Wrist device aims to zap PTSD nightmares and save hearts

NCT ID NCT06419959

Recruiting now Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests a prescription wrist device called NightWare that detects when a veteran with PTSD is having a nightmare and gently disrupts it without waking them. Researchers want to see if better sleep from fewer nightmares can also improve blood vessel and heart health. 125 veterans with PTSD and poor sleep will be enrolled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NightWare (a wrist-wearable device that uses a proprietary algorithm to detect and disrupt nightmares without waking the user)
What this could lead to: If it works, this could offer a new, non-drug way to ease PTSD nightmares and potentially lower heart disease risk in veterans.
What could go wrong: This is a relatively small, early-stage study (125 people) testing a device, not a drug. The sham comparator group uses a disabled app, so placebo effects are possible. Success is not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AUTONOMIC DYSFUNCTION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

acute stress disorder autonomic nervous system disorder cardiovascular disorder Inflammation nervous system disorder post-traumatic stress disorder primary dysautonomia psychiatric disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTONOMIC DYSFUNCTION CARDIOVASCULAR DISEASES ENDOTHELIAL DYSFUNCTION NIGHTMARE POST TRAUMATIC STRESS DISORDER (PTSD) VASCULAR STIFFNESS VETERAN

Contacts and locations

Locations

Rocky Mountain Regional VA Medical Center, Aurora, CO
RECRUITING

Aurora, Colorado, 80045-7211, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.