veterans with PTSD feel better faster and stay in treatment longer. About 180 Veterans took part, receiving either oxytocin or a placebo alongside therapy sessions. The goal was to see if…

This study tested a behavioral sleep treatment in 36 veterans who have PTSD, insomnia, and sleep apnea. The goal was to see if improving sleep also improves quality of life and daily functioning. Participants attended therapy sessions and reported their sleep and well-being throu…

This study tested two online courses designed to help paramedics in Singapore manage stress, anxiety, depression, and burnout during the COVID-19 pandemic. 63 paramedics took part, completing six weekly online modules. The goal was to see which course better improved mental healt…

This study tested a new way to make nightmare therapy more effective for people with PTSD. 46 adults practiced changing their nightmares during the day (imagery rehearsal therapy). While they slept, half of them heard a sound linked to their new, positive dream ending. The idea w…

This study tested whether a single dose of the antibiotic minocycline, given before guided memory recall, could reduce the strength of intrusive memories in people with PTSD or cocaine use disorder. 138 participants took either minocycline or a placebo and then imagined a persona…

This study tested whether Eye Movement Desensitization and Reprocessing (EMDR) therapy, a proven treatment for trauma, can help people recently diagnosed with HIV. Forty participants were split into two groups: one received standard medical care plus weekly EMDR for up to 6 month…

This pilot study tested whether adding a type of brain stimulation called TMS to an intensive 2-week PTSD program could improve symptoms in veterans. Six participants received daily TMS sessions alongside their regular therapy. The study measured changes in PTSD and depression sy…

This study tested a modified version of Goal Management Training, called Trauma-Informed Goal Management Training (TI-GMT), in 33 adults with PTSD. The program teaches mindfulness and goal-setting skills over nine weekly online sessions. Researchers measured changes in PTSD sympt…

This study tested a type of talk therapy called Acceptance and Commitment Therapy (ACT) to help veterans with PTSD improve their social support and relationships. 107 veterans took part, and the therapy focused on helping them feel less isolated and more connected to family and f…

This study looked at whether adding a brief writing therapy called Written Exposure Therapy (WET) to a standard 28-day residential addiction program helps veterans with both PTSD and substance use disorders. Fifty-six veterans were randomly assigned to either standard care alone …

This study tested a new way of delivering care for people with anxiety and depression in Danish general practices. 302 adults with conditions like panic disorder, social anxiety, or PTSD took part. The model involved a team of doctors, nurses, and therapists working together, and…

This study tested a program called MOSAIC Plus for 15 pregnant women and mothers of young children who had experienced intimate partner violence and had symptoms of depression or PTSD. The program lasted 6 months and aimed to reduce those symptoms and prevent further violence. Th…

This small study tested whether adding esketamine (a nasal spray approved for depression) to prolonged exposure therapy could help people with PTSD. Four adults completed 10 daily therapy sessions over two weeks while receiving esketamine. The main goal was to see if the combinat…

This study tested two types of online therapy for anxiety and depression in 2477 adults. Participants received either a cognitive behavioral treatment or a psychodynamic treatment, delivered over 8 or 16 weeks, with or without a support forum. The goal was to see which combinatio…

This study tested whether a single session of playing Tetris after briefly recalling a traumatic childbirth memory could reduce the number of intrusive memories and PTSD symptoms in new mothers. 120 women who had given birth at least six weeks ago and reported frequent intrusive …

This completed study tested a free mobile app called Ísland that uses artificial intelligence and virtual reality to help teens aged 13–19 manage anxiety. The app combines four proven therapies, offers private journaling, video group sessions, and VR exercises to face fears safel…

This study looked at whether a type of talk therapy called prolonged exposure therapy can help reduce PTSD symptoms in people with spinal cord injuries. Thirty adults with both conditions were randomly assigned to receive the therapy or continue their usual care. The main goal wa…

This pilot study tested a behavioral program called Compensatory Cognitive Training (CCT) in 21 veterans with PTSD who still had memory and attention problems despite prior treatment. CCT teaches practical strategies to work around cognitive difficulties, like using reminders and…

This study tested an online cognitive behavioral therapy (CBT) program designed to reduce stress and prevent mental health problems in health workers caring for COVID-19 patients. 156 healthcare workers participated, receiving either the online CBT or a bibliotherapy program. The…

