Can special toothpaste stop kids' cavities? new study tests fluoride vs. probiotics
NCT ID NCT07579403
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested whether fluoride or probiotic toothpaste can prevent cavities in 508 children aged 4-5. Kids brushed twice daily for 12 months with either fluoride, probiotic, or plain toothpaste. Researchers also surveyed eating and brushing habits to find risk factors for cavities.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fluoride toothpaste and probiotic toothpaste
What this could lead to
If successful, this could point toward better toothpaste options for preventing cavities in young children.
What could go wrong
This is a completed Phase 4 study in one city, so results may not apply to all children. Toothpastes only reduce risk, not eliminate cavities entirely.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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The Affiliated Hospital of Qingdao University
Qingdao, Shandong, 266003, China