Could trauma history sabotage epilepsy surgery? a new study investigates

NCT ID NCT07718542

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This study asks whether post-traumatic stress disorder (PTSD) influences how well epilepsy surgery works. Researchers will follow 42 adults with drug-resistant focal epilepsy for two years after surgery, comparing seizure freedom and quality of life between those with and without PTSD. Participants complete questionnaires on trauma, anxiety, depression, and social factors before and after the operation. The goal is to see if psychological and social factors should be considered when predicting surgical success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If PTSD is found to affect surgical outcomes, it could lead to better pre-surgery mental health screening and personalized support to improve seizure control and quality of life.
What could go wrong
This is a small, single-center observational study with only 42 participants, so results may not apply to everyone. It looks at associations, not cause and effect.

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Conditions

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