Sleep drug shows promise for dual diagnosis of alcoholism and PTSD

NCT ID NCT06679062

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 study tests whether the sleep medication suvorexant can reduce insomnia in 76 adults aged 21–65 who have both alcohol use disorder and posttraumatic stress disorder. Participants take either suvorexant or a placebo for 14 days while trying to stop drinking. The study measures changes in sleep quality and alcohol cravings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

suvorexant

What this could lead to

If it works, this could point toward a new way to treat insomnia in people with both alcohol use disorder and PTSD, potentially helping them reduce drinking.

What could go wrong

This is a small, early-phase trial with only 76 people and a short 14-day treatment period. Results may not apply to everyone, and suvorexant may not work better than placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alcohol abuse insomnia post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas Health Science Center - Houston

    RECRUITING

    Houston, Texas, 77054, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • University of California - Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact