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Brain zaps guided by MRI aim to quiet PTSD symptoms

NCT ID NCT06449326

Recruiting now Symptom relief Sponsor: University of New Mexico Source: ClinicalTrials.gov ↗

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive brain stimulation technique called intermittent theta burst stimulation (iTBS) can reduce chronic PTSD symptoms in veterans. The stimulation is guided by functional MRI scans to target a specific brain region. Half of the 64 participants receive real stimulation, while the other half receive a sham (placebo) version, to see if the treatment truly helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Intermittent theta burst stimulation (iTBS) delivered via transcranial magnetic stimulation
What this could lead to
If successful, this could offer a non-drug, targeted brain stimulation treatment for chronic PTSD symptoms in veterans.
What could go wrong
This is a small, early-stage trial (64 participants) with a sham control, so results may not generalize. The treatment is experimental and may not provide lasting relief.

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTTRAUMATIC STRESS DISORDER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • New Mexico VA Health Care System

    RECRUITING

    Albuquerque, New Mexico, 87108, United States

    Contact Phone: •••-•••-••••

  • UNM Center for Psychiatric Research

    RECRUITING

    Albuquerque, New Mexico, 87106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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