This study tested a personalized magnetic brain stimulation therapy called MeRT for people with PTSD. 158 adults received either real or sham treatment. The goal was to see if MeRT could safely reduce PTSD symptoms. The approach tailors the stimulation to each person's brain wave…

This study tested whether adding a social support program to standard therapy helps trauma-affected refugees with PTSD. 196 unemployed refugees received either standard treatment or standard treatment plus collaboration with municipal social services. The goal was to improve dail…

This pilot study tested whether prolonged exposure teletherapy can help adults with psychogenic nonepileptic seizures (PNES) and PTSD. Forty-four participants received either the teletherapy or standard education about PNES. The goal was to see if the therapy reduces seizure freq…

This study tested an 8-week mindfulness-based psychoeducation program in 50 adults diagnosed with anxiety disorders. Half took the program, half did not. Researchers measured changes in perceived stress, intolerance of uncertainty, and cognitive flexibility. The goal was to see i…

This study looked at whether taking estrogen pills along with a type of talk therapy called prolonged exposure (PE) can improve PTSD symptoms in women. 83 women aged 18-45 with PTSD took part. They were randomly assigned to receive either estrogen or a placebo pill with their the…

This study tested a therapy called ACT-MI for veterans struggling with moral injury—pain from events that went against their values. 74 warzone veterans took part to see if the therapy was acceptable and practical. The goal was to help them live meaningful lives, not to cure a di…

This study tested whether a mild electrical brain stimulation technique called tDCS could improve the results of trauma-focused therapy for people with PTSD. 63 adults with chronic PTSD received either real tDCS or a fake version during therapy sessions. The goal was to see if th…

This study tested a short virtual reality program called SHINE-VR for 6 adolescents aged 12-17 who had experienced sexual abuse and felt trauma-related shame. The program included three VR sessions focused on psychoeducation and sharing feelings in a virtual group. Researchers me…

This study tested a short video and a 3-week text messaging program for adults who recently experienced sexual assault. The goal was to see if these tools could help prevent or reduce posttraumatic stress disorder (PTSD) and opioid misuse. Fifty participants received the video du…

This study tested a low-dose, empowerment-based tool to help veterans with PTSD set personal goals and improve their quality of life. 44 veterans participated and were followed for 12 months. Researchers measured changes in quality of life, PTSD symptoms, and daily functioning.

This study tested an online program called ALDER that teaches older adults skills to boost positive emotions and reduce anxiety. 33 people aged 65 and older who used benzodiazepines (anti-anxiety or sleep medications) at least twice a week took part. Over 5 weeks, they learned an…

This study tested whether a program called Equine Assisted Learning (EAL) can reduce trauma symptoms in public safety personnel like police, firefighters, and paramedics. 40 participants from Saskatchewan took part in 16 sessions of unmounted activities with horses, guided by men…

This small study tested whether MDMA, combined with talk therapy, could help veterans with PTSD and their intimate partners. Sixteen couples took part. The goal was to see if this approach could reduce PTSD symptoms and improve relationship satisfaction. Results are not yet avail…

This study tested a new, short, and intensive therapy called HANDS-ON for 12 teens (ages 10-18) with anxiety or obsessive-compulsive disorder (OCD) who hadn't improved with standard therapy. The treatment involved personalized exposure exercises done at home and school, with help…

This study tested whether virtual reality (VR) sessions can help reduce anxiety and depression in people aged 12 to 25 who do not want to take medication. Forty participants completed five weekly VR sessions focused on relaxation, coping skills, and healthy habits. Researchers me…

This study tested a drug called methylone in 62 adults with severe PTSD. Participants took methylone capsules once a week for 3 to 4 weeks. Researchers measured changes in PTSD and depression symptoms to see if the drug is safe and helpful.

