Can sound waves soothe pain and cravings? new trial investigates

NCT ID NCT06297200

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether low-intensity focused ultrasound (LIFU) — a noninvasive device that sends sound waves to the brain — can help people with chronic back pain, opioid cravings, and anxiety. Researchers will enroll 25 adults and measure safety, mood, heart rate, and other changes. The goal is to see if this gentle brain stimulation could ease multiple symptoms at once.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Low-Intensity Focused Ultrasound (LIFU) device

What this could lead to

If it works, this could point toward a noninvasive brain stimulation option to help manage chronic pain, opioid cravings, and anxiety together.

What could go wrong

This is a very early, small study (25 people) focused on safety and basic effects, so results may not apply broadly. The treatment is still experimental and may not provide lasting relief.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Chronic Pain chronic pain syndrome opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fralin Biomedical Research Institute at VTC

    RECRUITING

    Roanoke, Virginia, 24016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact