DENTAL CARIES
Clinical trials for DENTAL CARIES explained in plain language.
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Three ways to stop Kids' tooth decay before it gets worse
Disease control CompletedThis study tested three different treatments to stop early tooth decay in children's baby molars. Researchers compared fluoride varnish, a resin treatment that seals the tooth, and a combination of both. They followed 26 children aged 4-9 for one year to see which approach best p…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Sacide Duman • Aim: Disease control
Last updated Apr 02, 2026 02:11 UTC
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Simple paint stops Kids' cavities without drilling
Disease control CompletedThis study tested two simple, painless treatments to stop cavities in young children who have difficulty sitting through standard dental procedures. Researchers compared applying a silver fluoride liquid to cavities every six months versus combining that with a protective fluorid…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Beaty Dent • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Mouth appliance test reveals which toothpaste fights cavities best
Disease control CompletedThis study tested how well three different toothpastes could repair early-stage tooth decay (cavities). Thirty-one healthy adults wore a removable mouth appliance containing small, pre-weakened tooth samples for several days at a time. Researchers measured how much the toothpaste…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Church & Dwight Company, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New Kids' dental crowns put to the test
Disease control CompletedThis study tested how well BioFlx crowns work for treating cavities in children's baby molars over two years. It involved 28 healthy, cooperative children aged 6 to 9. Researchers checked the crowns' durability and asked both the kids and their parents how happy they were with ho…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: King Abdulaziz University • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Chewing gum test shows if fixing Kids' cavities helps them eat better
Disease control CompletedThis study looked at whether dental treatment for cavities improves how well children can chew their food. Researchers tested 100 children aged 6 to 9 using a special two-colored chewing gum to measure chewing ability before and three months after their dental work. The goal was …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: TC Erciyes University • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Shining a light on cavity care: can blue light boost tooth treatment?
Disease control CompletedThis study looked at whether adding a blue light to a common cavity treatment makes it work better for children. Researchers treated cavities in baby molars with a silver fluoride solution, and for some kids, they also shined a blue light on the tooth. They then measured if the l…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Çanakkale Onsekiz Mart University • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Metal-Free crowns challenge gold standard for Kids' teeth
Disease control CompletedThis study compared two types of crowns for treating large cavities in children's baby molars. Researchers tested whether new metal-free Bioflx crowns work as well as traditional stainless steel crowns over one year. The trial involved 36 children aged 6-8 years, with each child …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: satish vishwanathaiah • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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Better back teeth fillings? study tests Lab-Made vs. chairside options
Disease control CompletedThis study compared two methods for placing tooth-colored fillings in back teeth with cavities. Researchers followed 90 adults for a year to see if fillings made in a dental lab (indirect) performed better than those placed directly in the mouth. They checked how well the filling…
Matched conditions: DENTAL CARIES
Sponsor: Recep Tayyip Erdogan University • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Dental study tests best way to stop clear aligner white spots
Disease control CompletedThis study compared three different remineralizing treatments to see which works best at preventing white spot lesions (early tooth decay) around the attachments used with clear aligners. Forty patients undergoing clear aligner treatment were assigned to use either a special dail…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Bezmialem Vakif University • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Ancient chewing stick takes on modern toothbrush in Kids' dental health trial
Disease control CompletedThis study tested whether a traditional 45°-cut miswak stick works as well as a manual toothbrush for removing plaque from children's teeth. In a 'split-mouth' trial, 82 children aged 6-14 used the miswak on one side of their mouth and a toothbrush on the other to see which clean…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: King Abdulaziz University • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New dental cement tested to save Kids' painful cavities
Disease control CompletedThis study compared two dental procedures for treating deep cavities in children's baby molars. Researchers tested a newer material called Biodentine against a standard treatment to see which better preserved the tooth and reduced pain. The trial involved 28 children aged 4-9 wit…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Mohamed Ahmed Hamdi Abo El Yamin • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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Better fillings for deep cavities? study tests bioactive materials
Disease control CompletedThis study compared two types of dental filling materials for treating deep cavities in back teeth. Researchers tested whether newer 'bioactive' fillings, which interact with the tooth, perform better than traditional fillings over 18 months. They measured how well the fillings h…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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New toothpaste aims to reverse early cavities
Disease control CompletedThis study tested if an experimental fluoride toothpaste could help repair early-stage tooth decay. 47 healthy adults wore a modified partial denture holding small pieces of weakened tooth enamel for two weeks while using the toothpaste. Researchers measured how well the toothpas…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: HALEON • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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Gentle vs. drill: which cavity fix works best for kids?