This study tested a single-session program for children ages 7 to 17 with anxiety and their parents. The program teaches kids how to manage anxious thoughts and feelings, and shows parents how to support them. Researchers wanted to see if this quick help could reduce anxiety symp…

This study tested a program called the Pregnant Moms' Empowerment Program (PMEP) for pregnant women who had experienced intimate partner violence in the past year. The goal was to see if the program could improve mothers' mental health, reduce the chance of further violence, and …

This study tested a therapy called Impact of Killing (IOK) for veterans with PTSD caused by moral injury—distress from killing or being responsible for a death in war. One hundred veterans received either IOK or a standard PTSD therapy over 10 sessions. The goal was to see if IOK…

This study tested whether a website called Heartsight could help close family members of cardiac arrest patients feel less uncertain, anxious, and burdened. Fifty-three family members were given access to the website or usual care. The goal was to see if the website was easy to u…

This study looked at whether veterans with PTSD would find a wearable device called Apollo acceptable and easy to use. The device delivers gentle vibrations at different times of day. 63 veterans used it for about 6 weeks, and researchers checked how credible and satisfying they …

This study tested a 10-week group therapy program called START-PTSD for 45 veterans with PTSD who had declined standard trauma-focused treatment. The therapy helps veterans identify and gradually reduce 'safety aids'—behaviors like avoiding certain places or using mental distract…

This study tested a 4.5-hour somatic psychoeducational program for healthcare providers to see if it could improve their mental and physical health. Thirty-one bedside nurses participated, completing surveys and saliva tests before, one week after, and one month after the program…

This study tested whether a single therapy (Transdiagnostic Behavior Therapy) works as well as separate, disorder-specific therapies for veterans with PTSD, major depression, or panic disorder. 304 veterans participated, and researchers measured symptoms before, during, and after…

This study looked at whether a non-invasive brain training method called neurofeedback can help veterans who have had a mild traumatic brain injury and still suffer from chronic headaches, trouble sleeping, and attention problems. 87 veterans were randomly assigned to receive neu…

This study tested a workshop called STEP-Home for 221 post-9/11 Veterans who had trouble reintegrating into civilian life. The workshop taught skills like emotional control, problem solving, and attention to improve daily function and reduce anger. It was designed as a non-stigma…

This study tested whether adding a stellate ganglion block (a numbing injection in the neck) to cognitive processing therapy (a type of talk therapy) helps reduce PTSD and chronic pain more than therapy alone. Sixty adults with PTSD took part. The goal was to see if the combinati…

This study tested whether adding the sleep medication eszopiclone (Lunesta) to brief behavioral therapy improves sleep quality and CPAP use in veterans with PTSD and complex insomnia. Fifty-three veterans who had trouble sticking with CPAP therapy for sleep apnea took part. The g…

This study tested a new way to treat post-traumatic stress disorder (PTSD) in veterans and active-duty service members. Instead of relying on talk therapy, which can be stressful and has high dropout rates, researchers used a device called transcranial magnetic stimulation (TMS) …

This study tested a one-day life skills workshop for veterans with mild traumatic brain injury, chronic pain, and mental health conditions like PTSD and depression. The workshop taught coping strategies to reduce distress and improve reintegration into civilian life. 176 veterans…

This study tested whether using virtual reality (VR) exposure therapy could prevent anxiety, depression, and PTSD in people recovering from a lung transplant in the ICU. 62 adults on the lung transplant waiting list participated. They used a VR headset to gradually get used to st…

This study tested whether taking part in art activities (like painting, music, or dance) can improve mental well-being. 382 people with mental health issues such as anxiety, depression, or emotional disorders were randomly assigned to either an art program or a waitlist. The stud…

This study looked at whether the drug tolcapone can help veterans with mild traumatic brain injury improve memory and self-regulation. Fifty-five veterans underwent brain scans and cognitive tests while taking either tolcapone or a placebo. The goal was to see if the drug changes…

This study tested whether a mobile app called Messy Memories could help people who had been in the intensive care unit (ICU) deal with distressing memories. The app guides users to record and process a difficult memory on their own. Researchers wanted to see if people would actua…

This study tested whether adding cognitive behavioral therapy (CBT) to a gradual benzodiazepine taper helps patients with anxiety who also take prescription opioids reduce their benzodiazepine use. 42 primary care patients were randomly assigned to receive either CBT or a health …

This study tested a group version of a therapy program called the Unified Protocol for teens with emotional disorders like anxiety and depression. Thirty-one adolescents took part in 16 weekly group sessions at a public mental health center in Spain, along with three parent sessi…

This study tested whether a daily 3-minute laughter practice (called a Laughie Prescription) could improve well-being, happiness, and post-traumatic stress in 50 nursing students who lived through the earthquake in Türkiye. Participants laughed for one minute in a group and then …

