DENTAL CARIES
Clinical trials for DENTAL CARIES explained in plain language.
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Metal-Free crowns challenge gold standard for Kids' cavities
Disease control CompletedThis study tested whether new tooth-colored BIOFLX crowns work as well as the standard metal (stainless steel) crowns for fixing cavities in children's back baby teeth. 36 children each received both types of crowns on different teeth. Researchers checked how well the crowns stay…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: satish vishwanathaiah • Aim: Disease control
Last updated May 17, 2026 05:44 UTC
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Toothpaste showdown: can TheraBreath repair early cavities?
Disease control CompletedThis study tested whether TheraBreath toothpaste can help repair early tooth decay (cavities) better than a placebo or a standard toothpaste. Thirty-one adults wore a special dental device with enamel samples to measure how much fluoride the toothpaste delivered and how well it h…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Church & Dwight Company, Inc. • Aim: Disease control
Last updated May 17, 2026 05:44 UTC
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New study tests if special pastes can stop Aligner-Related tooth spots
Disease control CompletedThis study looked at 40 people wearing clear aligners to see if special remineralizing agents (CPP-ACP, nano-hydroxyapatite, or fluoride varnish) could prevent white spots that often form around the small attachments on teeth. Participants used one of these products or regular fl…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Bezmialem Vakif University • Aim: Disease control
Last updated May 17, 2026 05:35 UTC
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New study reveals best way to fix early cavities without drilling
Disease control CompletedThis study tested two treatments for early tooth decay (white spots) in 30 teenagers aged 12 to 18. Each participant received both a resin infiltration and a microabrasion treatment on different teeth to see which worked better. The goal was to improve the look of the spots and s…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Can Tho University of Medicine and Pharmacy • Aim: Disease control
Last updated May 17, 2026 05:33 UTC
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Toothpaste showdown: baking soda formula may help heal cavities
Disease control CompletedThis study tested whether a toothpaste containing fluoride and baking soda can repair early signs of tooth decay better than regular fluoride toothpaste or a toothpaste without fluoride. 31 healthy adults wore a dental device with pieces of tooth enamel for 9 days, brushing with …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Church & Dwight Company, Inc. • Aim: Disease control
Last updated May 17, 2026 05:33 UTC
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No-Drill cavity treatments work as well as fillings in kids, study finds
Disease control CompletedThis study tested three cavity treatments in 60 children aged 4 to 8. Each child got a different treatment on three teeth: a no-drill metal cap (Hall technique), a liquid that stops decay (silver diamine fluoride), or a standard filling. The goal was to see which worked best over…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: TC Erciyes University • Aim: Disease control
Last updated May 17, 2026 05:33 UTC
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New cement could save teeth from decay
Disease control CompletedThis study tested a new dental cement called ALBO-MPCA in 20 adults with tooth decay. The cement was placed directly on the tooth nerve to help it heal and form a protective layer. The goal was to see if it is safe and effective at repairing teeth without causing pain or other pr…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Albos d.o.o. Beograd • Aim: Disease control
Last updated May 17, 2026 05:32 UTC
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New study pits two filling methods against each other for better dental care
Disease control CompletedThis study looked at two ways to fix cavities in back teeth using tooth-colored materials. 90 adults with decay got either a direct filling (placed right in the mouth) or an indirect one (made in a lab and then cemented in). The goal was to see which type holds up better over tim…
Matched conditions: DENTAL CARIES
Sponsor: Recep Tayyip Erdogan University • Aim: Disease control
Last updated May 17, 2026 05:32 UTC
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Toothpaste showdown: which paste best repairs early cavities?
Disease control CompletedThis study tested three toothpastes to see how well they repair early tooth decay. Thirty adults wore a special mouth device with tooth enamel samples for one week per toothpaste. The goal was to measure how much the enamel hardened and how much fluoride it absorbed.
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Church & Dwight Company, Inc. • Aim: Disease control
Last updated May 17, 2026 05:30 UTC
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No-drill cavity treatment tested in 104 kids
Disease control CompletedThis study tested a liquid called silver diamine fluoride (SDF) that is painted onto cavities to stop them from getting worse. 104 children aged 1.5 to 8 years with cavities in baby teeth were treated with SDF every six months, with or without extra fluoride varnish every three m…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Beaty Dent • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Ancient chewing stick takes on the toothbrush in Kids' plaque battle!
