Could a blood pressure pill ease PTSD?
NCT ID NCT07499440
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2 trial is testing whether HB-1, a tablet combining two blood pressure medications (telmisartan and verapamil), can safely reduce PTSD symptoms. About 200 adults aged 18-65 with PTSD will receive either HB-1 or a placebo daily for 12 weeks. The main goal is to see if HB-1 improves clinician-rated PTSD symptoms compared to placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
HB-1 (a combination of telmisartan and verapamil in a single tablet)
What this could lead to
If successful, HB-1 could offer a new oral treatment option to reduce PTSD symptoms, potentially improving daily functioning for people with this condition.
What could go wrong
This is a Phase 2 trial with 200 participants, so results are still early. The drug may not prove more effective than placebo, and side effects from the blood pressure medications (telmisartan/verapamil) are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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East Sydney Doctors
RECRUITINGDarlinghurst, New South Wales, 2010, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Innovate Clinical Research
RECRUITINGWaitara, New South Wales, 2077, Australia
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mackay Hospital and Health Service
NOT_YET_RECRUITINGMackay, Queensland, 4740, Australia
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Monash Alfred Psychiatry Research Centre
NOT_YET_RECRUITINGMelbourne, Victoria, 3004, Australia
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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NeuroCentrix
NOT_YET_RECRUITINGCarlton, Victoria, 3053, Australia
Contact Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Novatrials
RECRUITINGCharlestown, New South Wales, 2290, Australia
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Paratus Clinical Research Brisbane
NOT_YET_RECRUITINGHerston, Queensland, 4006, Australia
Contact Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Paratus Clinical Research Canberra
RECRUITINGBruce, Australian Capital Territory, 2617, Australia
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Paratus Clinical Research Melbourne
RECRUITINGNorthcote, Victoria, 3070, Australia
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Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Peninsula Therapeutic and Research Group
RECRUITINGFrankston, Victoria, 3199, Australia
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ramsay Clinic Albert Road
RECRUITINGMelbourne, Victoria, 3004, Australia
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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South Australian Health and Medical Research Institute
RECRUITINGAdelaide, South Australia, 5000, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Email: •••••@•••••
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University of the Sunshine Coast Clinical Trials, Morayfield
NOT_YET_RECRUITINGMorayfield, Queensland, 4506, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of the Sunshine Coast Clinical Trials, Sippy Downs
NOT_YET_RECRUITINGSippy Downs, Queensland, 4556, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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WSLHD Mental Health Services, Westmead Hospital
NOT_YET_RECRUITINGWestmead, New South Wales, 2145, Australia
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••