Could a brain steroid help veterans heal from PTSD?
NCT ID NCT03799562
First seen Jan 16, 2026 · Last updated Jun 08, 2026 · Updated 21 times
Summary
This study tested whether a natural substance called pregnenolone can reduce PTSD symptoms in 96 Iraq/Afghanistan-era veterans. Over 10 weeks, participants took either pregnenolone or a placebo and had regular check-ins and assessments. The goal was to see if this supplement could ease the mental and physical effects of PTSD.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Durham VA Medical Center, Durham, NC
Durham, North Carolina, 27705-3875, United States
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