New combo approach targets insomnia in veterans with PTSD
NCT ID NCT03937713
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 41 times
Summary
This study tested whether adding the sleep medication eszopiclone (Lunesta) to brief behavioral therapy improves sleep quality and CPAP use in veterans with PTSD and complex insomnia. Fifty-three veterans who had trouble sticking with CPAP therapy for sleep apnea took part. The goal was to see if the combination helps them sleep better and manage PTSD symptoms.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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VA Western New York Healthcare System, Buffalo, NY
Buffalo, New York, 14215-1129, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
eszopiclone (Lunesta)
What this could lead to
If successful, this could point toward a better way to improve sleep and CPAP use in veterans with PTSD and insomnia.
What could go wrong
This is a small, completed Phase 4 trial with only 53 participants, so results may not apply broadly. The drug eszopiclone can cause side effects like drowsiness or dizziness.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.