Could a party drug ease PTSD?

NCT ID NCT06215261

Completed Symptom relief Sponsor: Transcend Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a drug called methylone in 62 adults with severe PTSD. Participants took methylone capsules once a week for 3 to 4 weeks. Researchers measured changes in PTSD and depression symptoms to see if the drug is safe and helpful.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: methylone
What this could lead to: If it works, this could point toward a new treatment option for people with PTSD.
What could go wrong: This is a small, early-phase trial with only 62 participants. It may not work for everyone, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-TRAUMATIC STRESS DISORDER

Contacts and locations

Locations

Accel Research

Maitland, Florida, 32751, United States
CNS Healthcare

Orlando, Florida, 32801, United States
Clerkenwell Health

London, United Kingdom
Monarch Mental Health Group

Melbourne, Victoria, Australia
Numinus

Draper, Utah, 84020, United States
Ramsay Clinic Albert Road

Melbourne, Victoria, 3004, Australia
Redbird Research LLC

Las Vegas, Nevada, 89119, United States
Seattle NTC

Bellevue, Washington, 98004, United States
Segal Trials

Lauderhill, Florida, 33319, United States
Sunstone Medical

Rockville, Maryland, 20850, United States
Swinburne University of Technology

Hawthorn, Victoria, 3122, Australia
Uptown Clinical Research

Chicago, Illinois, 60640, United States

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