Melanoma therapy may impact fertility – new study investigates

NCT ID NCT05429138

Recruiting now Knowledge-focused Sponsor: Assistance Publique Hopitaux De Marseille Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tracks fertility markers in 80 melanoma patients (women aged 18-37, men aged 18-45) before, during, and after adjuvant therapy with anti-PD-1 or targeted treatments. Researchers measure hormone levels in women and sperm quality in men to see how these change over time. The goal is to better understand the effects of modern melanoma treatments on reproductive health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors understand how melanoma treatments impact fertility, guiding future family planning advice for patients.
What could go wrong: This is an observational study, not a treatment trial. It only measures changes and does not test any new therapy or intervention.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MELANOMA

Contacts and locations

Locations

AP-HM
RECRUITING

Marseille, France
APHP- Ambroise Paré
RECRUITING

Paris, France
APHP-Cochin
RECRUITING

Paris, France
APHP-Saint Louis
RECRUITING

Paris, France
CHRU de Nîmes
RECRUITING

Nîmes, France
CHU Montpellier
RECRUITING

Montpellier, France
CHU NICE L'archet
RECRUITING

Nice, France
CHU de Bordeaux
RECRUITING

Bordeaux, France
CHU de Nantes
RECRUITING

Nantes, France
Hôpital Saint-Joseph
RECRUITING

Marseille, France
Institut Gustave Roussy
RECRUITING

Villejuif, France
Oncôpole de Toulouse
RECRUITING

Toulouse, France

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