Could a brain steroid help veterans with PTSD?
NCT ID NCT03799562
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a natural brain chemical called pregnenolone can reduce PTSD symptoms in Iraq and Afghanistan veterans. 96 veterans with PTSD took either pregnenolone or a placebo for 10 weeks and had their symptoms checked regularly. The goal was to see if the supplement could ease PTSD and related issues like pain.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Durham VA Medical Center, Durham, NC
Durham, North Carolina, 27705-3875, United States
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