This study tested whether Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) can reduce PTSD and depression symptoms in children aged 8 to 19 when delivered in schools. It also tested a strategy to help school clinicians adopt and stick with the therapy. The trial involved 292 …

This study tested a mobile app called BounceBack Now, designed to help people manage trauma-related mental health issues like PTSD, depression, and anxiety. Researchers worked with 29 adults in primary care, including many from underserved groups, to see if the app was easy to us…

This study tested whether Written Exposure Therapy, a treatment where people write about their traumatic experiences, can work when delivered virtually in a group setting. The participants were 29 military and police personnel with PTSD. The goal was to see if this approach is ac…

This study tested a new program called Adjunctive Family-Cognitive Behavioral Therapy (AF-CBT) for veterans with anxiety disorders. It involved 48 veterans and their family members to see if adding family support to standard therapy was acceptable and helpful. The main goal was t…

This pilot study tested the Safe and Sound Protocol (SSP), a device that plays filtered music through an app to stimulate the vagus nerve, in 45 therapy clients with PTSD and anxiety. Participants used the SSP alongside their regular therapy and completed questionnaires about the…

This study tested a 16-week parenting program called KEEP for foster and kinship parents. The goal was to reduce depression, anxiety, PTSD, and behavior problems in foster youth aged 4 to 21. Researchers focused on underserved and rural communities in Oregon. The program teaches …

This study tested whether a type of talk therapy called Cognitive Processing Therapy (CPT) can help adults who experienced the 2023 earthquakes in Turkey. Thirty-six participants with PTSD symptoms were randomly assigned to receive CPT or usual care. The goal was to see if CPT re…

This study tested a 10-session art therapy program for adults with trauma-related symptoms who have difficulty with traditional talk therapy. 38 participants made artwork to process memories and emotions. Researchers measured changes in emotional expression, self-esteem, and resi…

This study looked at whether teaching military members to train service dogs can improve symptoms of PTSD, anxiety, depression, and concussion. 156 participants spent one hour twice a week working with professional dog trainers. Researchers measured changes in stress, mood, sleep…

This study tested whether a racecar-simulation program combined with psychological skills training could help veterans with PTSD improve their ability to handle stress and emotions. One veteran completed the program, which included techniques like self-talk, goal-setting, and bio…

Researchers at the University of California, San Francisco are studying how the brain processes rewards in people with early-onset schizophrenia, major depressive disorder, post-traumatic stress disorder, or gambling disorder, compared with healthy volunteers. Participants comple…

This study is a small survey of 10 adults exploring how nutrition, mental health, and faith-based practices relate to recovery from trauma or PTSD. Researchers want to understand what helps people overcome life challenges after stressful events. The results will be used to design…

This study used MRI and PET scans to examine the glutamate system in people with major depression, PTSD, or bipolar disorder. Researchers aimed to understand how a specific glutamate receptor (mGluR5) relates to these conditions. 180 participants aged 18-70 completed cognitive te…

This study looks at whether post-traumatic stress disorder (PTSD) in surgeons and anesthesiologists is linked to higher rates of complications in the patients they operate on. Researchers will screen surgical staff for PTSD using questionnaires and then track the recovery of thei…

This study followed survivors of the 2015 Paris terrorist attacks for up to 6 years, using brain scans to see how trauma affects the brain's ability to control unwanted memories. Researchers compared 216 survivors with people who were not exposed to the attacks. The goal was to u…

This completed study looked at 168 adults with a history of trauma to see if PTSD harms blood vessel function, which could raise heart disease risk. Participants completed behavioral tasks measuring fear and attention, and had their blood vessel health checked. The goal is to und…

This study investigates whether the hormone estradiol influences PTSD symptoms and brain activity related to fear and stress in women. Researchers will give some participants an estradiol patch and others a placebo before MRI scans that measure brain responses to threatening cues…

This pilot study uses functional MRI to examine brain activity in trauma-exposed veterans with obsessive-compulsive personality traits, known as overcontrol. Overcontrol can strain relationships and increase suicide risk. The study aims to test whether the brain scanning methods …

This study tested whether a role model-based ethics course could reduce moral injury and stress in 101 second-year medical students in Taiwan. Students chose between a standard version with stories and handouts, or an enhanced version with extra writing and guest speakers. Resear…

This study looked at 6 children with past PTSD to see if changes in attention and memory could predict a relapse. Researchers used computer tasks and standard tests to measure brain function. The goal is to find early warning signs so families can get help sooner.

