Scientists investigate whether hidden microbes in your mouth cause tooth decay

NCT ID NCT06787261

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether archaea, a type of microbe, are involved in tooth decay. Researchers will collect saliva and cavity tissue samples from 200 adults to check for the presence and amount of archaea. The goal is to better understand what causes cavities and possibly find new ways to prevent or treat them.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If this study finds a link between archaea and cavities, it could point toward new ways to prevent or treat tooth decay by targeting these microbes.
What could go wrong
This is an early observational study, not a treatment trial. It only looks for a connection, so it may not lead to any practical changes in dental care.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asssistance Publique Hopitaux de Marseille

    RECRUITING

    Marseille, 13354, France

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