Zapping the brain to forget fear: new study targets PTSD prevention

NCT ID NCT05560113

Recruiting now Knowledge-focused Sponsor: Emory University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study explores whether a non-invasive brain stimulation technique called cTBS can disrupt the consolidation of fear memories shortly after a traumatic event. Researchers will use functional MRI and skin conductance responses to measure changes in brain connections and fear reactions. The goal is to see if this approach could reduce the risk of developing PTSD in people who have experienced trauma.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: continuous theta burst stimulation (cTBS)
What this could lead to: If successful, this could point toward a new way to prevent PTSD by weakening traumatic memories shortly after they form.
What could go wrong: This is an early proof-of-principle study with only 66 participants. It tests a lab-based fear response, not real trauma, and may not translate to clinical benefit.

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Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-TRAUMATIC STRESS DISORDER

Contacts and locations

Locations

Emory Rehabilitation Hospital
RECRUITING

Atlanta, Georgia, 30322, United States
Emory University Hospital
RECRUITING

Atlanta, Georgia, 30322, United States

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