This study looks at 65 veterans with PTSD who use cannabis frequently. Researchers want to see if reducing cannabis use improves their daily functioning, mental health, and quality of life. No treatment or drug is given—participants simply report their cannabis use and well-being…

This study follows couples who gave birth in either a midwifery-led birth unit or a standard obstetric unit in France. Researchers want to see if the type of care affects parents' mental health, especially post-traumatic stress, and the child's development up to two years later. …

This study tested a coaching program for doctors to improve communication with Black and Latinx families during hospital rounds. The program taught doctors to be more respectful, collaborative, and trauma-aware. Researchers measured whether families felt more trust and satisfacti…

This study tested a program called Multi-Family Healing Spaces for families affected by the Rwandan genocide. 319 family members aged 12 and older from five districts took part. The program aimed to improve family communication, resilience, and mental health. Results will show if…

This study tested whether a single 15-minute session of Butterfly Tapping, a self-administered EMDR technique, could change brain activity in 46 young adults with PTSD. Participants either did the tapping or sat still while their brain waves were recorded. The tapping group showe…

This study examines how often patients and their relatives develop post-traumatic stress disorder (PTSD) after a sudden cardiac arrest. Researchers interviewed 45 people (20 survivors and 20 relatives) within a week of the event and again at 3 months using standard questionnaires…

This study tested whether offering tai chi classes online is a practical way to help veterans with PTSD and chronic pain. Researchers worked with 42 veterans to see if they would attend sessions and find the program satisfactory. The goal was to gather information needed to desig…

This study tested a 10-item questionnaire called DEPITAC, designed for nurses to screen road traffic accident patients for post-traumatic stress disorder (PTSD) while they are still in the surgical unit. Researchers enrolled 274 hospitalized accident victims to see if the simple …

This study looked at how people with PTSD pay attention to their surroundings. Researchers used a change blindness test to see if patients are quicker to notice changes, especially emotional ones. 80 adults with PTSD and healthy controls participated. The goal was to understand t…

This study tested whether a training program called Modeling to Learn (MTL) helps clinic staff improve how many veterans start and finish evidence-based treatments for PTSD, depression, and opioid use disorder. The program uses computer simulations to let staff try out changes to…

This study looked at why Interpersonal Psychotherapy (IPT) helps people with PTSD. Unlike most PTSD therapies, IPT does not involve re-living traumatic memories. Instead, it focuses on improving relationships and emotional awareness. Researchers measured emotional awareness in 29…

This completed Phase 3 substudy looked at whether MDMA-assisted psychotherapy can change how stress-related genes work in people with PTSD. Researchers collected saliva samples from 45 participants before and after treatment to measure changes in gene activity. The goal was to se…

This small study tested whether a gentle brain stimulation technique called HD-tDCS could improve the effects of cognitive behavioral therapy (CBT) for people with depression, anxiety, or PTSD. Twenty participants received either real or fake stimulation daily for five weeks whil…

This study looked at whether adding specialty palliative care early on to standard intensive care can improve the experience for critically ill older adults (age 60+) and their families. Over 1,000 patients and their family members took part. The goal was to see if this approach …

This study in Cameroon tested whether training healthcare workers improves how they screen and manage post-traumatic stress disorder (PTSD) in road traffic injury patients. Researchers trained staff at one hospital and measured changes in knowledge and screening rates over six mo…

This study looked at a telemedicine program called TOP that helps rural veterans with PTSD get care without traveling far. Over 500 veterans took part. The goal was to see which method of rolling out the program worked better to reach more patients and improve PTSD symptoms.

