DENTAL CARIES

This study tests whether a silver liquid (silver diamine fluoride) is better than standard fluoride varnish at reducing cavity-causing bacteria in children aged 3 to 8 with tooth decay. Each child will receive both treatments on different sides of their mouth. The researchers wil…

This study follows 480 older adults living in subsidized housing to see which treatment works better long-term for stopping tooth decay: a silver diamine fluoride liquid painted on teeth or a standard filling plus fluoride varnish. Participants are aged 62 and older and will be c…

This study tests two cavity treatment methods—selective removal and stepwise removal—in 666 children and teens aged 8 to 19 with deep cavities. The goal is to see which approach better keeps the tooth alive and healthy for at least one year, avoiding the need for a root canal. Pa…

This study aims to see if simple, minimally invasive treatments can stop cavities from getting worse in children aged 6 to 12. About 2,500 kids with active tooth decay will receive special sealants and fillings, then be checked every 3 months for 2 years. The goal is to control d…

This study compares a new bioactive filling material to a standard one for treating cavities in back teeth. 34 adults will each receive two fillings, one of each type, and their performance will be checked over a year. The goal is to see if the new material lasts longer and looks…

This study tests whether a cream called MI Paste Plus can reduce harmful bacteria and prevent white spots on teeth in people wearing braces. White spots are early signs of tooth decay that can appear around brackets. The trial will include 200 people aged 5 to 45 who are starting…

This study compares two methods of hardening a tooth-colored filling material in children's baby teeth. One method uses a fast 5-second light, the other a standard longer light. The goal is to see if the fast method works just as well and is as safe. About 70 children with caviti…

This early study tests a new type of dental implant designed to feel and move more like a natural tooth. Six adults who need a single tooth pulled will get the implant right away. Researchers will check if the implant bonds with the jawbone and if it can restore normal tooth move…

This study tests whether a 3D intraoral scan (a camera that takes pictures inside your mouth) can detect dental plaque and cavities as accurately as current methods like dye and X-rays. About 50 adults aged 18 to 70 will get both the new scan and the standard checks so researcher…

This study compares different digital tools—like X-rays, AI analysis, and special cameras—against standard visual exams to see which finds cavities most accurately. About 100 adults with tooth decay will take part. The goal is to help dentists catch cavities earlier and choose th…

This study is testing whether a 12-month program for mothers can help prevent tooth decay and unhealthy weight gain in their young children. The program provides health education and helps mothers build supportive social networks. Researchers will follow 460 mother-child pairs in…

This study tests whether a liquid called PILP is safe to use when treating cavities in adults. 30 adults with at least one cavity will get either PILP or a placebo before a filling. Researchers will check tooth health, pain, and gum condition over six months to see if PILP is a s…

This study compares two modern ways to make dental fillings: 3D printing and CAD-CAM. Twelve adults with two damaged teeth will get one type of filling on each tooth. Researchers will check how well the fillings look, function, and affect gum health over two years. The goal is to…

This study looks at how placing a special type of crown (Hall crown) on decayed baby molars changes a child's bite. Researchers will use digital scans to measure tooth movements right after the crown is placed, and again at two weeks and one month. The goal is to understand how t…

This study looks at whether training doctors and changing electronic health records can encourage older adults (55+) on Medicaid to visit the dentist. About 929 people from 12 clinics will take part. The goal is to see if these changes lead to more dental visits and better oral h…

This study looks at whether archaea, a type of microbe, are involved in tooth decay. Researchers will collect saliva from 200 adults with cavities to check for these organisms. The goal is to better understand cavity causes and improve future prevention or treatment.

This study looks at two types of crowns used to fix deep cavities in children's back baby teeth: stainless steel (silver) and zirconia (white). Researchers will check how each crown affects gum health, plaque buildup, wear on the opposite tooth, and how happy parents are with the…