Nerve block injection may improve sleep for PTSD sufferers

NCT ID NCT07667309

Recruiting now Knowledge-focused Sponsor: The University of Texas Health Science Center at San Antonio Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at how a stellate ganglion block injection affects sleep in U.S. service members and veterans with PTSD who are already receiving talk therapy. About 40 participants will wear an EEG headband for three nights before and three nights after the injection to measure brain activity during sleep. They will also fill out questionnaires about their sleep quality. The goal is to see if the injection can improve sleep, which is often disrupted in PTSD.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: stellate ganglion block injection
What this could lead to: If successful, this could show that the injection improves sleep quality for people with PTSD, pointing toward a better understanding of how to treat sleep problems in this condition.
What could go wrong: This is a small, early observational study with only 40 participants, so results may not apply to everyone. The injection is already used for other conditions, but its effect on sleep is not yet proven.

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Conditions

The condition(s) this trial relates to.

combat disorder post-traumatic stress disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST TRAUMATIC STRESS DISORDER (PTSD)

Contacts and locations

Locations

Carl R. Darnall Army Medical Center at Fort Hood
RECRUITING

Killeen, Texas, 76544, United States
University of Texas Health Science Center at San Antonio
RECRUITING

San Antonio, Texas, 78229, United States

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