DENTAL CARIES

This early study tests a new type of tooth implant that uses leftover tissue from the tooth's root to help it fuse with the jawbone. About 6 adults needing a single tooth pulled will get the implant right away. Researchers will check if the implant stays stable, moves like a natu…

This study tests two ways to treat deep cavities in children and teens (ages 8-19) without removing all the decay at once. The goal is to keep the tooth alive and healthy, avoiding root canals or extractions. About 666 participants will be followed for 1 to 3 years to see which m…

This study looks at whether gentle, non-drilling treatments can stop cavities from getting worse in 2,500 Brazilian children aged 6 to 12. Kids with active tooth decay will get minimally invasive care and be checked every three months for up to two years. The goal is to control c…

This study compares a new bioactive filling material to a standard one for treating cavities in back teeth. 34 adults will each receive two fillings, one of each type, and their performance will be checked over a year. The goal is to see if the new material lasts longer and looks…

This study tests whether a silver liquid (silver diamine fluoride) is better than standard fluoride varnish at reducing cavity-causing bacteria in children aged 3 to 8 with tooth decay. Each child will receive both treatments on different sides of their mouth. The researchers wil…

This study follows 480 older adults living in subsidized housing to see which treatment works better long-term for stopping tooth decay: a silver diamine fluoride liquid painted on teeth or a standard filling plus fluoride varnish. Participants are aged 62 and older and will be c…

This study tests whether a cream called MI Paste Plus can reduce harmful bacteria and prevent white spots on teeth in people wearing braces. White spots are early signs of tooth decay that can appear around brackets. The trial will include 200 people aged 5 to 45 who are starting…

This study compares two methods of hardening a tooth-colored filling material in children's baby teeth. One method uses a fast 5-second light, the other a standard longer light. The goal is to see if the fast method works just as well and is as safe. About 70 children with caviti…

This study compares different digital tools—like AI, special cameras, and X-rays—to see how well they find cavities compared to standard visual checks. About 100 adults with tooth decay will take part. The goal is to find the most accurate way to catch cavities early, so dentists…

This study tests whether a 3D intraoral scan (a camera that takes pictures inside your mouth) can detect dental plaque and cavities as accurately as current methods. Researchers will compare the scan's results to standard plaque dye and X-rays. The study involves 50 adults aged 1…

This study tests whether a 12-month program that teaches Bangladeshi mothers about child health and oral health, and helps them build social networks, can reduce cavities and unhealthy weight gain in their young children. About 460 mothers and their children (ages 1 to 4) will ta…

This study tests whether a liquid called PILP is safe to use when treating cavities in adults. 30 adults with at least one cavity will get either PILP or a placebo before a filling. Researchers will check tooth health, pain, and gum condition over six months to see if PILP is a s…

This study compares two modern ways to make dental fillings: 3D printing and CAD-CAM. About 12 adults with two damaged teeth will get one type of filling on each tooth. Researchers will check how well the fillings look, work, and affect gum health over 2 years. The goal is to see…

This study looks at whether archaea, a type of microbe, are involved in causing cavities. Researchers will collect saliva samples from 200 adults to check for these organisms and see how they relate to cavity risk. The goal is to better understand cavity formation and improve fut…

This study watches 60 children who get Hall crowns on decayed baby molars. Researchers use digital scans to measure how the crown changes the bite and tooth positions right after placement, at two weeks, and at one month. The goal is to understand the bite adjustments, not to tes…

This study looks at whether training medical staff and updating electronic health records can encourage older adults (55+) on Medicaid to visit the dentist more often. About 929 participants from 12 clinics will be split into two groups: one gets enhanced support and education, t…

This study looks at two types of crowns used to fix deep cavities in children's back baby teeth: stainless steel (silver) and zirconia (white). Researchers will check how each crown affects gum health, plaque buildup, wear on the opposite tooth, and how happy parents are with the…