New study aims to bring depression and PTSD treatment to millions in kenya

NCT ID NCT03466346

Completed Disease control Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two common treatments for depression and PTSD—talk therapy (IPT) and an antidepressant (fluoxetine)—in a large public hospital in Kenya. Over 2,100 adults participated to see if these treatments could be effectively delivered by non-specialists in primary care. The goal was to find affordable, practical ways to help people with mental health issues in low-resource settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Fluoxetine (antidepressant medication) and Interpersonal Psychotherapy (talk therapy)
What this could lead to: If successful, this could show that combining simple treatments like therapy and medication works well for depression and PTSD in places with few mental health specialists.
What could go wrong: This study is already completed, so results are known. However, the treatments may not work for everyone, and access to ongoing care could still be a challenge in real-world settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

depressive disorder injury major depressive disorder post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION, UNIPOLAR POSTTRAUMATIC STRESS DISORDER TRAUMA

Contacts and locations

Locations

Jaramogi Oginga Odinga Teaching and Referral Hospital (JOOTRH)

Kisumu, Kenya
Kisumu County Hospital

Kisumu, Kenya
Lumumba Health Center

Kisumu, Kenya

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