Disease control CompletedThis study tested whether a 45°-cut miswak (a natural chewing stick) removes dental plaque from children's teeth as effectively as a regular toothbrush. 82 healthy kids aged 6 to 14 took part, and researchers measured plaque levels and asked which tool they preferred. The goal is…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: King Abdulaziz University • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New study tests if bioactive fillings save more teeth from decay
Disease control CompletedThis study looked at 50 adults aged 18-40 with deep cavities in their back teeth. Dentists removed only the decayed part and filled the tooth with either a bioactive or a standard non-bioactive material. The goal was to see which filling kept the tooth healthy and pain-free longe…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Light-Activated tooth treatment shows promise for Kids' cavities
Disease control CompletedThis study looked at 40 children aged 4-9 with cavities in their baby molars. After removing the decay, dentists applied a liquid called silver diamine fluoride (SDF) to stop remaining cavity germs. Half the kids also got a blue LED light shined on the tooth for 20 seconds. The g…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Çanakkale Onsekiz Mart University • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New study tests best way to stop cavities in Kids' teeth
Disease control CompletedThis study tested three treatments for early, non-cavity tooth decay in children aged 4 to 9 years. The treatments were a resin sealant, a fluoride varnish, and both combined. Over 12 months, researchers checked if the decay stopped or got worse. The goal was to find the best way…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Sacide Duman • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New cement may save Kids' teeth from extraction
Disease control CompletedThis study looked at two ways to treat deep cavities in baby molars that have caused irreversible pulpitis (nerve damage). One method uses a special cement (Biodentine) to cap the nerve, while the other removes the nerve entirely and fills the root with a paste (Metapex). The goa…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Mohamed Ahmed Hamdi Abo El Yamin • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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New toothpaste shows promise in reversing early tooth decay
Disease control CompletedThis study tested a new toothpaste with fluoride to see if it could help reverse the very early stages of cavities. 47 adults wore a device with tooth enamel samples in their mouth and used the toothpaste for 2 weeks. Researchers measured how much the enamel hardened, which indic…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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New approach aims to stop tooth decay from returning after Kids' dental surgery
Disease control CompletedThis study looked at whether offering families extra help from a pediatrician and social worker after a child's dental surgery under anesthesia can improve follow-up care. 89 children with severe tooth decay participated. The goal was to see if this support leads to fewer missed …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Helsinki University Central Hospital • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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3D scanner could replace the dental probe for Kids' checkups
Diagnosis CompletedThis study tested whether a 3D intraoral scanner can find cavities, tooth wear, and fluorosis in children's baby teeth as well as a traditional visual exam. 36 children aged 3-12 had their teeth cleaned, examined visually, and then scanned. The goal was to see if the scanner is a…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Indiana University • Aim: Diagnosis
Last updated May 15, 2026 11:55 UTC
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New Light-Based tools could catch cavities before they start
Diagnosis CompletedThis study tested four methods to find early-stage cavities in children's back teeth. Fifty-one kids aged 6 to 14 had their teeth checked using visual inspection, a laser pen, and two light-based devices. The goal was to see which method works best for catching decay early, so de…
Matched conditions: DENTAL CARIES
Sponsor: Neslihan Atmaca • Aim: Diagnosis
Last updated May 11, 2026 20:40 UTC
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Cash for cavity prevention: study tests if money motivates toothbrushing
Prevention CompletedThis study tested whether offering small financial rewards to parents helps them brush their young children's teeth more often. 244 families with children in Early Head Start programs took part. The goal was to see if this approach could prevent cavities by improving toothbrushin…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: University of California, San Francisco • Aim: Prevention
Last updated May 17, 2026 05:43 UTC
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New tooth sealant technique may keep cavities away longer
Prevention CompletedThis study looked at whether using a special glass powder spray before putting on a tooth sealant helps prevent cavities and keeps the sealant on teeth longer. Researchers tested this on 96 young adults aged 17-22. The goal is to find a better way to protect back teeth from decay…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Cairo University • Aim: Prevention
Last updated May 17, 2026 05:35 UTC
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Video teaching for dental sealants: just as good as the real thing?
