Exercise may rewire fear memories in PTSD patients
NCT ID NCT06127342
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looks at how exercise affects the way people with PTSD learn and remember emotional information. One hundred adults with PTSD from interpersonal violence will do either moderate or light cycling after recalling a traumatic memory. Researchers will measure anxiety, heart rate, and brain activity using MRI to see if exercise changes how the brain processes fear.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Moderate or low intensity stationary cycling
What this could lead to
If it works, this could point toward a way to boost the effectiveness of PTSD treatments by adding exercise.
What could go wrong
This is an early, small study focused on understanding brain processes, not testing a treatment. Results may not lead to a direct therapy or apply to everyone with PTSD.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Kentucky
RECRUITINGLexington, Kentucky, 40506, United States
Contact Email: •••••@•••••
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University of Texas
RECRUITINGAustin, Texas, 78712, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••