This study looked at whether a 5-session class teaching cognitive behavioral therapy (CBT) skills can increase a brain pattern linked to resilience against PTSD. It involved 30 public safety personnel (like police or firefighters) who were already in a larger study. Researchers u…

This study looked at whether watching short science videos can change how adults with anxiety think about psychological therapy. 262 participants watched 30 minutes of educational videos and filled out surveys about their beliefs and expectations. The goal was to understand if sc…

This study looks at how a cardiac arrest affects brain function, including memory, thinking, and emotions. Researchers will follow 48 survivors for one year, using cognitive tests and brain scans (fMRI) to track changes. Their results will be compared to a healthy control group t…

This study monitored the sleep of 48 veterans with trauma-related nightmares using in-home devices. Researchers aimed to understand how nightmares affect sleep and how they change with cognitive-behavioral therapy. The goal is to improve personalized care for veterans suffering f…

This study looked at how psychological trauma affects memory and brain function in teenagers with post-traumatic stress disorder (PTSD). Researchers used MRI scans to compare brain activity in 19 adolescents with PTSD and healthy teens. The goal was to understand the brain areas …

This study looked at how mindfulness-based cognitive therapy (MBCT) changes brain activity in 61 adults with PTSD. Participants received either MBCT or a mind-body comparison therapy, and researchers used fMRI scans to measure brain connectivity before and after treatment. The go…

This study looked at whether treating insomnia can reduce the risk of heart disease in people with PTSD. Researchers measured blood pressure, blood vessel health, and other heart risk factors in 140 adults aged 40-59. The goal was to see if improving sleep could also improve hear…

This study tested a new Dutch questionnaire designed to measure how people with PTSD think about their trauma—specifically, whether they blame themselves, feel a loss of control, or see the trauma as affecting everything in their lives. Researchers enrolled 530 participants, incl…

This study looked at whether people with sensory modulation problems (like being overly sensitive to sounds or touch) are more likely to develop PTSD after a traumatic event. Researchers showed 248 healthy adults a stressful film and tracked their memories, pain sensitivity, and …

This study tested a psychoeducational program called Finding Solid Ground for 30 adults with dissociative disorders caused by childhood trauma. Participants received 3 months of inpatient treatment and continued the program as outpatients. Researchers measured changes in trauma s…

This study looked at how negative emotions and stress influence alcohol use in 81 women veterans, including those with PTSD. Researchers measured cravings, heart rate, and drinking patterns, and also examined how these effects change across the menstrual cycle. The goal was to be…

This study tested whether a brain wave measurement called mismatch negativity (MMN) can help match veterans with mental illness to the most effective cognitive training program. 100 veterans with conditions like schizophrenia, PTSD, or mood disorders participated. The goal was to…

This completed study surveyed 3,100 adults in Slovakia to find out how many people have mental disorders like depression, anxiety, PTSD, or addiction. Researchers used a standard interview tool to measure current and lifetime rates, and looked at who gets help and who doesn't. Th…

This study looked at 200 emergency nurses in Turkey to understand how often they face stressful and traumatic events at work and how those events affect them emotionally. The nurses answered a questionnaire about their experiences over the past six months. The goal was to identif…

This study tested a program called IPS-MA, which helps people with mood or anxiety disorders find and keep jobs or return to school. 326 adults who were unable to work within three months took part. The goal was to see if this support, added to their usual treatment, helped them …

This study tested a mobile health tool called CAARE to help children under 12 and their caregivers cope with emotional and behavioral challenges after a traumatic injury. Researchers measured changes in distress, PTSD symptoms, depression, and quality of life in 54 participants. …

This study tested whether giving PTSD therapy several times a week (massed) helps veterans stay in treatment better than once-a-week sessions. Thirty veterans with PTSD were randomly assigned to either massed or weekly therapy. Researchers measured how many completed treatment an…

This study tested a program called SLAC that helps Veterans who drink heavily and have mental health issues like PTSD or depression get connected to alcohol care. 140 Veterans from VA primary care took part. The goal was to see if the program is practical and liked by Veterans an…

This Stanford study explores how brain circuits relate to anxiety and depression. 167 participants with recent symptoms (no diagnosis needed) undergo brain scans and cognitive tests. Some also receive a 12-week course of pramipexole medication or rTMS therapy. The goal is to unde…

This study tested whether keeping a hospital diary during a child's stay in the pediatric intensive care unit (PICU) could improve mental health outcomes for families. Over 400 families participated across four PICUs in Rio de Janeiro. Researchers measured anxiety, depression, PT…

This study looks at 125 patients who were in the ICU, on a breathing machine and sedated for at least 48 hours. Researchers want to see how many have trouble with thinking or memory four months after leaving the hospital. Patients will talk to a psychologist before leaving the IC…