Disease control CompletedThis study compared three methods for treating cavities in children's baby molars over 18 months. It involved 60 healthy children, each receiving three different treatments on separate teeth: a gentle Hall crown, a silver fluoride paint, and a traditional drill-and-fill. Research…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: TC Erciyes University • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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Which Kids' dental crown holds up best? study compares options
Disease control CompletedThis study compared two brands of stainless steel crowns used to fix cavities in young children's teeth during procedures under general anesthesia. Researchers followed 54 children aged 2-8 for at least six months to see which crown stayed on better and caused fewer problems. The…
Matched conditions: DENTAL CARIES
Sponsor: Bezmialem Vakif University • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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Mouth appliance test reveals best toothpaste for fighting cavities
Disease control CompletedThis study tested three different toothpastes to see which one was best at repairing early-stage tooth decay (cavities). Thirty healthy adults wore a special removable mouthpiece containing small pieces of weakened tooth enamel for several weeks. Researchers measured how well eac…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Church & Dwight Company, Inc. • Aim: Disease control
Last updated Mar 09, 2026 14:24 UTC
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Counseling program aims to stop Kids' cavities from coming back
Disease control CompletedThis study tested whether counseling from a pediatrician and social worker could help families keep follow-up dental appointments after their young children had cavities treated under general anesthesia. Researchers worked with 89 families in Finland to see if this support would …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Helsinki University Central Hospital • Aim: Disease control
Last updated Mar 06, 2026 15:38 UTC
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Can more water at school fight cavities and obesity in kids?
Prevention CompletedThis study tested a school-based program designed to get children to drink more water. Researchers worked with students, teachers, and staff to see if making water more accessible and encouraging its use was practical and could lead to positive changes. They measured if kids used…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Virginia Commonwealth University • Aim: Prevention
Last updated Mar 31, 2026 12:11 UTC
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Could herbal mouthwash be your next cavity fighter?
Prevention CompletedThis small study tested whether mouth rinses containing plant extracts could help prevent tooth decay and erosion. Twelve healthy adults tried different rinses, including a placebo, while wearing special oral appliances with test tooth samples. Researchers measured how well the r…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: University of Bern • Aim: Prevention
Last updated Mar 30, 2026 14:33 UTC
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Cash for cavity prevention: study pays parents to brush Kids' teeth
Prevention CompletedThis study tested whether offering small financial rewards to parents would encourage them to brush their young children's teeth more consistently. Researchers worked with 244 mostly Latino families in early childhood programs, using a smartphone-connected toothbrush to track bru…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: University of California, San Francisco • Aim: Prevention
Last updated Mar 30, 2026 14:32 UTC
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New dental sealant technique aims to lock out cavities
Prevention CompletedThis study tested a new method for applying a protective dental sealant to prevent cavities in young adults. Researchers compared a standard sealant application against a method that first cleans the tooth with a special bioactive glass powder. The goal was to see if the new clea…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Cairo University • Aim: Prevention
Last updated Mar 23, 2026 15:18 UTC
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Simple fluoride gel could shield cancer Patients' teeth from radiation damage
Prevention CompletedThis study tested whether a simple, professionally applied fluoride gel could prevent severe tooth decay in head and neck cancer patients undergoing radiation therapy. About 60 patients were enrolled to see if applying the gel before and after radiation could protect their teeth.…
Matched conditions: DENTAL CARIES
Phase: EARLY_PHASE1 • Sponsor: Texas A & M University Baylor College Of Dentistry • Aim: Prevention
Last updated Mar 02, 2026 15:27 UTC
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New dental filling cures in just 3 seconds
Symptom relief CompletedThis study tested a new type of dental filling material designed to harden in just 3 seconds using a special light. It involved 39 adults who needed fillings in their back teeth. The main goal was to see if these fast-cured fillings caused less pain and sensitivity and lasted wel…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Ivoclar Vivadent AG • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Do bad teeth make kids shy? study links cavities to speaking confidence
Knowledge-focused CompletedThis study looked at whether common dental problems in children, like cavities and crooked teeth, affect how confident they feel about speaking. Researchers examined 184 children aged 7-12 and asked them questions about their speaking attitudes. The goal was to understand if oral…
