Brain training game tested for anxiety, depression, and PTSD

NCT ID NCT06273527

Recruiting now Symptom relief Sponsor: University of California, San Diego Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a computer program called COGENT, designed to improve thinking skills like memory and attention in people with anxiety, depression, or PTSD. 128 adults will be randomly assigned to either the COGENT training or a sham program. Researchers will compare changes in cognitive performance and brain activity before and after the training.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: computer-based cognitive training program (COGENT)
What this could lead to: If it works, this could point toward a non-drug way to improve thinking and reduce repetitive negative thoughts in people with anxiety, depression, or PTSD.
What could go wrong: This is an early-stage study with only 128 participants, and the sham group may also show some improvement. The training is computer-based, so real-world benefits may be limited.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression depressive disorder post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY DISORDERS DEPRESSION POST-TRAUMATIC STRESS DISORDER

Contacts and locations

Locations

UC San Diego
RECRUITING

San Diego, California, 92037, United States

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