This study aimed to find factors that can predict whether someone will develop post-traumatic stress disorder (PTSD) after a traumatic event like a serious injury or violence. Researchers followed 460 adults who came to the emergency room within a month of trauma and were at mode…

This study looked at whether inflammation in the body is linked to suicidal thoughts and behaviors in teenagers. Researchers took blood samples and surveyed 225 teens aged 12-18, including those with recent suicidal behavior, those at risk for depression, and healthy controls. No…

This study looked at whether keeping a diary during intensive care can lower the risk of post-traumatic stress disorder (PTSD) in people who survived a sudden cardiac arrest and in their family members. About 173 patients and their relatives took part. Researchers measured PTSD s…

This study looked at the psychological impact of the COVID-19 pandemic on healthcare workers in intensive care units. Over 700 doctors, nurses, and aides completed questionnaires about post-traumatic stress, anxiety, depression, and burnout. The goal was to measure how common the…

This study looked at how people with post-traumatic stress disorder (PTSD) predict their emotional reactions to future events. Researchers compared 97 participants with and without PTSD to see if those with PTSD tend to expect more intense negative emotions than they actually exp…

This study looked at how the COVID-19 pandemic impacted the mental health of 501 nursing home workers in Occitanie, France. Researchers measured rates of post-traumatic stress disorder (PTSD), depression, and burnout using standard questionnaires. The goal was to understand how c…

This study looked at the specific symptoms of complex post-traumatic stress disorder (PTSD) compared to regular PTSD. Researchers used questionnaires to measure dissociation, emotional control, and trauma in 300 adults. The goal was to better understand and identify complex PTSD,…

This study looked at whether a special planning tool, called a POST form, helps older adults (65+) get the medical care they prefer at the end of life. Researchers worked with 389 people, including those with dementia, to see if their treatment matched their wishes. The goal was …

This study tested whether brain wave patterns during sleep can detect PTSD and measure how severe it is. Researchers studied 26 veterans with PTSD using EEG recordings. The goal is to create an objective test that goes beyond questionnaires and doctor assessments.

This study tested whether a smartphone app could help veterans with serious mental illnesses like schizophrenia and bipolar disorder track their own symptoms. 87 veterans used the app to monitor their activity, sleep, and social interactions. The goal was to see if this data coul…

This study created and tested a mobile app called VetEd for student veterans dealing with mental health issues like depression, PTSD, or anxiety. The goal was to help them manage academics, mental health, and find resources. Researchers worked with 13 veterans to see if the app w…

This study looked at whether the timing of mild brain stimulation (tDCS) can help people with PTSD better learn that a once-feared situation is now safe. 62 adults with PTSD received either real or fake stimulation during different phases of a fear-learning task. The goal was to …

This study followed 38 adults who survived severe breathing failure from the 2009 H1N1 flu. Researchers compared those who needed a machine to oxygenate their blood (ECMO) with those who did not. They measured lung function, quality of life, and mental health at least 9 months af…

This study looked at how a single dose of dronabinol (a synthetic cannabinoid) affects fear-related brain activity in people with PTSD, trauma-exposed individuals without PTSD, and healthy controls. Using brain scans, researchers measured how the drug influences fear extinction c…

This study looked at whether a single 20-minute aerobic exercise session could help women with PTSD symptoms regulate emotions and improve cognitive control. Sixty-seven women were randomly assigned to either exercise or silent sitting. Researchers measured brain activity and sel…

This study followed 14 people who called a crisis hotline after terror attacks in Paris, London, Barcelona, and Strasbourg. Researchers asked them to rate how their symptoms changed over time. The goal was to understand what kind of help they needed.

This study looked at whether using very low nicotine cigarettes along with nicotine-containing e-cigarettes can reduce harmful chemical exposure in smokers with mental health conditions. 88 participants were assigned to different combinations of cigarettes and e-cigarettes. The m…

This early-stage trial tested the safety and drug levels of methylone in 40 healthy volunteers aged 25 to 55. Participants received a single oral dose of methylone or a placebo. The study measured how the drug moves through the body and checked for side effects. This is a first s…

This study looked at whether a simple questionnaire called the City Birth Trauma Scale (CityBiTS) can accurately identify post-traumatic stress disorder (PTSD) related to childbirth. Researchers recruited 67 women who had given birth, had them fill out the questionnaire, and then…