Matched conditions: DENTAL CARIES
Sponsor: Ezgi Turkyilmaz • Aim: Knowledge-focused
Last updated Apr 02, 2026 02:11 UTC
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Scientists test how much fluoride stays in your mouth
Knowledge-focused CompletedThis study aimed to understand how much fluoride stays in saliva after brushing with regular or prescription toothpaste, and whether adding a fluoride mouthwash makes a difference. Twenty healthy adults from Michigan tried four different combinations of toothpaste and mouthwash. …
Matched conditions: DENTAL CARIES
Phase: EARLY_PHASE1 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Scientists search for clues in Kids' spit to fight severe tooth decay
Knowledge-focused CompletedThis completed study aimed to understand if natural protective substances in saliva are linked to severe cavities in young children. Researchers compared saliva samples from 50 Turkish children aged 3-6, some with severe cavities and some with no cavities. The goal was to gather …
Matched conditions: DENTAL CARIES
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:10 UTC
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A kiss to neutralize? study tests if kissing fights acidic drinks
Knowledge-focused CompletedThis study aimed to see if kissing can help protect teeth from cavities. Researchers gave 45 healthy adults sugary or fermented drinks to make their mouths more acidic, which can weaken tooth enamel. They then tested if kissing a partner could make the mouth less acidic again fas…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Universidad Catolica Santiago de Guayaquil • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Toothpaste put to the test: does it really strengthen your teeth?
Knowledge-focused CompletedThis study tested how well a TheraBreath toothpaste delivers fluoride to teeth and helps rebuild weakened enamel, which can prevent cavities. Thirty-one healthy adults wore a special dental appliance to measure the effects. The goal was to gather scientific data on the toothpaste…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Church & Dwight Company, Inc. • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Researchers ask: how do mouth problems affect daily life for IBD patients?
Knowledge-focused CompletedThis study aimed to understand how oral health issues like gum disease, cavities, and tooth loss affect the daily life and well-being of people with Crohn's disease or ulcerative colitis. Researchers compared survey responses from 138 adults with IBD to people without IBD. The go…
Matched conditions: DENTAL CARIES
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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What do families really want for their Kids' cavities?
Knowledge-focused CompletedThis study asked parents and their children (aged 5-12) about their preferences for different types of fillings in baby molars. Researchers used a questionnaire to understand what influences families' choices, like the look or material of the filling. The goal is to help dentists…
Matched conditions: DENTAL CARIES
Sponsor: Universiti Teknologi Mara • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Scientists hunt for the 'Cavity Gene' in kids
Knowledge-focused CompletedThis study aimed to understand why some children get many cavities while others get none, by looking for possible genetic causes. Researchers compared saliva samples from 250 children with severe cavities to 160 young adults with no cavities. The goal was to find specific gene ch…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Researchers probe why some kids get worse cavities
Knowledge-focused CompletedThis study aimed to understand why some young children develop more severe cavities than others. Researchers examined 298 children under age 6 with early tooth decay and surveyed their parents about family habits, knowledge, and background. The goal was to identify different prof…
Matched conditions: DENTAL CARIES
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC
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Should parents stay or go? dentists test what calms kids most
Knowledge-focused CompletedThis study aimed to find out if having a parent in the room helps or hurts a child's comfort during a dental procedure. Researchers observed 72 children, aged 4-7, getting a cavity filled. The kids were randomly assigned to have their parent present, absent, or sitting behind a b…
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Ankara Yildirim Beyazıt University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:17 UTC
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Video vs. In-Person: which trains dentists better to stop cavities?
Knowledge-focused CompletedThis study tested whether dental students could learn to apply protective tooth sealants just as well by watching a training video as they could from in-person instruction. Researchers followed 50 children for three months to see how well the sealants stayed on their back teeth. …
Matched conditions: DENTAL CARIES
Phase: NA • Sponsor: Mansoura University • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:47 UTC
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Could your Child's sleep be causing cavities?
Knowledge-focused CompletedThis study aimed to understand if sleep problems and the chemical makeup of saliva are connected to tooth decay and gum health in children. Researchers examined 73 healthy children aged 6-12, comparing those with many cavities to those with few or none. They collected saliva samp…
Matched conditions: DENTAL CARIES
Sponsor: Bezmialem Vakif University • Aim: Knowledge-focused
Last updated Mar 09, 2026 14:25 UTC