Antidepressant may ease pain and PTSD after trauma
NCT ID NCT06046859
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving fluoxetine (Prozac) immediately after a serious injury can prevent depression, PTSD, and reduce pain and opioid use. About 200 adults with fractures or other bodily trauma will receive either fluoxetine or a placebo during their hospital stay. The goal is to improve mental and physical recovery without changing standard pain treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Florida
RECRUITINGGainesville, Florida, 32608, United States
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