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Could a vaccine help us understand PTSD? new study investigates

NCT ID NCT06630884

Recruiting now Knowledge-focused Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether short-term changes in the immune system can alter how people process information and experience fear. Researchers will give some participants a typhoid vaccine (which temporarily activates the immune system) and others a placebo. By measuring physical responses like skin sweating and heart rate, they hope to better understand the link between inflammation and PTSD. The study involves 288 trauma-exposed adults, some with PTSD and some without.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Inflammation post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POSTTRAUMATIC STRESS DISORDER (PTSD)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • San Francisco VA Health Care System

    RECRUITING

    San Francisco, California, 94121, United States