Assistance Publique Hopitaux De Marseille

This study is testing whether a special breathing mask that provides gentle air pressure (called NIV/CPAP) works better than a standard oxygen mask for people who are struggling to breathe after a drowning incident. Researchers will compare these two approaches in 210 patients ac…

This study is testing if adding a patient's own processed fat tissue (containing healing cells) to a standard surgical procedure can help prevent urethral narrowing from recurring. It will involve 20 men with a history of this condition to see if the new approach is safe and more…

This study is testing whether a personalized, non-invasive brain stimulation treatment can reduce seizure frequency in people with drug-resistant epilepsy. 60 participants aged 9+ will receive either real or sham stimulation for 10 days in a crossover design. Researchers will mea…

This study is testing whether video consultations with geriatric and pharmacy specialists can improve care for cancer patients aged 75 and older who live far from major hospitals. It aims to see if this remote support helps reduce unexpected trips back to the hospital and better …

This study is testing if using two specific measurements of a patient's breathing effort can help doctors decide the best time to safely remove a life support machine called ECMO. The goal is to help patients with severe lung failure (ARDS) breathe on their own sooner and reduce …

This study is testing if a new type of ultrasound scan can help doctors decide when it's safe to remove a patient's breathing tube. Researchers will use special heart and lung ultrasound on 110 adults in intensive care who are trying to breathe without machine help. The goal is t…

This study aims to find the better antibiotic for preventing infections at the surgical wound site. It will compare two drugs, linezolid and vancomycin, in over 1,100 patients who are allergic to standard antibiotics or at risk for a specific hard-to-treat bacteria. The goal is t…

This study compares two approaches to physical activity for people recovering from a stroke. Researchers want to see if a structured exercise program at a dedicated facility works better than a self-directed home program. The study will measure daily steps, walking ability, balan…

This study is testing if a special hypnosis session before surgery can help reduce anxiety in children when they receive anesthesia. It involves 60 children aged 5 to 12 who are having planned surgery. Researchers will compare anxiety levels in kids who receive standard care vers…

This study is testing a new device called the Schelin catheter to deliver local anesthesia for a prostate treatment called Rezum. The goal is to see if this method reduces pain, allows the procedure to be done without general anesthesia, and helps patients recover faster. Researc…

This study aims to understand how modern melanoma treatments might affect fertility in young men and women. Researchers will track 80 participants aged 18-45, measuring ovarian reserve and sperm quality before treatment, right after, and one year later. The goal is to gather info…

This study aims to understand how being born moderately premature affects how a baby's brain processes speech sounds. Researchers will track 160 infants—some born premature, some full-term—using brain wave measurements (EEG) as they listen to syllables. The goal is to identify ea…

This study aims to understand if tiny organisms called archaea play a role in causing cavities. Researchers will collect saliva samples from 200 dental patients to check for the presence and amount of these organisms. The goal is to gather new knowledge about what causes tooth de…

This study is testing a non-invasive sensor that measures oxygen levels in the kidneys during lung transplant surgery. Researchers want to see if low oxygen readings during the operation can predict which patients will develop kidney failure in the days after surgery. The goal is…

This study aims to understand if specific immune proteins (autoantibodies) are linked to liver damage in people with anorexia nervosa. Researchers will compare blood samples from 250 people, including those with anorexia and liver issues, those with anorexia without liver issues,…

This study is creating a registry to track 200 infants with a rare, severe genetic epilepsy called KCNQ2-related epileptic encephalopathy. Researchers will follow these children long-term to better understand how their seizures, brain activity, and development progress over time.…

This study aims to find biological markers that can predict which sepsis patients will get much worse and develop septic shock. Researchers will compare blood samples from 25 male patients who have sepsis after major digestive cancer surgery. They are looking for differences betw…

This study aims to learn more about glioblastoma, a serious brain tumor, by observing 100 newly diagnosed adults. Researchers will measure specific proteins in the blood and tumor tissue to see how they relate to MRI brain scan features and change during standard treatment. The g…

This study aims to understand if certain personality traits make it easier or harder for people to learn a new way of speaking after their voice box is removed. It will involve 40 adults in France who have had this surgery and tried speech therapy. Researchers will compare person…

This study is testing a new 3D photography method to measure facial symmetry in people who have had facial reconstruction surgery. Researchers want to see if this objective measurement matches what surgeons and patients think about the results. The goal is to better understand wh…

This study aims to understand how the brain changes and adapts in various neurological conditions and during normal aging. Researchers will use advanced, high-powered MRI scans to look at brain structure, function, and energy use in 700 participants, including people with disease…

This study aims to find out if a specific substance in the blood (called EV-TF) can help predict which patients with severe lung failure (ARDS) will develop a dangerous lung clot (pulmonary embolism). Researchers will enroll 170 critically ill patients in France, take a blood sam…