Estrogen plus talk therapy shows promise for PTSD in women
NCT ID NCT04192266
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether taking estrogen pills along with a type of talk therapy called prolonged exposure (PE) can improve PTSD symptoms in women. 83 women aged 18-45 with PTSD took part. They were randomly assigned to receive either estrogen or a placebo pill with their therapy sessions over six weeks. The goal was to see if estrogen helps the brain respond better to therapy and reduces PTSD symptoms.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The University of Texas Health Science Center at Houston (UTHealth Houston)
Houston, Texas, 77054, United States
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University of Pennsylvania Perelman School of Medicine
Philadelphia, Pennsylvania, 19104, United States
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