MDMA therapy could rewire stress genes in PTSD patients

NCT ID NCT06189027

First seen May 05, 2026 · Last updated May 12, 2026 · Updated 4 times

Summary

This study looked at whether MDMA-assisted psychotherapy can change how certain stress-related genes work in people with PTSD. Researchers collected saliva samples from 45 participants before and after treatment to measure changes in gene activity. The goal was to see if these genetic changes are linked to improvements in PTSD symptoms. This was an add-on to a larger Phase 3 trial testing MDMA-assisted therapy versus placebo.

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Contacts and locations

Locations

  • Univeristy of Southern California

    Los Angeles, California, 90089, United States

Conditions

Explore the condition pages connected to this study.