Could a common blood pressure pill stop PTSD before it starts?

NCT ID NCT03045016

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether prazosin, a drug normally used for high blood pressure, could prevent post-traumatic stress disorder (PTSD) in people who recently experienced a traumatic event like an accident or assault. Researchers gave the drug to 15 adults who showed signs of acute stress disorder within a week of the trauma. The goal was to see if blocking certain stress-related brain signals could stop PTSD from developing.

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Conditions

The condition(s) this trial relates to.

acute stress disorder injury Stress Disorders, Traumatic, Acute post-traumatic stress disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Groupement Hospitalier Edouard Herriot - Emergency Psychiatry Department

    Lyon, 69003, France