Prevention CompletedThis study tested whether dental interns can learn to place pit and fissure sealants (a coating that prevents cavities) just as well from a video as from a live demonstration. Fifty children aged 7-9 each had two molars treated by different interns trained either by video or in p…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Mansoura University • Aim: Prevention
Last updated May 17, 2026 05:35 UTC
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Toothpaste showdown: fluoride vs. probiotics in Kids' cavity fight
Prevention CompletedThis study looked at whether fluoride or probiotic toothpaste can prevent cavities in 508 children aged 4-5 years. Kids brushed twice daily for 12 months with their assigned toothpaste. Researchers also surveyed kids' oral hygiene and diet to find what increases cavity risk. The …
Matched conditions: DENTAL CARIES
Phase: PHASE4 • Sponsor: The Affiliated Hospital of Qingdao University • Aim: Prevention
Last updated May 15, 2026 11:54 UTC
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New fluoride treatment may shield cancer Patients' teeth from radiation damage
Prevention CompletedThis early-phase study tested whether a professional fluoride treatment (silver diamine fluoride) can prevent tooth decay in 56 head and neck cancer patients receiving radiation therapy. Researchers applied the fluoride and checked for cavities, gum health, and quality of life. T…
Matched conditions: DENTAL CARIES
Phase: EARLY_PHASE1 • Sponsor: Texas A & M University Baylor College Of Dentistry • Aim: Prevention
Last updated May 05, 2026 11:53 UTC
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New crowns for Kids' teeth: do they hold up?
Symptom relief CompletedThis study looked at how well BioFlx crowns work for fixing cavities in children's baby molars. Twenty-eight healthy kids aged 6 to 9 got these crowns, and researchers checked their condition and satisfaction over 24 months. The goal was to see if the crowns perform well and keep…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: King Abdulaziz University • Aim: Symptom relief
Last updated May 17, 2026 05:44 UTC
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3-Second dental fillings: a game changer for cavity repair?
Symptom relief CompletedThis study tested a new dental filling material that hardens in just 3 seconds using a special light. Researchers wanted to see if it reduces tooth pain after filling and how well the fillings hold up over time. 39 adults with cavities or old fillings that needed replacement took…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Ivoclar Vivadent AG • Aim: Symptom relief
Last updated May 13, 2026 16:01 UTC
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Fluoride showdown: prescription vs. Over-the-Counter toothpaste
Knowledge-focused CompletedThis study looked at how much fluoride remains in saliva after using different toothpastes and mouthrinses. Twenty healthy adults tried four combinations of over-the-counter or prescription toothpaste, with or without a fluoride mouthrinse. The goal was to measure fluoride levels…
Matched conditions: DENTAL CARIES
Phase: EARLY_PHASE1 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated May 17, 2026 05:42 UTC
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Mom or dad, stay or go? study tests best way to calm kids at the dentist
Knowledge-focused CompletedThis study looked at whether a parent's presence during a child's dental treatment affects the child's anxiety and behavior. 72 healthy children aged 4-7 with no prior dental experience were randomly placed into three groups: parent absent, parent behind a barrier, or parent pres…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Ankara Yildirim Beyazıt University • Aim: Knowledge-focused
Last updated May 17, 2026 05:36 UTC
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New study maps hidden factors behind Kids' cavities
Knowledge-focused CompletedThis study looked at 298 children under 6 with early tooth decay in the Hauts-de-France region. Researchers collected data through dental exams and parent questionnaires to understand what factors—like family background, dental habits, and stress—are linked to more severe cavitie…
Matched conditions: DENTAL CARIES
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 17, 2026 05:36 UTC
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Kids' cavities linked to sleep and saliva chemistry, new study finds
Knowledge-focused CompletedThis study looked at 73 children ages 6-12 to see if sleep problems and certain chemicals in saliva are related to cavities and gum health. Researchers measured things like saliva flow, pH, and stress hormones, and compared them to how severe the children's tooth decay was. The g…
Matched conditions: DENTAL CARIES
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated May 17, 2026 05:36 UTC
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Could your Child's cavities be written in their genes?
