Sound waves to soothe PTSD? new trial targets brain circuit in healthcare workers

NCT ID NCT07164105

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tests whether low-intensity focused ultrasound (LIFU) can calm overactive brain areas linked to PTSD in frontline healthcare workers. Sixty-six participants will receive either real or fake ultrasound to the brain's cingulate cortex. Researchers will measure changes in brain scans, symptoms, sleep, and heart rate to see if the treatment helps.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Laureate Institute for Brain Research

    RECRUITING

    Tulsa, Oklahoma, 74136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

low-intensity focused ultrasound (LIFU)

What this could lead to

If it works, this could point toward a non-invasive brain stimulation treatment for PTSD symptoms.

What could go wrong

This is a small, early-phase study with only 66 participants and a single session of treatment. Results may not apply to all PTSD patients, and the effect may be temporary or no better than sham.

Conditions

The condition(s) this trial relates to.

post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.