New HOPE therapy aims to tackle opioid addiction and PTSD together

NCT ID NCT06641115

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a therapy called HOPE for people who have both opioid use disorder and PTSD. Participants must already be on medication for opioid use disorder (like Suboxone or methadone). Over 10-12 weeks, they will attend therapy sessions and complete surveys to see if their opioid use and PTSD symptoms improve.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HOPE therapy (behavioral therapy)

What this could lead to

If it works, this could provide an effective integrated therapy for people struggling with both opioid addiction and PTSD, potentially improving recovery outcomes.

What could go wrong

This is a small early-stage study with only 76 participants, so results may not apply to everyone. The therapy is intensive (10-12 weeks) and may not work for all individuals.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

opiate dependence post-traumatic stress disorder Psychological Well-Being substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical University of South Carolina

    RECRUITING

    Charleston, South Carolina, 29403, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••