Can a single IV dose rewire traumatic memories in PTSD?
NCT ID NCT07079761
First seen Nov 05, 2025 · Last updated May 26, 2026 · Updated 26 times
Summary
This study looks at whether a single intravenous dose of allopregnanolone, a natural brain chemical, can help people with PTSD better process traumatic memories. About 96 adults with chronic PTSD will receive either the drug or a placebo and then complete memory tasks. The goal is to see if the drug helps the brain 'extinguish' fear responses or block the re-consolidation of traumatic memories.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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