Knowledge-focused CompletedThis study examined whether certain gene changes make young people more likely to develop severe cavities. Researchers compared children and teens with at least three active cavities to cavity-free young adults. They looked for mutations in genes that affect tooth enamel, which c…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Chewing gum reveals kids' dental treatment success
Knowledge-focused CompletedThis study looked at 100 children aged 6 to 9 with cavities to see if dental treatment improves their chewing. Kids chewed a special two-colored gum before and three months after treatment, and a computer measured how well they mixed the colors. The goal was to understand how fix…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: TC Erciyes University • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Bad teeth, shy speech: study links Kids' oral health to communication confidence
Knowledge-focused CompletedThis study looked at 184 children aged 7-12 to see if dental issues like cavities or missing teeth affect how confident they feel when speaking. Researchers checked their teeth and asked them about their speaking attitudes. The goal was to understand if oral health problems can i…
Matched conditions: DENTAL CARIES
Sponsor: Ezgi Turkyilmaz • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC
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Kids and parents speak out on tooth fillings – study reveals surprising preferences!
Knowledge-focused CompletedThis study looked at what parents and children prefer when it comes to dental fillings for baby molars. Researchers asked 140 parents and kids about their worries and choices to help dentists provide better care. The goal was to make dental visits more comfortable and improve com…
Matched conditions: DENTAL CARIES
Sponsor: Universiti Teknologi Mara • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Saliva secrets: could natural proteins predict cavities in kids?
Knowledge-focused CompletedThis study examined whether certain natural proteins in saliva are linked to severe tooth decay in young children. Researchers compared saliva samples from 50 Turkish children aged 3-6—some with severe cavities and some without. The goal was to better understand why some children…
Matched conditions: DENTAL CARIES
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC
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Can plant extracts beat cavities? new study puts rinses to the test
Knowledge-focused CompletedThis study looked at whether mouth rinses made with plant extracts and fluoride can help protect teeth from cavities and erosion. Twelve healthy adults used different rinses, including a plain water rinse for comparison. Researchers measured mineral loss in tooth samples to see w…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: University of Bern • Aim: Knowledge-focused
Last updated May 13, 2026 16:00 UTC
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Which Kids' dental crown works best? new study has answers
Knowledge-focused CompletedThis study looked at two different brands of stainless steel crowns used to fix cavities in children's baby teeth. The children, aged 2 to 8, had the crowns placed while under general anesthesia. Researchers checked how well the crowns stayed in place and kept the gums healthy, a…
Matched conditions: DENTAL CARIES
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC
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Laser vs. drill: which kills more cavity bacteria?
Knowledge-focused CompletedThis study tested two ways to remove cavities in children: a laser and a traditional drill. Researchers measured how much cavity-causing bacteria (Streptococcus mutans and Lactobacillus) were left in the tooth after each method. 32 children took part, and the goal was to see whic…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Medical University of Sofia • Aim: Knowledge-focused
Last updated May 12, 2026 13:40 UTC
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IBD patients report worse oral health, study finds
Knowledge-focused CompletedThis study looked at how inflammatory bowel disease (IBD) affects oral health and daily life. Researchers compared 138 adults with IBD to people without IBD, using a questionnaire to measure oral health-related quality of life. The goal was to understand which factors, like medic…
Matched conditions: DENTAL CARIES
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 11, 2026 20:52 UTC
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Water wars: school pilot aims to quench student thirst
Knowledge-focused CompletedThis study tested a new program in one school to help students drink more water and avoid sugary drinks. Over 500 students and staff took part to see if the program was easy to use and liked by everyone. The goal was to improve hydration and reduce health issues like cavities and…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Knowledge-focused
Last updated May 11, 2026 20:51 UTC
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Pucker up! kissing may fight cavities, study suggests
Knowledge-focused CompletedThis study looked at whether kissing on the mouth can help neutralize acid in the mouth after drinking sugary or fermented drinks like soda or beer. Acid can weaken tooth enamel and lead to cavities. Researchers gave 33 healthy adults these drinks, then measured their saliva pH e…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Universidad Catolica Santiago de Guayaquil • Aim: Knowledge-focused
Last updated May 06, 2026 16:03 UTC