Should you switch PTSD therapies? new study aims to find out

NCT ID NCT06957067

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two strategies for veterans struggling with Cognitive Processing Therapy (CPT) for PTSD: using CPT skills to work through challenges, or switching to a different therapy called Present Centered Therapy. The goal is to see which approach reduces dropout and improves PTSD symptoms, depression, and daily functioning. Researchers will track 280 veterans to find the best way to keep people engaged in treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cognitive Processing Therapy (CPT) skills and Present Centered Therapy (PCT)

What this could lead to

If successful, this could help therapists know when to switch PTSD treatments to keep veterans in therapy and improve their symptoms.

What could go wrong

This is a behavioral study, not a drug trial, so results may be subtle. It is still recruiting and outcomes depend on individual responses to therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • New Orleans VA Medical Center

    RECRUITING

    New Orleans, Louisiana, 70119, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ralph H. Johnson VA Health Care System (Charleston VA)

    RECRUITING

    Charleston, South Carolina, 29401, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Houston Healthcare System

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Phoenix Health Care System

    RECRUITING

    Phoenix, Arizona, 85012, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••