New drug combo shows promise for veterans battling PTSD and opioid addiction
NCT ID NCT04360681
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether adding lofexidine to standard buprenorphine treatment can improve symptoms of both PTSD and opioid use disorder in veterans. 84 veterans on stable buprenorphine therapy were enrolled. The goal was to see if the combination reduced opioid use and PTSD symptoms better than buprenorphine alone.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Michael E. DeBakey Veterans Affairs Medical Center
Houston, Texas, 77030, United States
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South Texas Veterans Health Care System
San Antonio, Texas, 78229, United States